Digital chest radiography with CAD shows variable sensitivity for asymptomatic tuberculosis in South African adults
Digital scans miss many silent tuberculosis cases in South Africa adults
This cohort study evaluated digital chest radiography (dCXR) read by blinded human readers and qXR CAD in 1353 adults in South Africa.
New data from South Africa shows digital scans and computer tools miss many silent tuberculosis cases, raising questions about current scree…
Shorter antibiotic courses may match longer ones for canine pneumonia, but evidence is weak
Shorter antibiotic courses work just as well as longer ones for dog pneumonia
This systematic review and meta-analysis of 74 dogs found no significant difference in treatment success between shorter (10-14 days) and lo…
A new analysis suggests shorter antibiotic courses may treat dog pneumonia just as well as longer ones, though evidence for cats is missing.
Systematic Review Finds No BV Recurrence Reduction With Male Partner Treatment
Combined treatment does not lower bacterial vaginosis recurrence rates
This systematic review and meta-analysis of 953 couples found that treating male sexual partners of women with bacterial vaginosis did not s…
A large review of 953 couples found that treating male partners alongside women did not reduce bacterial vaginosis recurrence compared to tr…
Narrative review of Shenfu Injection for sepsis-induced gastrointestinal injury and septic shock
A Chinese herbal therapy may protect the gut during septic shock
This narrative review examines Shenfu Injection for sepsis-induced acute gastrointestinal injury and septic shock.
A traditional Chinese herbal blend may help protect the gut during septic shock, offering a new angle on a deadly complication that often go…
Systematic review and meta-analysis finds subtyping methods linked to HIV recombinant form prevalence
New HIV variants hide in plain sight due to testing limits
This systematic review and meta-analysis of over 400 peer-reviewed studies examines HIV subtype prevalence and subtyping methodologies.
Scientists found that how we test for HIV changes what we think we know about new virus forms.
Meta-analysis shows antibiotics and TCM are effective for bovine mastitis in dairy cows
Traditional Chinese Medicine shows promise for treating cow mastitis
This meta-analysis reviews efficacy data from nine antibiotic studies and ten Traditional Chinese Medicine (TCM) studies in dairy cows with …
A review of nine antibiotic studies and ten Traditional Chinese Medicine studies found both treatments work for bovine mastitis.
Meta-analysis shows linezolid-containing regimens for multidrug/rifampicin-resistant tuberculosis
Linezolid helps treat drug resistant tuberculosis
This meta-analysis of 3019 patients evaluates the efficacy and safety of linezolid-containing regimens compared to standard of care for…
New evidence shows that adding linezolid to treatment helps patients with drug resistant tuberculosis achieve better health outcomes.
Nirmatrelvir/Ritonavir in Breast Milk: Low Infant Exposure in Lactating Women
Paxlovid levels low in breast milk, early study finds
This Phase 1 open-label study in 8 healthy lactating women found that nirmatrelvir/ritonavir concentrations in breast milk were consistently…
A small study finds that nirmatrelvir/ritonavir (Paxlovid) passes into breast milk at low levels, suggesting minimal infant exposure.
Islatravir and lenacapavir fixed-dose combination shows similar bioavailability to single agents in healthy volunteers
New HIV pill works with or without food in early safety tests
This open-label phase 1 study enrolled 93 people without HIV to assess the oral relative bioavailability and safety of a fixed-dose combinat…
A new HIV pill containing islatravir and lenacapavir showed similar drug levels whether taken with food or on an empty stomach, supporting f…
Phase 1 study traces ainuovirine metabolism and excretion in healthy men
A single dose of oral ainuovirine clears the body within two days in healthy men
This phase 1 open-label study in 6 healthy men examined the pharmacokinetics and mass balance of a single dose of radiolabelled ainuovirine.
A single dose of oral ainuovirine clears the body within two days in healthy men, with most of the drug leaving unchanged through urine and …
Observational study assesses MiniDock MTB diagnostic accuracy against Xpert in Indonesian TB patients
New TB test shows promise in Indonesia trial
This observational study evaluated the diagnostic accuracy of MiniDock MTB on sputum swabs compared to Xpert MTB/RIF Ultra and liquid cultur…
A new TB test called MiniDock MTB accurately detected TB in adults, but sensitivity dropped in children and low-burden cases.
Review finds higher ambient temperature linked to lower viral gastroenteritis rates in children
Hotter weather may lower the chance of viral stomach bugs in children
This secondary analysis of a prospective multisite study reviews the association between environmental exposures and viral gastroenteritis i…
Higher temperatures were linked to fewer viral stomach bugs in children, suggesting weather patterns matter for health.