Cross-sectional review of mass drug administration impact on lymphatic filariasis elimination in Nepal
Mass drug administration reduces lymphatic filariasis in most Nepal districts
This cross-sectional epidemiological monitoring survey review assesses lymphatic filariasis transmission in six endemic districts of Nepal f…
A survey of over 7,000 people in Nepal found that mass drug administration lowered infection rates in most areas, though three sites still n…
Review of preclinical FH12-based Sandwich-ELISA for mucormycosis detection
Lab test shows promise for detecting mucormycosis in humans
This preclinical review evaluates an FH12-based Sandwich-ELISA for detecting mucormycosis.
A new lab method detects a specific marker for mucormycosis without cross-reacting with other fungi, offering a potential tool for diagnosis…
Nirmatrelvir-ritonavir showed no reduction in hospitalization or death within 28 days for higher-risk adults in community trials
New Study Questions Early Use of Paxlovid for Vaccinated Patients
In community-based trials involving higher-risk adults with recent SARS-CoV-2 infection, adding nirmatrelvir-ritonavir to usual care did not…
Getting vaccinated changes how your body fights the virus, and this new research shows that taking Paxlovid early might not be necessary for…
Systematic review and meta-analysis finds higher TB prevalence among people living with HIV in Africa
TB’s Hidden Link: Why HIV Changes the Risk Picture
This systematic review and meta-analysis evaluated bacteriologically-confirmed tuberculosis prevalence in 264,530 people across Southern and…
If you have HIV, your risk of missing a deadly TB diagnosis is far higher—and this study explains why that gap must close now.
Narrative review discusses natural product-based plasmid curing agents versus traditional antibiotic strategies for antimicrobial resistance
How Natural Plants Could Stop Superbugs Without Killing Them
This narrative review examines the potential of natural product-based plasmid curing agents as an alternative to traditional bactericidal an…
This approach could save antibiotics from becoming useless by forcing superbugs to surrender their defenses rather than fighting them.
Nanochitosan-coated NiTi archwires reduced bacterial CFUs versus uncoated controls in a small RCT
New Coating Slashes Cavity-Causing Bacteria on Braces
This randomized controlled trial enrolled 30 patients in an oral cavity setting.
This new wire coating could help millions with braces keep their teeth healthy.
Systematic review shows rapid diagnostic tests offer faster, cheaper HIV detection for LAI-PrEP users with low certainty evidence
Rapid tests find HIV just as well as lab tests but cost less and work faster
This systematic review and meta-analysis evaluated HIV detection strategies, including rapid diagnostic tests (RDTs), laboratory-based immun…
For people on long-acting HIV prevention, rapid tests match lab accuracy while cutting costs and speeding up treatment starts.
Remdesivir reduces COVID-19 hospitalization or death risk in high-risk outpatients
Remdesivir may cut hospitalization risk for high-risk COVID outpatients
This Bayesian reanalysis of a Phase 3 RCT in high-risk outpatients with COVID-19 found a posterior median hazard ratio of 0.13 for COVID-19-…
A reanalysis of trial data suggests remdesivir sharply lowers the chance of hospitalization or death for high-risk COVID patients treated at…
Washed microbiota transplantation in a malnourished child with resistant Klebsiella and Candida infections
Child’s stubborn lung infection cleared after gut bacteria transplant
This case report describes an 8-year-old boy with chronic malnutrition and multidrug-resistant pulmonary infections who received washed micr…
A gut bacteria transplant helped a severely malnourished child fight off a lung infection that antibiotics couldn’t touch.
Narrative review outlines VLP engineering strategies for broadly protective vaccines against multiple viral pathogens
New Vaccine Map Helps Pick Best Tools
This narrative review examines virus-like particle (VLP) engineering strategies, including genetic fusion, modular conjugation, and nucleic …
Imagine trying to fix a leaky roof with every tool in the shed.
Review of pyridylpiperazine-based inhibitors for multi-drug resistance via efflux pump inhibition
A New Trick to Make Old Antibiotics Work Again
This review evaluates pyridylpiperazine-based inhibitors and BDM-series compounds as allosteric efflux pump inhibitors (EPIs) for multi-drug…
Scientists found a way to disable bacteria's escape route, making existing drugs effective again.
Systematic review of heterotrophic bacterial bioleaching and uranium sequestration
Bacteria Could Clean Up Radioactive Waste—Here’s How
This systematic review examines heterotrophic bacterial bioleaching and sequestration of uranium.
Scientists are learning how common bacteria might one day help clean up radioactive waste safely and naturally.