Observational cohort study on SARS-CoV-2 evolution in immunocompromised patients
Long COVID Virus Changes Shape Inside Severely Ill Patients, Study Finds
This observational cohort study analyzed longitudinal SARS-CoV-2 genomes from 91 immunocompromised patients with COVID-19.
When the virus lingers too long in very sick patients, it changes in unpredictable ways, highlighting the need for stronger treatments.
Modelling analysis review estimates TB cases and deaths averted by screening in ten Asian countries
A $12 Billion Plan to Save Millions from Tuberculosis
This modelling analysis review evaluates the epidemiological impact and cost implications of scaling up tuberculosis screening across ten hi…
AI scans in communities could save millions of lives by finding silent tuberculosis cases in ten high-risk Asian countries before they sprea…
Observational serological model in Malawi shows rapid SARS-CoV-2 antibody waning and urban-rural differences
Malawi Study Rewrites Rules of COVID Immunity
This observational study used serological modelling to reconstruct SARS-CoV-2 infection histories in unvaccinated Malawian adults.
In Malawi, natural immunity fades fast, with antibodies dropping to 5% after one year, so vaccines remain essential for lasting protection.
Selective Decontamination of the Digestive Tract showed no mortality benefit over standard care in mechanically ventilated patients
A Common ICU Infection Strategy Fails Its Biggest Test
This randomized trial involving 9,289 critically ill patients across 26 ICUs in Australia and Canada evaluated Selective Decontamination of …
A massive ICU trial found that wiping out gut bacteria in ventilated patients reduced infections but did not save more lives.
Adjuvanted RSV vaccine shows efficacy against RSV disease in older adults with comorbidities
One RSV Shot Protects High-Risk Older Adults for Three Full Seasons
This post-hoc analysis of a phase 3 trial evaluated an adjuvanted RSVPreF3 dose in medically stable adults aged 60 and older with underlying…
One RSV shot cuts illness risk by 63% to 75% for older adults with COPD, asthma, diabetes, or obesity over three full seasons.
Phase Ia trial of RH5.1 protein with Matrix-M adjuvant in malaria-naive UK adults showed safety and similar immunogenicity across two booster regimens
A Malaria Vaccine Candidate Holds Strong — Even With a Smaller Booster Dose
This Phase Ia clinical trial evaluated the safety and immunogenicity of RH5.1 soluble protein with Matrix-M adjuvant in malaria-naive UK adu…
A malaria vaccine candidate produced strong immune responses even when the final booster dose was cut in half, potentially helping extend va…
Random forest model predicts pediatric varicella encephalitis with excellent performance in a retrospective analysis
A Simple Checklist Could Catch the Most Dangerous Chickenpox Complication Early
This retrospective analysis evaluated a random forest model for predicting pediatric varicella encephalitis in 201 children.
A new AI tool predicts dangerous chickenpox brain complications in kids with 95% accuracy using just six simple symptoms like rash duration …
Monoclonal stool antigen test shows high accuracy for H. pylori detection in chronic atrophic gastritis patients
A Simple Stool Test Spots a Dangerous Stomach Bug Without a Scope
This prospective primary care study evaluated 287 patients with chronic atrophic gastritis (CAG) using a monoclonal stool antigen test (SAT)…
A simple stool test spots dangerous stomach bugs in people with chronic gastritis, performing even better when the stomach is most at risk.
EBNA1 SeroStrip-HT shows high accuracy for nasopharyngeal carcinoma risk assessment in a nested case-control study
A Blood Test May Spot a Rare Cancer Years Before Symptoms Appear
This nested case-control study evaluated the EBNA1 SeroStrip-HT in prospective cohorts from Singapore and Shanghai, China.
A simple blood test can spot a rare throat cancer up to four years before symptoms appear, giving doctors time to treat it early.
Serum cutoff values for MPXV antigens established in a DRC cohort of 134 individuals
How Scientists Are Learning to Read Mpox Immunity in the Hardest-Hit Places
This cohort study of 134 individuals in the Democratic Republic of the Congo established antigen-specific serological cutoff values to diffe…
A new three-antigen blood test can identify past mpox infections in Central Africa, helping track immunity in the hardest-hit regions.
Hypervirulent Klebsiella pneumoniae linked to higher abscess risk and longer hospital stays in bloodstream infections
The "Super" Bacteria Causing Hospital Infections Doctors Struggle to Clear
A retrospective cohort study of 207 K. pneumoniae bloodstream infection episodes at a Japanese tertiary hospital found that hypervirulent st…
A specific aggressive form of hospital bacteria causes abscesses in patients six times more often than the common strain and doubles their h…
Methodological review assesses phenotypes for classifying respiratory viruses in English health data
How Doctors Track RSV, Flu, and COVID When Tests Aren't Always Done
This methodological review evaluates phenotypes for classifying respiratory viruses like RSV, influenza, and COVID-19 in English coded healt…
Coded health records can now identify RSV, flu, and COVID-19 outbreaks without lab tests, helping public health agencies track disease trend…