Systematic review examines tumor microenvironment mechanisms in lung cancer brain metastases
New brain strategies target lung cancer before it spreads
This systematic review explores the complex mechanisms driving brain metastasis in patients with lung cancer.
Doctors are finding clever new ways to fight lung cancer that has spread to the brain without breaking the body's natural barriers
Systematic review and meta-analysis finds bacterial co-infection in 17.3% of hospitalized influenza patients
Hospital data shows high rates of bacterial co-infection in influenza patients
This systematic review and meta-analysis of 111,889 hospital-attended patients with laboratory-confirmed influenza found a pooled prevalence…
Analysis of over 111,000 patients reveals that bacterial co-infection occurs in 17.3% of hospital cases with confirmed influenza infection.
Review of Fluoroquinolone Restriction Implementation Modifications for C. difficile Prevention
Hospital plans to stop risky drugs often changed during real-world rollout
This review analyzes modifications to fluoroquinolone restriction implementation strategies from the FIRST trial across four diverse hospita…
Plans to limit risky fluoroquinolones often changed during rollout. Rural hospitals needed more tweaks than academic centers.
Preclinical study characterizes SARS-CoV-2 particles in infected cells and patient nasal swabs using flow virometry
Lab study finds new way to detect SARS-CoV-2 particles in patient samples
This preclinical research article describes the detection and characterization of single SARS-CoV-2 viral particles.
A lab study shows a method can detect SARS-CoV-2 particles directly in patient nasal swabs without extra preparation steps.
Review: Whole-genome sequencing reveals hidden S. aureus transmission in hospitals
Genome sequencing reveals hidden S. aureus spread in hospitals
This review of an observational study in two interconnected hospitals used whole-genome sequencing of 4,779 S.
Whole-genome sequencing caught 361 staph transmission events that standard surveillance missed, mostly detected only at readmission.
Narrative review discusses Risk Group 4 zoonotic virus infection and viral RNA persistence in hosts
Viruses Can Hide in Your Body Long After You Recover
This narrative review synthesizes recent evidence regarding acute infection with Risk Group 4 zoonotic viruses in disease-susceptible and na…
Hidden viral fragments may linger after recovery, causing long-term illness and sudden relapses in some patients.
Pegylated interferon alpha associated with HBsAg clearance in postpartum women with chronic HBV infection
New treatment clears hepatitis B in 3 out of 10 women after childbirth
This prospective cohort study evaluated 263 postpartum women with chronic hepatitis B virus infection and baseline HBsAg levels ≤3000 IU/mL.
A new treatment clears hepatitis B markers in nearly 30% of women after childbirth, offering fresh hope for a functional cure during a uniqu…
Chinese herbal medicine adjunct therapy reduced recovery time and MDR bacterial counts in older adults with pulmonary infection
Chinese herbal medicine may help older adults recover faster from lung infections
This retrospective cohort study evaluated Chinese herbal medicine as adjunct therapy versus conventional treatment in 372 older adults with …
Adding Chinese herbal medicine to standard care shortened hospital stays and fever for older adults with lung infections, though mortality d…
Vaginal and semen microbiota parameters in 475 infertile couples undergoing IVF
Microbes in semen and vaginal fluid do not match up for IVF success
This retrospective cohort study evaluated baseline clinical, biochemical, and microbiological parameters in 475 infertile couples undergoing…
New data shows that the germs living in a woman and man do not match up, which could change how doctors predict IVF success rates for patien…
Weekend births linked to longer antibiotic exposure in very low birth weight infants with suspected sepsis
Weekend births delay antibiotic stops for fragile newborns
This retrospective cohort study examined antibiotic exposure times in very low birth weight infants with suspected early-onset sepsis and ne…
New research shows babies born on weekends stay on antibiotics longer than those born during the work week.
Systematic review and meta-analysis of HPV knowledge prevalence and associated factors in Cameroon
Low HPV Knowledge Leaves Many Women at Risk in Cameroon
This systematic review and meta-analysis pooled data from 32 studies involving 13,457 participants in Cameroon to assess HPV-related knowled…
Most women in Cameroon lack very basic knowledge about HPV and cervical cancer risks and how it spreads.
Review of qualitative study on AFP surveillance sustainability in Ethiopia from 1996 to 2018
Ethiopia keeps polio watch despite funding cuts and hard terrain
This qualitative review examines factors affecting acute flaccid paralysis surveillance sustainability in Ethiopia between 1996 and 2018.
Ethiopia's polio watch relies on brave locals who adapt when outside funds dry up, but long-term survival needs more homegrown investment.