Serum N-myc and STAT interactor (NMI) levels predict 30-day mortality and septic shock in adult sepsis patients
New Blood Marker Spots Deadly Sepsis Early
This cohort study of 399 adult patients diagnosed with sepsis evaluated serum N-myc and STAT interactor (NMI) concentrations.
A newly studied blood protein can spot which sepsis patients are most at risk — long before their condition crashes.
Molecular epidemiology study of rifampicin-resistant TB in Vietnam shows high resistance to other drugs
Vietnam’s TB Crisis Hides a Dangerous Pattern
This molecular epidemiology study analyzed 252 rifampicin-resistant TB isolates from Vietnam using whole genome sequencing.
A hidden pattern in Vietnam’s tuberculosis cases reveals most drug-resistant strains also resist other key medicines, changing how doctors m…
Electronic health record study links prior antimicrobial resistance to bacteraemia in cancer patients
Prior Antibiotic Resistance Linked to Higher Bacteraemia Risk in Cancer Patients
This electronic health record study analyzed 2752 adults with cancer diagnostic codes in Oxfordshire, UK, between 2015 and 2025.
Past antibiotic resistance in cancer patients strongly predicts future bloodstream infections, with specific cancer types increasing odds of…
Mathematical modelling review projects TB incidence and mortality declines in South Africa adults by 2030
New TB Test Could Cut Cases in Half
This mathematical modelling review analyzes Tuberculosis and HIV dynamics in South African adults using 1000 parameter combinations.
A simple swab test could stop TB from spreading by finding cases faster, especially in places where people struggle to get diagnosed.
Review of cross-sectional study on tongue swab Xpert MTB/RIF Ultra diagnostic accuracy in Vietnamese adolescents
Tongue Swabs Could Spot TB in Teens Without Coughing
This cross-sectional diagnostic accuracy review evaluates tongue swab testing with Xpert MTB/RIF Ultra in adolescents aged 10-19 in Vietnam.
A painless tongue swab may help find tuberculosis in teens who can’t produce sputum, offering hope for earlier and easier diagnosis in hard-…
Protocol outlines AI/ML approaches to identify TB transmission drivers and treatment failure factors in Uganda
AI tools spot silent TB risks before symptoms appear in Uganda
This study protocol describes a planned investigation into Tuberculosis and HIV/TB coinfection in Kampala city, Uganda.
Smart computer programs can find hidden tuberculosis risks in households before anyone feels sick or fails their medicine.
Observational study evaluates clinical prediction models for dengue, chikungunya, and Oropouche fever in Brazil
New Tool Helps Doctors Tell Dengue, Chikungunya, and Oropouche Fever Apart
This observational study analyzed surveillance data from Espirito Santo state, Brazil, involving 465,280 observations to assess clinical pre…
A new online tool can tell apart dengue, chikungunya, and Oropouche fever using simple symptoms, helping doctors make faster, more accurate …
Survey finds physicians show stronger intergroup bias than public on vaccines
Doctors Show Strong Bias Against Vaccine-Hesitant Patients
This review of an online survey in Japan involving 492 physicians and 5,252 members of the general public found that physicians exhibited hi…
Doctors often see themselves as targets of vaccine anger, but new data shows they also hold strong bias against patients who question vaccin…
Review Highlights Epigenetic Reprogramming Over Genetic Mutations in Cancer-Associated Fibroblasts Function
Hidden Cancer Helpers Drive Growth Without DNA Changes
This narrative review examines cancer-associated fibroblasts within the tumor microenvironment, focusing on epigenetic modifications versus …
New research reveals hidden cancer helpers use chemical switches to grow tumors, offering fresh targets for future treatments.
Retrospective analysis of P. aeruginosa persistence in hospital water systems among pediatric patients in England
One hospital water system kept bacteria alive for eight years
This retrospective analysis reviews environmental and clinical P.
A single water system in an English children's hospital held onto harmful bacteria for eight years, showing how hard it is to clear these ge…
Metformin, fluvoxamine, or ivermectin for non-hospitalized COVID-19 adults in a Phase 3 trial
Metformin Cuts Long Covid Risk by 40%
This randomized controlled trial in 1323 non-hospitalized adults with SARS-CoV-2 infection evaluated metformin, fluvoxamine, or ivermectin v…
A common diabetes pill taken early in Covid infection cuts the odds of developing long-term symptoms by 40%, offering new hope for millions.
Community-based intervention reduces antibiotic use in Burkina Faso and DRC
New Plan Cuts Dangerous Antibiotic Use in African Villages
In this cluster randomised controlled trial across 44 villages in Burkina Faso and Democratic Republic of Congo, a community-based behaviour…
A simple community plan successfully lowered the use of strong antibiotics in rural Africa.