Network meta-analysis finds PMX and HA 330 blood purification may reduce mortality in severe septic shock
Two blood purification devices linked to lower death rates in severe septic shock
A Bayesian network meta-analysis of 31 RCTs involving 2678 patients with severe septic shock found that the TORAYMYXIN™ filter (PMX) and HA …
Two specific blood purification devices are linked to lower death rates for patients with severe septic shock compared to standard treatment…
Testosterone gel fails to normalize serum levels in critically ill ICU patients in pilot RCT
Can testosterone gel help critically ill men? A small study finds no clear benefit
A pilot RCT of 30 critically ill ICU patients on vasopressors and mechanical ventilation found 14-day testosterone gel administration did no…
Testosterone gel did not improve hormone levels or safety in critically ill men needing breathing machines and blood pressure support.
Balanced salt solution in pediatric septic shock linked to lower AKI and RRT rates versus normal saline
Balanced fluids may reduce kidney injury in children with septic shock, study finds
A meta-analysis of 5 RCTs involving 992 children with septic shock found balanced salt solution (BSS) was not associated with reduced mortal…
Using balanced salt solutions instead of normal saline helps children with septic shock avoid kidney injury and dialysis, a new analysis of …
Remimazolam infusion associated with easier mask ventilation than propofol during anaesthesia induction
Small study finds remimazolam may ease mask ventilation during anesthesia induction
In a randomised trial of 76 adults undergoing elective surgery, continuous remimazolam infusion was associated with less mask ventilation di…
Patients given remimazolam had easier breathing through a mask and more stable blood pressure during surgery induction compared to propofol.
VR and in-person sepsis simulation show similar skill outcomes in medical student pilot study
Can virtual reality teach doctors to spot sepsis as well as real training?
A randomized comparative pilot study of 32 final-year medical students found no statistically significant differences in mQSAT scores or sep…
Virtual reality training helped medical students spot when patients needed intensive care better than traditional practice methods in a new …
Serum procalcitonin shows moderate accuracy for sepsis diagnosis in critically ill ICU patients
Blood test for sepsis shows moderate accuracy in critically ill ICU patients
A systematic review and meta-analysis of 1,098 critically ill adult ICU patients with suspected infection found serum procalcitonin had pool…
A blood test for sepsis correctly identifies patients with the condition about 72% of the time, but its accuracy is moderate and evidence is…
Inspiratory muscle training shows no clear effect on physical function in critically ill adults on mechanical ventilation
Breathing muscle training shows uncertain effect on physical function in ICU patients
A systematic review and meta-analysis of 18 studies in adults requiring invasive mechanical ventilation for ≥24 hours found inspiratory musc…
Breathing muscle training for ICU patients on ventilators may not improve their ability to move and perform daily activities, with effects r…
NIRS-measured cerebral oxygen saturation predicts ROSC and neurological outcomes in adult cardiac arrest
Brain oxygen monitoring during CPR may help predict recovery chances after cardiac arrest
A meta-analysis of 3880 nontraumatic adult cardiac arrest patients found that higher delta regional cerebral oxygen saturation (rSO) values …
Measuring brain oxygen during CPR helps predict if a heart restarts and if patients will recover brain function after cardiac arrest.