Obesity in older adults lowers Alzheimer's risk while underweight status and weight loss increase it
Obesity protects older adults from Alzheimer's risk, but not younger ones
This systematic review and meta-analysis examined thirty-eight studies on anthropometric measures in individuals with Alzheimer's disease ri…
A meta-analysis of thirty-eight studies found that obesity lowers Alzheimer's risk in people over sixty, while increasing risk in those unde…
Ceramides emerge as key players in Alzheimer's pathology but therapeutic targeting faces hurdles
Ceramides may help Alzheimer's but brain barriers and safety remain unclear
This narrative review examines the role of ceramides in Alzheimer's disease, highlighting their involvement in neural and immune homeostasis…
A review suggests ceramides could support brain health in Alzheimer's, yet blood-brain barriers and safety concerns limit current use.
GLP-1 receptor agonists may reduce cognitive decline in type 2 diabetes patients with dementia
GLP-1 drugs may slow cognitive decline in type 2 diabetes
A systematic review of systematic reviews and meta-analyses found that GLP-1 receptor agonists are associated with reduced overall cognitive…
A review of reviews suggests GLP-1 drugs like Ozempic may help protect memory and thinking in people with type 2 diabetes.
Remote transitional care improves depressive symptoms in stroke patients, meta-analysis finds
Remote care helps stroke patients feel less depressed
A meta-analysis of 6 randomized controlled trials found that remote transitional care significantly improved depressive symptoms in stroke p…
A meta-analysis of six trials found remote transitional care significantly reduced depressive symptoms in stroke patients, though effects on…
Bipolar disorder is associated with a 3.65-fold higher risk of Parkinson's disease in six cohort studies
People with bipolar disorder face higher risk of developing Parkinson's disease based on recent analysis
This meta-analysis of six cohort studies evaluated the incidence of Parkinson's disease in individuals with bipolar disorder. The pooled ana…
A review of six studies found people with bipolar disorder have a much higher chance of getting Parkinson's disease. However, experts say we…
Delirium-directed interventions show mixed long-term cognitive outcomes in ICU survivors with acute respiratory failure
New review finds no lasting brain boost for ICU patients after delirium
This systematic review synthesizes four randomized clinical trials and one contextual trial regarding delirium-directed interventions in ICU…
A review of four trials found no lasting improvement in thinking skills or daily life for ICU patients treated for delirium.
Triple Pill Therapy Lowers Recurrent Stroke Incidence in Patients With Prior Intracerebral Hemorrhage
Single pill with three blood pressure drugs cuts stroke risk after brain bleed
This multinational randomized controlled trial enrolled 1670 patients with a history of intracerebral hemorrhage and baseline systolic blood…
A single pill combining three low-dose blood pressure drugs reduced recurrent stroke risk by 39% in people who had a brain bleed.
Meta-analysis identifies 311 serum metabolite associations in Alzheimer's disease trajectory
New blood tests reveal how Alzheimer's changes your body over seven years
This meta-analysis of 1,430 ADNI participants identified 311 significant serum metabolite associations across 15 Alzheimer's disease phenoty…
A seven-year study found that specific chemicals in your blood change over time as Alzheimer's disease progresses, offering new clues about …
HMC3 microglial model illuminates neurodegenerative mechanisms and early therapeutic discovery
New tool helps scientists study brain cell stress in Alzheimer's and Parkinson's disease
This narrative review synthesizes experimental evidence from HMC3 human microglial cell line and co-culture systems to explore mechanisms in…
Scientists use a special human brain cell line to study stress and cell death in diseases like Alzheimer's and Parkinson's, offering a new w…
TREM2 activation lowers amyloid plaques and tau in Alzheimer's disease animal models across twelve studies
Boosting TREM2 activity helps clear brain plaques and improves memory in mouse models of Alzheimer's disease
A systematic review and meta-analysis of twelve preclinical studies shows TREM2 overexpression or agonist antibodies significantly reduce am…
A review of twelve studies shows that increasing TREM2 activity reduces harmful brain proteins and fixes memory loss in mice. This suggests …
Acupuncture Boosts Cognition in Alzheimer's and Mild Cognitive Impairment
Meta-analysis shows acupuncture improves cognitive function in Alzheimer's and mild cognitive impairment
A meta-analysis of 3362 patients finds acupuncture, alone or with Western medicine, significantly improves cognitive function in Alzheimer's…
A large analysis of 3,362 patients suggests acupuncture may improve cognitive function in Alzheimer's disease and mild cognitive impairment,…
Adding quantitative FDG-PET interpretation improves specificity in Alzheimer's diagnosis
Adding numbers to brain scans helps doctors spot Alzheimer's disease more often and with greater accuracy than looking alone
This systematic review and meta-analysis of 10 studies found that combining quantitative with visual FDG-PET interpretation improves diagnos…
A review of ten studies found that using both visual checks and computer numbers improves how well doctors tell Alzheimer's apart from other…