Protocol for a review on neurosurgical intervention versus conservative management in older adults with traumatic brain injury
This plan guides surgery choices for older adults with brain injuries to improve care
This is a protocol for a planned review on traumatic brain injury in adults aged 65 years and older. It will compare neurosurgical intervent…
This document outlines a plan to study surgery for older adults with brain injuries. It will compare surgical treatment against non-surgical…
Stroke scale expansions improve posterior circulation deficit detection
New tools help doctors spot brain issues in the back part of the head better than old methods
Expanded NIHSS and posterior-specific tools enhance sensitivity for posterior stroke deficits, aiding bedside assessment and prognostic stra…
Doctors are using new scales to find strokes in the back of the brain. These tools work better than the standard ones used today.
Narrative review offers qualitative synthesis without reported quantitative outcomes or safety data
Review explores how lifestyle changes can lower heart disease risk
This narrative review synthesizes existing literature on a topic where specific populations, interventions, and outcomes were not reported. …
A new review suggests healthy habits may cut heart disease risk by about 30%. It highlights diet, exercise, and sleep.
FDA Approves Mavenclad (cladribine) for Relapsing Forms of Multiple Sclerosis
FDA approves new multiple sclerosis drug Mavenclad for relapsing forms
The FDA approved Mavenclad (cladribine) for relapsing forms of MS, including relapsing-remitting and active secondary progressive disease, i…
The FDA approved Mavenclad (cladribine) for adults with relapsing forms of multiple sclerosis (MS), including relapsing-remitting and active…
Narrative review proposes integrative monitoring framework for intracerebral hemorrhage
New monitoring tools may help tailor iron treatments for brain bleeding
This narrative review critiques current monitoring strategies for intracerebral hemorrhage and proposes a multidimensional integrative frame…
Current ways to track brain bleeding often miss the complex chemical changes happening inside. A review suggests better tools could help doc…
Repetitive transcranial magnetic stimulation shows promise for improving cognition and executive function in patients with mild cognitive impairment
Magnetic stimulation may boost thinking skills in mild cognitive impairment
A systematic review and meta-analysis of 532 patients with mild cognitive impairment found that repetitive transcranial magnetic stimulation…
A review of five studies found that repetitive magnetic stimulation improved thinking and memory in people with mild cognitive impairment, t…
Individual patient data meta-analysis links blood neurofilament light chain levels to ischemic stroke outcomes
High blood NfL levels predict worse outcomes after ischemic stroke
This individual patient data meta-analysis evaluated blood neurofilament light chain (NfL) levels in 2872 adult patients within 30 days afte…
A meta-analysis of 2,872 patients found that higher blood neurofilament light chain levels within days of an ischemic stroke predict greater…
Meta-analysis of Mendelian randomization suggests GLP-1 receptor agonism lowers vascular dementia risk
Genetic data suggests GLP-1 drugs may lower vascular dementia risk
This meta-analysis of Mendelian randomization studies evaluated the association between GLP-1 receptor agonism and dementia risk using genet…
New genetic evidence hints that GLP-1 receptor agonists might lower the risk of vascular dementia, but results for Alzheimer's disease remai…
Review of 2-AG and benzodiazepines for anxiety disorders highlights mechanistic gaps
New review questions how 2-AG might help anxiety disorders in humans
This narrative review synthesizes preclinical evidence on 2-arachidonoylglycerol and benzodiazepines for anxiety disorders. The authors note…
A new review suggests 2-AG could help anxiety, but lab tests used unrealistic doses and human proof is still missing.
Meta-analysis links mitochondrial polygenic score to alpha-synuclein seeding in LRRK2-related Parkinson's disease
A new test detects Parkinson's linked to a specific gene variant in most cases
This meta-analysis evaluates the association between CSF-based alpha-synuclein seed amplification assay (aSyn SAA) and LRRK2-related Parkins…
A new blood test found alpha-synuclein in 80 percent of people with Parkinson's linked to a specific gene variant, helping distinguish this …
Review of ivermectin MDA for onchocerciasis and hookworm co-infections in endemic regions
Ivermectin helps clear hookworm even when people also carry river blindness
This narrative review synthesizes evidence on preventative chemotherapy and Mass Drug Administration with ivermectin for onchocerciasis and …
A review shows ivermectin treatment improves outcomes for people infected with both river blindness and hookworm, though more data on immune…
Comprehensive review examines nano-adjuvant technologies for poultry vaccines globally
Nano-adjuvants may boost poultry vaccines and protect birds from new viruses
This comprehensive review evaluates nano-adjuvant technologies, including lipid nanoparticles and polymeric systems, compared to existing li…
A global review suggests nano-adjuvant technologies could make poultry vaccines safer, more effective, and easier to use against emerging vi…