Gene therapy reduces bleeding rates and factor use in adults with severe hemophilia A
Can gene therapy reduce bleeding and treatment burden for adults with severe hemophilia A?
A systematic review and meta-analysis of adults with severe/moderately severe hemophilia A found gene therapy reduced annualized bleeding ra…
For adults with severe hemophilia A, gene therapy may offer a way to bleed less and rely far less on regular infusions.
CellSearch CMMC assay shows analytical sensitivity for non-invasive MRD monitoring in multiple myeloma
Could a simple blood test replace painful bone marrow biopsies for myeloma monitoring?
A study of unspecified design evaluated the analytical performance of the CellSearch CMMC assay for minimal residual disease monitoring in m…
A new blood test can detect single cancer cells left after multiple myeloma treatment, offering a less invasive way to monitor disease level…
Phase 1b trial finds tafasitamab combinations manageable in Japanese B-cell NHL patients
Early study tests tafasitamab alone and in combinations for Japanese lymphoma patients
A phase 1b trial in 24 Japanese patients with relapsed/refractory or untreated B-cell NHL assessed tafasitamab alone or in combination.
Japanese lymphoma patients received new drug tafasitamab alone or with others, showing manageable side effects like low blood counts and nau…
Phase 3 trial of damoctocog alfa pegol in previously treated children with severe haemophilia A
Phase 3 trial studies new treatment for severe haemophilia A in children
A phase 3 clinical trial evaluated damoctocog alfa pegol in previously treated children aged 7 to 12 years with severe haemophilia A.
A new treatment for severe haemophilia A in children aged 7 to 12 is being tested in a Phase 3 trial to check its safety and effectiveness.
Damoctocog alfa pegol shows safety and maintained bleed protection in children with severe haemophilia A
Study finds haemophilia drug safe and effective in children over six months
A phase 3, open-label, single-arm study of 35 previously treated children aged 7 to <12 years with severe haemophilia A found no adverse eve…
A haemophilia drug prevented bleeds in children aged 7 to under 12, with no severe side effects and no one stopping treatment due to bad rea…
Case report describes likely first autochthonous Chagas disease case in Missouri blood donor
Blood donor in Missouri tests positive for Chagas disease, likely first local case
A case report describes a blood donor in Missouri with a positive screening result for Trypanosoma cruzi antibodies.
A Missouri blood donor likely represents the first local case of Chagas disease, a parasite usually found in Latin America.
CDC updates blood lead reference value policy for US population
What does the CDC's new lead level guidance mean for your family?
The CDC has updated its policy on the blood lead reference value.
The CDC lowered the blood lead level that triggers concern, meaning some families may now get different advice on next steps for their child…
Single case report describes durable response to nivolumab in relapsed ALK+ large B-cell lymphoma
Can a common immunotherapy drug help a rare, aggressive lymphoma?
A case report describes one adult patient with stage IV, relapsed/refractory ALK+ large B-cell lymphoma who received off-label nivolumab.
A rare, aggressive lymphoma that failed four treatments responded rapidly to an immunotherapy drug not approved for this cancer, offering ho…
Meta-analysis reports 53% 2-year overall survival after haploidentical HSCT in older adults
Study reviews survival rates for older adults after haploidentical stem cell transplants
A systematic review and meta-analysis of 16 studies including 1,268 adults aged ≥60 years with hematologic malignancies found pooled 2-year …
For older adults with blood cancers, haploidentical stem cell transplants show a two-year survival rate of 53%, though results vary widely b…
R-CVP after radiotherapy improves progression-free survival in early-stage follicular lymphoma
Can adding a drug cocktail to radiation help keep early lymphoma from returning?
In a multicenter RCT with 150 patients with early-stage follicular lymphoma and 11.3-year median follow-up, involved-field radiotherapy plus…
Adding R-CVP drugs to radiation therapy helps early-stage lymphoma patients stay cancer-free longer, with mostly temporary side effects and …
Observational study finds race, ethnicity, and socioeconomic factors affect hemodialysis-associated S. aureus bloodstream infections
Why do race and income affect infection risk for people on dialysis?
An observational study of U.S. hemodialysis patients found that race, ethnicity, and socioeconomic factors were associated with hemodialysis…
A new analysis shows that serious bloodstream infections in dialysis patients are linked to race, ethnicity, and socioeconomic background.
L-arginine shows no significant benefit for pain or hospital outcomes in sickle cell disease meta-analysis
L-arginine shows no clear benefit for sickle cell pain crises in analysis
A systematic review and meta-analysis of 8 RCTs involving 830 patients with sickle cell disease found no statistically significant benefit o…
A new analysis of eight trials found that the supplement L-arginine offers no benefit for pain or hospital stays in sickle cell disease pati…