CZTL capsule therapy study design for acute ischemic stroke patients not eligible for IVT or with early deterioration
New Stroke Pill Could Help Patients Missed by Standard Care
This randomized, double-blind, placebo-controlled, multicenter clinical study design involved 1,208 eligible patients with acute ischemic st…
A large new study is testing if a specific herbal capsule can help stroke patients who miss out on standard treatments.
Brain atrophy patterns evolve from lower brainstem in spinocerebellar ataxia type 1 cohort study
New MRI maps show exactly how SCA1 eats away at the brain
This cohort study examined brain atrophy patterns in 152 SCA1 participants and 131 healthy controls across seven sites.
New brain scans reveal a specific pattern of damage in SCA1 that starts lower down and moves up, changing how doctors track the disease.
Sex hormone traits linked to Alzheimer's risk in sex-specific Mendelian randomization study
Women and men face different Alzheimer's risks linked to specific hormones
A cohort study using Mendelian randomization found that bioavailable testosterone in women and SHBG in men are associated with lower Alzheim…
New science shows specific hormones protect women and men from Alzheimer's disease in unique ways that doctors must consider.
CSF α-synuclein SAA detects Lewy body dementia with 95% sensitivity in multicenter cohort
Researchers find new test spots Lewy body dementia
This prospective cohort study of 398 patients from memory clinics found that CSF α-synuclein seed amplification assay (SAA) had 95% sensitiv…
A new blood and spinal fluid test accurately identifies Lewy body dementia, even when Alzheimer’s is also present, helping clarify diagnosis…
Standardized P-VEEG recordings and SEPs show polygraphic patterns in 73 pediatric patients with hyperkinetic movement disorders
New Test Helps Sort Out Confusing Kids' Movement Issues
This cohort study of 73 pediatric patients with hyperkinetic movement disorders at Besta Neurological Institute assessed standardized P-VEEG…
Doctors can now see hidden patterns in a child's movements that look confusing to the naked eye.
VOR gain recovery and saccade patterns in acute unilateral vestibulopathy over 12 months
Your Brain’s Balance System Can Retrain Itself — Here’s How
This prospective longitudinal study in 43 patients with acute unilateral vestibulopathy tracked vestibulo-ocular reflex (VOR) gain and sacca…
Imagine waking up dizzy, the room spinning, and every head turn making you feel sick.
Spanish RSBQ Validation in 51 Latin American Rett Syndrome Caregivers
New Spanish Tool for Rett Syndrome Improves Care for Thousands
This observational linguistic validation study assessed a Spanish translation of the Rett Syndrome Behaviour Questionnaire among 51 Spanish-…
A Spanish-language behavior checklist for Rett Syndrome now matches the English version, helping Spanish-speaking families get more accurate…
Bridging IV Thrombolysis Plus EVT vs EVT Alone in Late-Window Anterior Circulation Stroke
Why Giving Two Treatments Doesn't Always Help
This retrospective analysis of a prospective registry compared bridging intravenous thrombolysis plus endovascular thrombectomy with direct …
Adding a second drug before the clot-removal procedure offers no clear benefit for most patients in the late window.
Review synthesizes observational data linking earlier menopause to accelerated aging and dementia risk in postmenopausal women
Early Menopause Tied to Faster Brain Aging
This narrative review synthesizes data from the UK Biobank (n=15,012) and the Women's Health Initiative Long Life Study (n=1,210).
Women who go through menopause early may face faster brain aging, linked to higher dementia risk, a new analysis of over 15,000 women reveal…
Prospective study of 7T MRI black rims in hereditary Dutch-type cerebral amyloid angiopathy
Black Rims on Scans Mean Iron Buildup After Bleeding
This prospective observational study examined 20 patients with hereditary Dutch-type cerebral amyloid angiopathy (D-CAA) at Leiden Universit…
Imagine looking at a brain scan and seeing dark rings around tiny blood vessels.
Cerebral small vessel disease burden predicts cognitive recovery after stroke
Brain Scan Score Predicts Stroke Memory Recovery
This observational study of 65 early subacute stroke survivors found that a lower composite measure of cerebral small vessel disease (cCSVD)…
A simple brain scan taken soon after a stroke can now help predict whether a person will regain memory and thinking skills — a shift that co…
Simulation study of frontier AI models analyzing 10,000 synthetic Multiple Sclerosis cases reveals variable diagnostic safety
AI Doctors Miss Critical Clues in 10,000 Tests
This simulation study reviewed 10,000 synthetic Multiple Sclerosis cases analyzed by frontier artificial intelligence models against ground-…
Imagine walking into a clinic with a severe headache.