Early aggressive fluid resuscitation shows no difference in respiratory failure days in severe acute pancreatitis
Early heavy fluids did not help breathing days in severe pancreatitis patients
This secondary analysis of a multicenter randomized controlled trial in 259 patients with predicted severe acute pancreatitis found no signi…
A study of 259 patients found that using large amounts of fluid early on did not improve breathing compared to moderate fluid use. In fact, …
Case report and review highlights ultrasound-guided microwave ablation for metastatic breast cancer in a single patient
Microwave Ablation Controls Breast Metastasis for Three Years
This case report and review of the literature describes ultrasound-guided microwave ablation in a 59-year-old female with metastatic breast …
A single session of microwave ablation kept a breast cancer metastasis under control for three years with no major side effects.
Sepsis survivors face high readmission, mortality, and long-term impairments
Sepsis survivors face high readmission and death rates
A meta-analysis of 76 studies found that sepsis survivors have a 44% readmission rate at 1 year and rising mortality, with persistent cognit…
One year after sepsis, 44% of survivors are readmitted and 15% die within a month.
Meta-analysis shows association between exclusive human milk and reduced mortality in gastroschisis
Exclusive Breast Milk May Lower Death Risk For Gastroschisis Babies
This meta-analysis of 3661 infants with gastroschisis evaluates the impact of exclusive human milk versus formula. The findings suggest an a…
Exclusive breast milk may lower death risk for babies with gastroschisis compared to formula feeds.
Selective decontamination of the digestive tract reduces hospital mortality in mechanically ventilated ICU adults
Selective decontamination lowers death risk for ICU patients on ventilators
This systematic review and meta-analysis evaluated selective decontamination of the digestive tract (SDD) versus standard care or placebo in…
A massive analysis of 32 studies shows selective decontamination of the digestive tract lowers hospital death rates for adults on ventilator…
Continuous glucose monitoring may reduce mortality and hypoglycemia in ICU patients compared to point of care testing
Meta-analysis links continuous glucose monitoring to lower mortality risk in ICU patients
This meta-analysis evaluated continuous glucose monitoring versus point of care blood glucose measurements in ICU patients.
A new analysis suggests continuous glucose monitoring may lower mortality and hypoglycemia in ICU patients, though evidence remains very unc…
Higher Intraoperative Mechanical Power Linked to Impaired Oxygenation and Pulmonary Complications After Orthopedic Surgery
Higher surgical machine power linked to worse lung oxygen levels after orthopedic surgery
This post hoc analysis of a cluster factorial randomized trial included 2,582 patients undergoing orthopedic surgery.
Using more power during orthopedic surgery was linked to lower oxygen levels and more lung complications in patients recovering from these o…
ICU CogHab cognitive rehabilitation feasibility study in ICU survivors with cognitive impairment
Feasibility study tests cognitive rehab for ICU survivors with cognitive impairment
This randomised controlled feasibility study evaluated a cognitive rehabilitation intervention in 83 ICU survivors with cognitive impairment…
A feasibility study found that cognitive rehabilitation can be introduced to ICU survivors, though recruitment and retention remain challeng…
Hypophosphatemia during KRT linked to fewer ventilator-free days in critically ill patients
Low phosphate during dialysis linked to fewer ventilator-free days
This post hoc analysis of the STARRT-AKI trial found that hypophosphatemia during kidney replacement therapy was associated with fewer venti…
A new analysis finds that critically ill patients who develop low phosphate during kidney therapy spend fewer days off ventilators.
Systematic review and meta-analysis of procalcitonin diagnostic accuracy in community-acquired bacteraemia
A low procalcitonin test helps rule out dangerous blood infections in adults
This systematic review and meta-analysis evaluated procalcitonin levels against blood culture results in 192 529 adults with community-acqui…
A low procalcitonin test can help doctors rule out serious blood infections in adults, but results vary and clinical judgment is still neede…
Meta-analysis finds dietary fibre reduces metabolic endotoxemia and inflammatory cytokines
Adding dietary fibre may lower inflammation markers in people with metabolic endotoxemia
This systematic review and meta-analysis of 773 participants found that dietary fibre supplementation significantly decreased serum lipopoly…
A review of 773 people found that adding dietary fibre significantly lowered inflammation markers linked to chronic disease risk.
Non-routine GRV monitoring does not increase feeding intolerance in ventilated adults
Nurses Can Cut Daily Checks Without Hurting Feeding Plans
This randomized non-inferiority trial compared non-routine (once daily) versus routine 4-hourly gastric residual volume (GRV) monitoring in …
Cutting daily stomach checks saves nursing time without causing more vomiting or feeding problems for ICU patients.