Cross-sectional study observes differences in cardiovascular regulatory responses in mild cognitive impairment
Researchers find heart rhythm changes linked to mild cognitive impairment
This cross-sectional observational study investigated cardiovascular regulatory responses to acute cognitive stress in community-dwelling ol…
New observations suggest that how the heart responds to mental stress may differ in people with early signs of memory loss.
DISCO metric from proteomics predicts mortality and frailty in older adults
Brain entropy predicts death better than existing aging clocks in older adults
This cohort study in older adults found that a proteomic-based DISCO metric outperforms existing dysregulation measures and matches epigenet…
A new measure of brain entropy predicts death and disease in older adults as well as the best current aging clocks.
Prediabetes Associated With Higher Incidence of Frailty and Functional Deficits in Adults Aged 50 Years or Older
Prediabetes Linked to Higher Frailty Risk in Older Adults
This cohort study analyzed 18,571 adults aged 50 years or older across five longitudinal aging cohorts.
In a large study of over 18,000 older adults, prediabetes was associated with higher rates of frailty and functional decline compared to nor…
Machine learning analysis identifies drivers of medication burden in older Nepalese patients
Older Adults in Nepal Face Hidden Pill Burden
This original article reports an observational study using machine learning to predict medication burden and adherence in older patients fro…
Seniors in Nepal are struggling with too many prescriptions, often needing help just to keep track — and it’s quietly harming their health.
Personalized swallowing rehab improves outcomes after oral cancer surgery
New Swallowing Therapy Helps Oral Cancer Patients Eat and Speak More Easily
This randomized controlled trial in 300 patients with oral squamous cell carcinoma found that a personalized swallowing rehabilitation progr…
Personalized swallowing therapy helps oral cancer patients recover faster, eat more naturally, and avoid dangerous complications like pneumo…
Infection status associated with hypoxemia and death rates varying by virus type in a large US cohort
Triple Virus Infections Rarer Than Feared — Here’s the Real Risk
This cohort study of 835,987 triple-tested patients in the US Veterans Health Administration examined associations between infection status …
It’s winter. Your throat is scratchy. Your chest feels tight.
Narrative review on mpMRI and PSMA PET/CT for radiorecurrent prostate cancer restaging
Two imaging tests together spot prostate cancer return more accurately
This narrative review synthesizes evidence on mpMRI and PSMA-targeted PET/CT for restaging radiorecurrent prostate cancer.
For men with suspected prostate cancer return, combining two scans catches more tumors and avoids unnecessary biopsies.
AI-assisted Bayesian framework identifies Alzheimer's gene pathways in single-cell RNA data
AI finds hidden Alzheimer's genes in brain data
This observational study applied a generative AI-assisted Bayesian-frequentist hybrid framework to single-cell RNA sequencing data from the …
A new AI method uncovered Alzheimer's-related genes that standard analysis missed, pointing to fresh biological pathways.
Mixed-methods review evaluates usability of iSupport-Malaysia for dementia caregivers in Malaysia
New Dementia Tool Speaks Your Language
This mixed-methods review assesses the iSupport-Malaysia platform, a culturally adapted multimedia web-based psychoeducational intervention …
This new tool could finally bridge the gap between global dementia research and the real-world needs of Malaysian families.
Nocturnal sensor signals may predict next-day agitation in dementia cohorts
Sleep Sensors May Predict Dementia Agitation Before It Starts
This cohort study used under-mattress sensors in long-term care and home cohorts (N=55 and N=18) to assess nocturnal signals for predicting …
New sleep sensors can spot signs of dementia agitation before it starts, helping caregivers prepare for difficult days.
Genome-wide association study identifies inverse association between HSV-1 DNA and Alzheimer's disease risk
Alzheimer’s Brains Have Less Herpes Virus DNA Than Expected
This observational genome-wide association study examined HSV-1 DNA presence in persons with Alzheimer's disease and controls.
A new look at brain data suggests the herpes virus might not be the cause of Alzheimer’s after all.
Chinese BERNCA-NH shows acceptable preliminary psychometrics in 251 nursing assistants
Researchers adapted a nursing care survey for use in Chinese long-term care homes
A cross-sectional survey of 251 nursing assistants in Chinese long-term care homes examined the translated Basel Extent of Rationing of Nurs…
A new Chinese survey tool helps nursing assistants measure unfinished care in long-term homes, offering a practical way to track quality gap…