MRgLITT provides comparable QALYs to open resection for children with drug-resistant focal epilepsy
Laser surgery shows better survival for children with drug-resistant epilepsy
This systematic review utilizes a Markov decision analytic model to compare MRgLITT and open resective surgery against medical management in…
A new analysis suggests laser surgery can offer a 4.6 year survival advantage over medical management for children with certain types of epi…
Berberine identified as potential Alzheimer's treatment targeting HMGCR in astrocyte-driven model
New research identifies a potential target for Alzheimer's disease
This guideline presents a computational analysis identifying an autolysosome-astrocyte-associated diagnostic model for Alzheimer's disease, …
Scientists identified a specific gene as a key driver of Alzheimer's and found that the compound berberine may help target it.
FDA Approves Leqembi Iqlik (lecanemab) for Alzheimer's Disease
FDA approves new Alzheimer's drug Leqembi Iqlik with flexible dosing options.
FDA approved Leqembi Iqlik (lecanemab) for Alzheimer's disease. Treatment should be initiated in patients with mild cognitive impairment or …
The FDA approved Leqembi Iqlik (lecanemab) for early Alzheimer's disease. It is for people with mild cognitive impairment or mild dementia. …
Early tirofiban improves functional outcomes in non-DM ischemic stroke patients but not in DM
Trial shows stroke treatment effects vary for patients with diabetes
This post-hoc analysis of a randomized controlled trial involving 832 patients with acute ischaemic noncardioembolic stroke found that early…
A new look at trial data suggests a common stroke medication works better for some patients than others based on their diabetes status.
Trial protocol for intra-arterial alteplase in anterior circulation large-vessel occlusion ischaemic stroke
Trial Plans to Test Intra-arterial Alteplase for Ischaemic Stroke
This Phase 3 randomized controlled trial protocol describes the evaluation of intra-arterial thrombolysis with alteplase in patients with ac…
A new large-scale study in France aims to determine if injecting alteplase directly into a blocked artery improves outcomes for stroke patie…
tDCS improves lower limb motor function and walking distance in patients with multiple sclerosis
Trial Shows Brain Stimulation Improves Lower Limb Function in MS
This meta-analysis of 299 individuals with multiple sclerosis found that transcranial direct current stimulation (tDCS) significantly improv…
Brain stimulation may improve lower limb movement and walking distance for people with multiple sclerosis, but results vary by treatment int…
TBP expansion in SCA17 can cause dementia-like symptoms and requires etiological reconsideration
New Diagnosis for Dementia Patients with Spinocerebellar Ataxia Type 17
This case report and focused literature review describes a patient with SCA17 presenting as dementia, highlighting the need for genetic test…
A new look at dementia cases may reveal an underlying genetic condition called spinocerebellar ataxia type 17.
Evaluating the Efficacy of GLP-1 Receptor Agonists in Patients with Parkinson's Disease
GLP-1 medications show no motor benefit for Parkinson's patients
A meta-analysis reveals that GLP-1 receptor agonists provide no significant motor or non-motor benefits for patients with idiopathic Parkins…
New data suggests GLP-1 receptor agonists do not improve movement or non-motor symptoms in people with Parkinson's disease.
Combined tDCS and mirror therapy improves upper limb function and activities of daily living after stroke
Brain Zaps Plus Mirror Therapy Boost Stroke Recovery
This meta-analysis of 454 patients indicates that combining transcranial direct current stimulation (tDCS) and mirror therapy (MT) significa…
Combining brain stimulation with mirror therapy may help stroke survivors regain arm and hand function.
Mechanical thrombectomy increases parenchymal hematoma risk but maintains better functional outcomes
Trial shows mechanical thrombectomy improves outcomes despite higher bleeding risk
This post hoc analysis of a randomized controlled trial involving 253 patients with anterior circulation stroke found that mechanical thromb…
Mechanical thrombectomy can improve recovery after a stroke, even though it is linked to a higher rate of certain types of brain bleeding.
Adaptive immune signatures and T cell infiltration characterize pathology in Alzheimer's, Parkinson's, and Lewy Body dementia
Adaptive Immune Signatures Linked to Alzheimer's and Parkinson's Disease
This mini review synthesizes evidence regarding adaptive immune remodeling and T cell responses in neurodegenerative dementias. The authors …
New research highlights how specific immune cell activity may play a role in the progression of Alzheimer's, Parkinson's, and Lewy body deme…
Operator device-selection preference did not correlate with superior first-pass effect rates in stroke thrombectomy
More experience improves stroke treatment success but not doctor preference
This retrospective analysis of prospective data involving 1405 patients undergoing thrombectomy found that operator preference for a specifi…
Doctors who perform more stroke procedures achieve better results, even though their personal preference for a specific technique does not c…