Review of influenza A and secondary bacterial infections identifies critical knowledge gaps
Review highlights gaps in flu and secondary infection care
This is a narrative review on influenza A virus infection, secondary bacterial infection, and nosocomial infection. The authors synthesize c…
A new review points out major missing knowledge about flu and related infections. It calls for more research to help patients.
Meta-analysis finds high fluoroquinolone resistance in E. coli causing UTIs globally
1 in 3 UTI E. coli cases now resist common antibiotics
This meta-analysis of 36 studies reports a pooled fluoroquinolone resistance prevalence of 31.09% in E. coli from UTIs. Resistance varied by…
A global review finds that nearly a third of E. coli from UTIs are resistant to key fluoroquinolone antibiotics, making infections harder to…
Meta-analysis shows carbapenems linked to higher clinical failure in OXA-48-PE infections
Doctors found higher death rates when using carbapenems for certain gut bacteria infections
This meta-analysis and review synthesizes data on carbapenem therapy for monomicrobial OXA-48-producing Enterobacterales infections. The aut…
A large review of patients with OXA-48 bacteria showed that carbapenem drugs often failed to work. Newer medicines offered better survival c…
Narrative review on COVID-19 and gut microbiome disruption and immune effects
Microbiome disruption may link SARS-CoV-2 to long-term health issues
This narrative review synthesizes evidence on COVID-19 and the intestinal microbiome. It finds SARS-CoV-2 infection can induce dysbiosis and…
A review suggests the virus may alter gut bacteria, immune signals, and brain health, highlighting a need for One Health pandemic preparedne…
Pre-infection vaccination linked to lower cardiovascular and cerebrovascular event risks in SARS-CoV-2 infected individuals
Vaccination Before Infection Cuts Heart and Stroke Risks in COVID Patients
This systematic review and meta-analysis examined the association between pre-infection COVID-19 vaccination and cardiovascular outcomes in …
Pre-infection COVID-19 vaccination significantly lowers risks of heart attacks, strokes, and other cardiovascular events in infected individ…
Meta-analysis of double-expressor lymphoma prognoses and novel therapies
Double-expressor lymphoma linked to worse survival outcomes in large study
This systematic evaluation meta-analysis of 9,808 patients with diffuse large B-cell lymphoma found double-expressor lymphoma (DEL) is assoc…
A major review finds double-expressor lymphoma patients have worse survival. New drug combinations show promise for better results.
Case report of YL205 antibody-drug conjugate in platinum-resistant ovarian carcinoma
First patient achieves complete response with new ovarian cancer drug YL205
This is a single-patient case report of a 40-year-old woman with platinum-resistant, BRCA-wildtype high-grade serous ovarian carcinoma treat…
A single patient with advanced ovarian cancer achieved a complete response after 24 weeks of treatment with YL205, a new antibody-drug conju…
Narrative review on unconventional microorganisms for non-alcoholic beer production
Unconventional microbes may help non-alcoholic beer taste like regular beer
This narrative review synthesizes published examples on using unconventional microorganisms for non-alcoholic beer production. It highlights…
A review suggests using specific non-alcoholic beer microbes can improve taste and quality compared to standard brewing methods.
Fecal Microbial Transplantation Shows Promise for Treating Gastrointestinal Acute Graft-Versus-Host Disease in Patients
Fecal transplant shows promise for gut graft-versus-host disease
A meta-analysis of 262 patients found that fecal microbial transplantation significantly improved complete response rates for gastrointestin…
A review of 262 patients found fecal transplants may improve gut graft-versus-host disease response rates compared to standard drugs.
FDA Approves Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) for HIV-1 Infection
FDA approves new once-daily pill Biktarvy for HIV treatment in adults and children.
The FDA approved Biktarvy, a three-drug combination of bictegravir, emtricitabine, and tenofovir alafenamide, for HIV-1 infection in adults …
The FDA approved Biktarvy, a once-daily pill for HIV-1 infection. It is for adults and children weighing at least 14 kg who are new to treat…
Review highlights microbial contamination risks in home-use medicines and devices for vulnerable populations
Home medicines can grow dangerous germs, review finds
This comprehensive review examines microbial contamination of home-use medicines, medical devices, cosmetics, and personal care products. Th…
A review finds everyday home medicines and devices can get contaminated with dangerous germs, putting vulnerable people at risk of serious i…
Meta-analysis shows lower prosthetic joint infection odds with cephalosporins versus non-cephalosporin prophylaxis in primary arthroplasty
Cephalosporins lower prosthetic joint infection risk in primary hip and knee replacements
This systematic review and meta-analysis evaluated single-agent cephalosporin prophylaxis against non-cephalosporin antibiotics in adults un…
A large review of over 200,000 surgeries found lower infection rates when using cephalosporins for prevention.