Machine learning model aids early risk stratification for carbapenem-resistant Pseudomonas aeruginosa infection
New tool helps identify resistant bacteria early in hospital patients
This retrospective cohort study evaluated a clinico-laboratory machine-learning model based on routine complete blood count parameters in pa…
A new tool uses routine blood tests to predict dangerous antibiotic resistance in hospital patients before final lab results arrive.
Whole-genome sequencing of 108 CRKP isolates from South China reveals ST11 dominance and emerging hvCRKP
Genomic analysis reveals resistance patterns in carbapenem-resistant Klebsiella pneumoniae from South China hospitals
This retrospective molecular epidemiology study characterized 108 carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates from multiple h…
Genomic analysis of South China hospitals found a new KPC-12 variant in carbapenem-resistant bacteria, alongside mutations that make these g…
Meta-analysis of antiretroviral therapy virologic suppression in HIV-positive pregnant and lactating women in Africa
New review shows HIV treatment success varies by age and adherence
This systematic review and meta-analysis evaluated virologic suppression among 304,883 HIV-positive pregnant and lactating women in Africa.
In Africa, HIV treatment success for women varies by age and medicine adherence, with only 60.92% reaching the ideal undetectable viral load…
Pre-infection symptoms and functional status associated with long COVID risk in 65,464 U.S. adults
Did you know older age and female sex increase long COVID risk?
This retrospective cohort study of 65,464 U.S.
Older age, female sex, and lower mental health before infection raise long COVID risk, while having more pre-existing symptoms also increase…
Narrative review discusses extracellular vesicles versus traditional nanocarriers for drug and vaccine delivery
Review compares extracellular vesicles to traditional nanocarriers for drug delivery
This narrative review examines the potential of extracellular vesicles (EVs) compared to traditional nanocarriers like lipid nanoparticles f…
Tiny natural particles called extracellular vesicles show promise as next-generation carriers for delivering medicines and vaccines into the…
HIV status and ART exposure associated with altered skin microbiome diversity and composition in Indonesia
Does HIV change the bacteria living on your skin, and does treatment help?
This prospective observational study in Indonesia enrolled 244 participants, including people living with HIV, HIV-ART-naïve individuals, an…
HIV changes the bacteria living on your skin, and treatment helps bring those levels closer to normal.
Review of topical phage therapy for wounds and burns notes dosing standardization gaps
Why Topical Phage Therapy Needs a New Plan
This review examines the use of topical phage therapy for wound and burn conditions.
Topical phage therapy works best when doctors standardize doses and delivery methods to break through bacterial shields in tough wounds and …
Integrative review finds fitness consequences of ESBL and AmpC resistance plasmids in E. coli are assay-dependent
Why Resistance Spreads So Fast
This integrative review synthesizes 40 studies on fitness consequences of plasmid-mediated ESBL and AmpC resistance in E.
Tiny DNA USB drives let gut bacteria swap antibiotic resistance genes, causing infections to spread faster than ever before.
Narrative review summarizes drug classes for coronavirus infection, including small molecules and Traditional Chinese Medicine
What small and large drugs might do for coronavirus infections remains unclear in this review
This narrative review surveys drug classes like small-molecule drugs, macromolecular drugs, peptides, polymers, and Traditional Chinese Medi…
Coronavirus treatments range from small-molecule drugs to Traditional Chinese Medicine, but this review finds the evidence remains incomplet…
Narrative review examines carbapenem-resistant E. coli and One Health approach in AMR governance
Review offers theoretical support for managing carbapenem-resistant E. coli in public health
This narrative review explores carbapenem-resistant Escherichia coli and its implications for antimicrobial resistance governance.
This narrative review examined carbapenem-resistant Escherichia coli, a type of bacteria that resists strong antibiotics.
Narrative review suggests combination regimens over vancomycin monotherapy for Elizabethkingia meningoseptica infections
Is vancomycin alone safe for a rare infection that might actually need a stronger team approach?
This narrative review addresses Elizabethkingia meningoseptica infections, noting that frequent misidentification between E.
Doctors should combine vancomycin with other antibiotics instead of using it alone to treat rare Elizabethkingia infections, because relying…
Ugandan malaria patients with PfKelch13 mutant parasites showed no increased gametocyte production or mosquito transmission
Uganda Malaria Study: Does Resistance Stop Spreading?
This cohort study evaluated 235 Ugandan malaria patients at Kalongo Hospital for PfKelch13 mutations (C469Y or A675V) compared to wild-type …
Resistant malaria parasites in Uganda do not spread more easily to mosquitoes, offering hope that current treatments remain effective agains…