Review of cross-sectional study on tongue swab Xpert MTB/RIF Ultra diagnostic accuracy in Vietnamese adolescents
Tongue Swabs Could Spot TB in Teens Without Coughing
This cross-sectional diagnostic accuracy review evaluates tongue swab testing with Xpert MTB/RIF Ultra in adolescents aged 10-19 in Vietnam.…
A painless tongue swab may help find tuberculosis in teens who can’t produce sputum, offering hope for earlier and easier diagnosis in hard-…
Protocol outlines AI/ML approaches to identify TB transmission drivers and treatment failure factors in Uganda.
AI tools spot silent TB risks before symptoms appear in Uganda
This study protocol describes a planned investigation into Tuberculosis and HIV/TB coinfection in Kampala city, Uganda. The authors propose …
Smart computer programs can find hidden tuberculosis risks in households before anyone feels sick or fails their medicine.
Observational study evaluates clinical prediction models for dengue, chikungunya, and Oropouche fever in Brazil
New Tool Helps Doctors Tell Dengue, Chikungunya, and Oropouche Fever Apart
This observational study analyzed surveillance data from Espirito Santo state, Brazil, involving 465,280 observations to assess clinical pre…
A new online tool can tell apart dengue, chikungunya, and Oropouche fever using simple symptoms, helping doctors make faster, more accurate …
Survey finds physicians show stronger intergroup bias than public on vaccines
Doctors Show Strong Bias Against Vaccine-Hesitant Patients
This review of an online survey in Japan involving 492 physicians and 5,252 members of the general public found that physicians exhibited hi…
Doctors often see themselves as targets of vaccine anger, but new data shows they also hold strong bias against patients who question vaccin…
Review Highlights Epigenetic Reprogramming Over Genetic Mutations in Cancer-Associated Fibroblasts Function
Hidden Cancer Helpers Drive Growth Without DNA Changes
This narrative review examines cancer-associated fibroblasts within the tumor microenvironment, focusing on epigenetic modifications versus …
New research reveals hidden cancer helpers use chemical switches to grow tumors, offering fresh targets for future treatments.
Retrospective analysis of P. aeruginosa persistence in hospital water systems among pediatric patients in England
One hospital water system kept bacteria alive for eight years
This retrospective analysis reviews environmental and clinical P. aeruginosa isolates from a large tertiary children's hospital in England b…
A single water system in an English children's hospital held onto harmful bacteria for eight years, showing how hard it is to clear these ge…
Metformin, fluvoxamine, or ivermectin for non-hospitalized COVID-19 adults in a Phase 3 trial
Metformin Cuts Long Covid Risk by 40%
This randomized controlled trial in 1323 non-hospitalized adults with SARS-CoV-2 infection evaluated metformin, fluvoxamine, or ivermectin v…
A common diabetes pill taken early in Covid infection cuts the odds of developing long-term symptoms by 40%, offering new hope for millions.
Community-based intervention reduces antibiotic use in Burkina Faso and DRC
New Plan Cuts Dangerous Antibiotic Use in African Villages
In this cluster randomised controlled trial across 44 villages in Burkina Faso and Democratic Republic of Congo, a community-based behaviour…
A simple community plan successfully lowered the use of strong antibiotics in rural Africa.
Systematic review and meta-analysis of Salmonella prevalence and AMR in global wild birds
Wild Birds Are Picking Up Drug-Resistant Germs—And It’s Getting Worse
This systematic review and meta-analysis synthesizes data on Salmonella prevalence and antimicrobial resistance (AMR) patterns across global…
Wild birds are becoming living carriers of drug-resistant bacteria, and that poses a growing risk to human health worldwide.
PPV and voriconazole for endogenous fungal endophthalmitis outbreak improves visual acuity
Contaminated IVs Cause Sudden Blindness in Healthy Adults
This retrospective case series evaluated 26 eyes of 17 immunocompetent patients with endogenous fungal endophthalmitis following a rural cli…
Healthy adults lost vision after contaminated IV infusions, but early surgery and antifungals helped save sight in most cases.
Review Analytical Performance of Multiplex PCR Assays for Tuberculosis and Drug Resistance
New test spots TB and drug resistance in one quick scan
This review evaluates the comprehensive analytical performance of multiplex open real-time PCR assays for tuberculosis and drug resistance i…
A new lab test finds TB and drug resistance in one quick scan, but it misses some rare germs that need more study.
Algorithm development study validates FindPart-w model for identifying SARS-CoV-2 lineage groups in the US
New tool sorts virus variants by how fast they spread
This algorithm development and validation study evaluates the FindPart-w algorithm and constrained RelRe model against the Pango lineage nom…
A new math tool groups virus variants by how fast they spread instead of just looking at their genetic makeup alone.