Meta-analysis finds 47% inconsistent condom use among female sex workers in Africa
Half of African sex workers skip condoms. Here is why.
A systematic review and meta-analysis of 23,496 female sex workers across African countries found a pooled prevalence of inconsistent condom…
Simple changes like better condom supply and mental health support could save lives right now.
Galantamine showed no cognitive benefit in people with HIV-associated neurocognitive disorders.
Why Galantamine Failed to Help
In a double-blind, randomized, placebo-controlled crossover study, people with HIV on antiretroviral therapy received galantamine or placebo…
Galantamine, a drug used for memory loss, did not improve brain fog in people with HIV, even though it increased a key inflammation marker.
Mindfulness-based cognitive therapy improved happiness and mood in women living with HIV compared to control.
Mindfulness Boosts Happiness for Women Living with HIV
This randomized controlled trial enrolled 92 women living with HIV in Ahvaz, Iran. Participants receiving mindfulness-based cognitive therap…
A mental workout called mindfulness therapy significantly lifted happiness and reduced depression for women living with HIV in Iran.
Acute chikungunya infection linked to T cell suppression and elevated pro-inflammatory cytokines
Why Chikungunya Pain Lingers: A Surprising Immune System Misfire
A prospective cohort study of 34 patients with acute chikungunya fever and 20 healthy controls in China found significant suppression of CD3…
Chikungunya fever causes lingering joint pain by suppressing immune cells and spiking inflammation, especially in older adults and men.
mRNA-1273 shows greater COVID-19 protection than NVX-CoV2705 in retrospective US cohort study
New Data Shows One Vaccine Type Works Better
A retrospective matched cohort study of 103,710 US insured adults found mRNA-1273 vaccination was associated with lower rates of medically-a…
In a head-to-head comparison, the mRNA COVID-19 vaccine was more effective at preventing severe outcomes than the protein-based vaccine duri…
ARTIC-based amplicon sequencing assay evaluated for respiratory syncytial virus detection accuracy and lineage identification.
A New Genetic Tool Could Predict the Next RSV Wave Before It Starts
This evaluation of an assay analyzed 214 deidentified remnant clinical specimens from the Georgia Public Health Laboratory. The ARTIC-based …
This new testing method gives health officials a powerful early warning system to track dangerous RSV strains as they evolve.
Cross-sectional study finds high antibiotic use for productive cough in Kenyan clinic patients
Your Cough Could Be Fueling a Global Health Crisis. Here’s How.
A cross-sectional study of 400 adults with productive cough attending chest and tuberculosis clinics in Nairobi found 86.7% used antibiotics…
The way people access common antibiotics for a cough is often informal and risky, creating a direct path for deadly, drug-resistant infectio…
Phase 1 trial shows vaginal L. crispatus biotherapeutics colonize in bacterial vaginosis patients
A Simple Swab Could Stop Bacterial Vaginosis From Coming Back
A phase 1 randomized trial in 71 participants with bacterial vaginosis in the US and South Africa tested vaginally delivered multi-strain La…
For the millions who struggle with BV that keeps returning, this early research points to a promising new strategy: using beneficial bacteri…
Contezolid Shows Lower CSF Concentrations Than Linezolid in Tuberculous Meningitis
New Drug Reaches Brain in Tuberculosis Fight
A small randomized study in 10 tuberculous meningitis patients compared CSF concentrations of contezolid versus linezolid. Linezolid achieve…
A new tuberculosis drug reaches the brain effectively and safely, offering hope for the deadliest form of the infection.
Meta-analysis classifies 345 global tick-borne Alpharhabdovirinae virus strains into 12 phylogenetic clusters.
Hidden Tick Viruses Could Affect Humans
This meta-analysis evaluated the phylogenetic classification of 345 tick-borne Alpharhabdovirinae (TBA) virus sequences from a global settin…
A global study reveals 12 distinct clusters of tick-borne viruses, some with potential to infect humans, as climate change expands tick rang…
Chikungunya seroprevalence was 34.3% overall, significantly higher in urban Colombo communities compared to semi-urban areas.
A Silent Threat Reawakens: Why a Major City Was Primed for an Outbreak
This observational cohort study assessed age-stratified chikungunya-specific IgG seroprevalence among 1,196 residents in Colombo, Sri Lanka,…
After 16 years without cases, Colombo's dense urban neighborhoods left residents defenseless against a chikungunya outbreak that hit hard in…
Machine learning model predicts sepsis in multidrug-resistant Pseudomonas aeruginosa infections with AUC 0.816 in external validation.
Can a Calculator Predict Deadly Infections Before They Strike?
This multicenter retrospective cohort study evaluated a machine learning-based risk prediction model in 2,001 patients with laboratory-confi…
A new computer program can spot patients at risk of severe infection days before they get sick, giving doctors a crucial head start.