Meta-analysis finds 15.4% pooled TTI prevalence in Cameroonian blood donors, higher risk in family donors
How many blood donations in Cameroon carry dangerous infections?
A systematic review and meta-analysis of 36 studies involving approximately 105,000 blood donations in Cameroon found a pooled transfusion-t…
A new analysis of over 100,000 blood donations in Cameroon found that 15.4% carry dangerous infections like HIV, hepatitis, or syphilis, wit…
HBV RNA positivity at nucleoside analogue discontinuation linked to higher relapse risk in chronic hepatitis B
What happens when hepatitis B patients stop their medication? A key marker may predict relapse
A meta-analysis of 21 cohort studies including 2,043 chronic hepatitis B patients found HBV RNA-positive individuals had 1.9-fold higher vir…
Stopping hepatitis B medication carries higher relapse risk if a specific viral marker called HBV RNA is still detectable in the blood.
Review describes Borrelia burgdorferi immune evasion strategies that enable persistent infection across vertebrate hosts
Review explains how Lyme disease bacteria persist by altering host immune responses
A systematic review synthesizes evidence on Borrelia burgdorferi immunobiology in vertebrate hosts, including humans.
Lyme disease bacteria survive by redirecting the immune system to avoid full elimination, allowing the infection to persist across different…
HCV treatment with direct-acting antivirals linked to reduced alcohol use in people who inject drugs
HCV treatment linked to reduced alcohol use in people who inject drugs
A secondary analysis of a pragmatic RCT in 755 people who inject drugs (PWID) found that achieving sustained virological response (SVR) was …
People who inject drugs and cured of hepatitis C showed lower alcohol use scores at every follow-up visit compared to their baseline.
Review finds probiotic-mast cell interplay in gut inflammation remains poorly defined
Review finds limited understanding of how probiotics interact with gut cells in inflammation
A systematic mini-review synthesizing existing evidence found the functional interplay between probiotics and mast cells in gut health and d…
Probiotics and gut immune cells called mast cells might interact to influence inflammation in conditions like food allergies, but scientists…
Adjuvant NSAIDs associated with improved DFS in resected PIK3CA-mutated colorectal cancer
NSAID therapy after surgery may help prevent colorectal cancer recurrence in some patients
A meta-analysis of 789 patients with resected PIK3CA-mutated colorectal cancer found adjuvant NSAID therapy (aspirin or COX-2 inhibitors) wa…
Taking anti-inflammatory drugs like aspirin after colorectal cancer surgery may lower the risk of the cancer returning in patients with a sp…
TCM formulas and acupuncture show potential for radiation enteropathy in limited evidence
Can Traditional Chinese Medicine help with radiation damage to the gut?
A systematic review found Traditional Chinese Medicine botanical formulas and acupuncture may improve symptoms and reduce inflammatory marke…
Traditional Chinese Medicine formulas and acupuncture may ease gut damage from radiation therapy, with studies showing symptom relief and re…
Review explores chronic enterocolitis in rhesus macaques as potential model for post-infectious IBS
Review explores monkey intestinal disease as possible model for human IBS
A systematic review examined chronic enterocolitis (CE) in colony-housed rhesus macaques, which leads to chronic diarrhea and severe weight …
A scientific review examined a chronic intestinal disease in rhesus macaques that causes severe diarrhea and weight loss.
Anti-EGFR rechallenge improves response and PFS but not OS in ctDNA wild-type chemorefractory mCRC
Anti-EGFR rechallenge shows benefit for some advanced colorectal cancer patients
A meta-analysis of three phase II randomized trials (n=320) in pretreated ctDNA RAS/BRAF wild-type mCRC found anti-EGFR rechallenge signific…
Giving anti-EGFR drugs again helps some advanced colorectal cancer patients shrink tumors and delay growth, though it does not extend overal…
Post hoc analysis links TMB ≥9 or BRAF-V600E to longer PFS with chemo-nivolumab in MSS/pMMR mCRC
Could two simple blood tests help predict which colon cancer patients benefit from immunotherapy?
A post hoc analysis of the METIMMOX RCT in patients with metastatic MSS/pMMR colorectal cancer found that in the experimental arm (alternati…
Two simple blood tests and tumor markers can predict which colon cancer patients live longer on immunotherapy combined with chemotherapy.
Meta-analysis links ultra-processed food consumption to increased MASLD risk in 1.2 million participants
Do ultra-processed foods raise your risk of fatty liver disease?
A meta-analysis of 7 prospective cohort studies with 1,272,317 participants found higher ultra-processed food consumption was associated wit…
Eating more ultra-processed foods like sugary drinks and ready meals raises your long-term risk of developing fatty liver disease, a conditi…
Platinum-based intraperitoneal chemotherapy improves disease-free survival after curative CRC resection
Study reviews chemotherapy method for colorectal cancer after surgery
A meta-analysis of 1,264 adults receiving curative colorectal cancer resection found platinum-based prophylactic intraperitoneal chemotherap…
Giving chemotherapy directly into the abdomen after colorectal cancer surgery helped patients stay cancer-free longer without adding serious…