Dynamic ctDNA monitoring during neoadjuvant chemotherapy identifies high-risk rectal cancer patients
Blood test during chemo may help predict rectal cancer treatment response
A biomarker substudy of a multicenter RCT in 153 patients with low-/intermediate-risk locally advanced rectal cancer found that dynamic ctDN…
A blood test tracking tumor DNA during chemo can predict which rectal cancer patients won't respond well to treatment before surgery.
Oral nutritional interventions associated with reduced clinical events in adults with cirrhosis
Can better nutrition help people with advanced liver disease?
A systematic review and meta-analysis of 3,128 adults with cirrhosis found oral nutritional interventions were associated with reduced risks…
Better nutrition linked to fewer hospital visits and lower risk of serious problems for adults with advanced liver disease.
Meta-analysis links higher BMI to increased early-onset colorectal cancer risk
Does weight affect colon cancer risk in younger adults? A new analysis finds a link
A systematic review and meta-analysis of 11 cohort studies found that overweight/obesity (BMI ≥25 kg/m²) was associated with higher early-on…
Being overweight or obese is linked to a 59% higher risk of colon cancer before age 50, with men and those with obesity facing the greatest …
Regular antithrombotic use associated with increased nonbiliary pancreatitis risk in UK Biobank cohort
Large UK study finds link between blood-thinning drugs and pancreatitis risk
A prospective cohort study of 431,754 UK Biobank participants found regular antithrombotic drug use was associated with a 31% increased risk…
Regular blood-thinning drug use is linked to a 31% higher risk of a specific pancreatitis type, with clopidogrel showing the strongest conne…
Web portal developed for personalized colorectal cancer risk prediction using genetic and lifestyle factors
Can a new web tool better predict your colon cancer risk?
A web-based portal called MyGeneRisk Colon was developed to predict colorectal cancer risk by incorporating genetic, demographic, family his…
A new web tool combines your genetic data, family history, and lifestyle factors to give a clearer picture of your colon cancer risk.
Corticosteroids in cirrhotic shock show no mortality benefit but increase bleeding and organ failure risk
Corticosteroids help resolve shock in cirrhosis patients but don't improve survival
A meta-analysis of 514 cirrhotic patients with septic or distributive shock found low-dose corticosteroids did not reduce in-hospital mortal…
Low-dose corticosteroids help resolve shock in cirrhosis patients but do not improve overall survival and increase bleeding risks.
In Silico Modeling Predicts Fezolinetant Hepatotoxicity Risk in MAFLD Population
Could a menopause drug harm the liver? A computer model offers clues
Quantitative systems toxicology modeling simulated fezolinetant hepatotoxicity in virtual populations.
A computer model predicts a menopause drug might cause rare liver injury in people with fatty liver disease, but higher doses could be safer…
Prehabilitation improves functional capacity and reduces severe complications in elective colorectal cancer surgery
Can a few weeks of exercise before colon cancer surgery help you recover better?
A meta-analysis of 976 patients undergoing elective colorectal cancer resection found preoperative prehabilitation significantly improved po…
Pre-surgery exercise before colon cancer operations helps patients walk farther and lowers their risk of severe complications after the proc…
New-onset diabetes in adults over 50 associated with higher pancreatic cancer risk within 3 years
Could new diabetes after age 50 signal hidden pancreatic cancer?
A systematic review found individuals around 50 years and over with new-onset diabetes have a higher risk for pancreatic ductal adenocarcino…
New diabetes after age 50 might signal hidden pancreatic cancer, as patients face a higher risk of diagnosis within three years compared to …
Meta-analysis finds 3.2% prevalence of germline MMR mutations in patients with upper tract urothelial carcinoma
Study finds 3.2% of upper tract urothelial cancer patients have inherited DNA repair mutations
A systematic review and meta-analysis of 14 studies including 2378 patients with upper tract urothelial carcinoma (UTUC) found a pooled prev…
About 3% of upper tract urothelial cancer patients carry inherited DNA repair mutations that link their cancer to Lynch syndrome and affect …
Pilot trial finds no between-group muscle mass benefit from HMB supplement in cirrhosis sarcopenia
Small pilot study tests nutritional supplement for muscle loss in liver cirrhosis
A pilot randomized controlled trial of 21 patients with stable decompensated cirrhosis and sarcopenia found no significant between-group dif…
A nutritional supplement with HMB improved leg strength and body composition in cirrhosis patients, though it did not increase overall muscl…
Nurse-led music intervention shows preliminary benefit for cognitive impairment in colorectal cancer patients
Can listening to your favorite music help clear cancer treatment brain fog?
A pilot RCT of 70 colorectal cancer patients with cognitive impairment found a 9-week nurse-led individualized music-listening intervention …
Listening to favorite music helped colorectal cancer patients feel less brain fog, depression, and fatigue while sleeping better during trea…