Discordant multimorbidity linked to poorer health status and higher healthcare use in Chinese adults
Study in China finds certain disease patterns linked to poorer health in older adults
An observational study of 8,974 Chinese adults aged >45 years found discordant multimorbidity (conditions from different disease groups) was…
A study of over 8,900 Chinese adults over 45 examined how different combinations of chronic diseases affect health.
Phase 3 trial of TMB-001 topical ointment for congenital ichthyosis reports no efficacy results
Phase 3 trial tests topical ointment TMB-001 for congenital ichthyosis
A phase 3, randomized, double-blind, vehicle-controlled trial in 153 subjects with congenital ichthyosis (RXLI or ARCI subtypes) evaluated T…
A new ointment for congenital ichthyosis is being tested in a rigorous study to see if it can safely improve dry, scaly skin symptoms.
In Silico Platform Shows Promise for Creating Personality-Stable Elderly Digital Twin Agents
Researchers develop a digital twin platform to simulate elderly personality traits
An in silico development study evaluated the ELDER-SIM platform for creating elderly digital twin agents.
A new computer platform creates stable digital twins of elderly people to safely test mental health care strategies before trying them with …
Scoping review identifies 19 factors influencing caregiver support for older adults in rural areas
What makes caregiving in rural areas so hard? A review finds 19 key challenges
A scoping review of 25 studies examined factors influencing caregiver support within integrated care for older adults in rural areas.
Rural caregivers face 19 specific hurdles like isolation, money worries, and poor internet access that make supporting aging parents incredi…
Systematic review finds predictive models for dysphagia risk in older adults show variable performance
Can we predict swallowing trouble in older adults before it happens?
A systematic review and meta-analysis of 17 studies in older adults found predictive models for dysphagia risk had a pooled AUC of 0.82 (95%…
A new analysis shows we might be able to spot swallowing problems in older adults before they become serious.
Exergaming improves strength and balance versus conventional therapy in healthy older adults
Exergaming may improve strength and balance in healthy older adults more than conventional exercise
A systematic review and meta-analysis of 25 RCTs involving 2078 healthy older adults found exergaming significantly improved timed up-and-go…
Playing active video games improved balance and leg strength more than standard exercise for healthy older adults, especially when done at l…
CBD oil shows no surrogate evidence of drug interactions with opioids or benzodiazepines in advanced cancer patients
Study finds CBD oil did not increase side effects when taken with certain cancer medications
A randomized controlled trial in advanced cancer patients found no evidence from surrogate measures that CBD oil increased adverse effects o…
Advanced cancer patients taking CBD oil alongside pain and mental health drugs did not experience increased side effects or drug interaction…
Qualitative study identifies themes influencing adherence to foot strengthening in older adults
What helps older adults stick with foot-strengthening exercises?
A qualitative component of an RCT explored factors influencing adherence to a 12-week supervised foot strengthening program in 12 older adul…
Older adults stick with foot-strengthening exercises best when they get clear trainer instructions, helpful materials, and flexibility in th…
Interprofessional medication review shows non-significant improvement in prescribing appropriateness for older ED patients
Medication review for older emergency patients did not show clear benefit over standard care
A randomized controlled trial of 151 older adults admitted to an emergency department found that a structured, patient-oriented, interprofes…
A structured medication review for older emergency patients did not show clear benefit over standard care in improving prescription safety.
Sarcopenic obesity prevalence is 28% in adults with advanced knee OA and severe obesity
Sarcopenic obesity found in 28% of adults with severe knee osteoarthritis and obesity
A cross-sectional baseline analysis of a pilot RCT (n=50) found sarcopenic obesity prevalence was 28% among adults with advanced knee OA and…
Nearly one-third of adults with severe knee arthritis and obesity have low muscle mass, leading to worse walking distance, function, and qua…