FDA Approves Zithromax (azithromycin) for Community-Acquired Pneumonia and Pelvic Inflammatory Disease
FDA approves new injectable antibiotic Zithromax for two serious infections.
The FDA approved Zithromax (azithromycin) for injection for community-acquired pneumonia and pelvic inflammatory disease in adults requiring…
The FDA approved Zithromax (azithromycin) for injection to treat community-acquired pneumonia and pelvic inflammatory disease in adults who …
FDA Approves Sporanox (itraconazole) for Blastomycosis, Histoplasmosis, Aspergillosis, and Onychomycosis
FDA approves Sporanox capsules for serious fungal infections and nail fungus.
FDA approved itraconazole capsules for blastomycosis, histoplasmosis, aspergillosis (in patients intolerant/refractory to amphotericin B), a…
The FDA approved Sporanox (itraconazole) capsules to treat fungal infections like blastomycosis, histoplasmosis, and aspergillosis in certai…
5-day oral antibiotics as effective as 10-day course for pediatric GAS pharyngitis
Shorter antibiotic courses may treat strep throat in children
A systematic review and dose-response meta-analysis of 22,636 children found little to no difference in clinical outcomes between 3, 5, and …
A review of over 20,000 cases suggests a 5-day course of antibiotics is as effective as 10 days for treating strep throat in children.
FDA Approves Fetroja (cefiderocol) for Complicated UTIs and Hospital-Acquired Pneumonia
FDA approves new antibiotic Fetroja for serious bacterial infections
The FDA approved Fetroja (cefiderocol) for complicated urinary tract infections (cUTI) including pyelonephritis, and hospital-acquired bacte…
The FDA approved Fetroja (cefiderocol) to treat complicated urinary tract infections and certain pneumonia types in adults. It targets hard-…
Vonoprazan-amoxicillin dual therapy is a safe alternative to bismuth-containing quadruple therapy for H. pylori
New vonoprazan treatments show promise for clearing H. pylori infection
This multicenter randomized controlled trial of 579 H. pylori-positive patients found that vonoprazan-amoxicillin (VA) dual therapy demonstr…
Two new simplified drug combinations could offer a simpler way to clear H. pylori infections, especially for patients with certain allergies…
Cefdinir and cefprozil show superior eradication rates compared to penicillin V for Group A streptococcal pharyngitis
Certain antibiotics work better than others for strep throat
This network meta-analysis of 64 RCTs involving 23,287 participants evaluated 24 antibiotics for Group A streptococcal (GAS) pharyngitis. Th…
New data shows that while some antibiotics effectively clear strep throat, azithromycin performs poorly and carries more risks.
Evaluating Enhanced Intervention Strategies for Trachoma Elimination in Rural Ethiopian Communities
Enhanced treatment shows no extra benefit for children with trachoma
A cluster-randomized trial evaluates if adding fly control and hygiene behaviors to azithromycin dosing reduces trachoma prevalence.
A three-year study in Ethiopia found that adding extra fly control and hygiene measures did not lower infection rates more than standard dru…
Favipiravir co-administration with lopinavir-ritonavir increased favipiravir clearance by twofold in COVID-19 patients
Trial shows favipiravir and lopinavir-ritonavir do not stop COVID-19
This Phase 2a randomized, double-blind, 2x2 factorial placebo-controlled trial evaluated favipiravir and lopinavir-ritonavir in patients wit…
A new trial reveals that combining favipiravir with lopinavir-ritonavir did not show antiviral activity against the virus in patients with C…
Health insurance navigation after HIV testing was acceptable for 50.0% of eligible men
Insurance Navigation Helps Men with HIV Get Better Coverage
This randomized structural intervention involved 230 Black/African American and Hispanic/Latino men who have sex with men in Chicago. Half o…
A new study shows that offering immediate help with health insurance can successfully connect men living with HIV to better coverage and car…
Colistin-based inhalation regimens rank highest for clinical response in multidrug-resistant Acinetobacter baumannii pneumonia
Colistin Inhalation Tops for Drug-Resistant Pneumonia
This network meta-analysis of 1420 patients with multidrug-resistant Acinetobacter baumannii (MDRAB) pneumonia compared colistin, tigecyclin…
For tough pneumonia, inhaled colistin works best, but sulbactam is a good alternative without the toxicity.
Long-acting injectable antiretroviral therapy shows equivalence to oral therapy in meta-analysis of 9 RCTs
Injectable HIV therapy matches pills in global trials
This meta-analysis of 9 head-to-head RCTs (n=3208) comparing long-acting injectable (LAI) and oral antiretroviral therapies found no signifi…
A new analysis finds long-acting injectable HIV meds work as well as daily pills, but results may vary by region.
Cefmetazole or flomoxef linked to higher 14-day mortality vs carbapenems in ESBL-PE bacteremia
Trial Shows Carbapenems May Outperform Other Antibiotics for Bacteremia
This meta-analysis of 975 adults with ESBL-producing Enterobacterales bacteremia found that cefmetazole or flomoxef was associated with sign…
New data suggests carbapenem antibiotics may offer better early survival rates than cefmetazole or flomoxef for patients with specific blood…