Mitochondrial ribosomal proteins MRPL44, NAM9, and GEP3 are essential for neuronal homeostasis and survival
Mitochondrial proteins may play a role in brain cell health
This mini-review explores the role of mitochondrial ribosomal proteins in neurodegenerative diseases. The authors conclude that alterations …
Specific proteins within your cells help manage energy and stress, but changes to these proteins are linked to the progression of neurodegen…
Third-wave therapies significantly reduce post-stroke depression symptoms with sustained mid- to long-term effects
Third-wave therapies show promise for post-stroke depression symptoms
This systematic review and network meta-analysis of 3106 patients found that third-wave therapies significantly improved post-stroke depress…
New analysis suggests third-wave psychological therapies can significantly reduce depression symptoms in stroke survivors over the long term…
In-hospital delays before reperfusion correlate with worse outcomes in patients undergoing endovascular thrombectomy
Time matters for stroke patients receiving endovascular thrombectomy
This meta-analysis of 505 patients with large vessel occlusion strokes found that while onset-to-randomization time did not significantly im…
For patients with large vessel occlusion strokes, every minute counts during the hospital stay to ensure better recovery and independence.
Ischemic stroke patients exhibit distinct gut microbiota profiles and altered functional pathways
Gut Bacteria Show Distinct Patterns in Ischemic Stroke Patients
This systematic review of observational studies analyzed the gut microbiota in 1,957 participants with ischemic stroke. Findings indicate si…
Research shows that people who have had an ischemic stroke often have different gut bacteria and inflammatory markers than healthy individua…
Low ADAMTS13 activity linked to ischemic stroke in meta-analysis of 8,993 patients
Low blood protein linked to higher stroke risk
This meta-analysis of 8,993 patients found that lower ADAMTS13 activity is associated with ischemic stroke (SMD -1.12; 95%CI -1.20 to -1.03)…
People with ischemic stroke have lower levels of a key blood protein. Could this be a new risk marker?
Maladaptive responses to chronic hypoxia at high altitude increase ischemic stroke risk through thrombogenesis
Understanding how high altitude environments impact the risk of stroke
This narrative review examines the pathophysiology of ischemic stroke in high-altitude populations exposed to chronic hypoxia and hypobaria.…
Living at high altitudes changes how the body handles low oxygen, which can lead to serious blood flow issues and stroke risks.
Bibliometric analysis identifies growing research trends and key hubs for short-chain fatty acids in cognitive impairment
Mapping the Growing Research on Gut Health and Memory Loss Diseases
This systematic review provides a bibliometric analysis of 425 WoSCC and 514 Scopus records regarding short-chain fatty acids (SCFAs) and co…
Scientists are tracking how gut-related compounds might help brain health. This review maps out years of research into these important links…
Heterogeneous management of Radiologically isolated syndrome highlights significant gaps in standardized treatment algorithms
Survey Reveals Gaps in Managing Radiologically Isolated Syndrome
This cross-sector survey of 127 neurologists evaluates real-world management practices for Radiologically isolated syndrome (RIS). The study…
New survey data shows that doctors currently lack standardized tools and consistent methods for managing patients with Radiologically Isolat…
New consensus algorithm guides JAK inhibitor choice for alopecia areata
New treatment plan helps patients with hair loss condition
A guideline by expert dermatologists presents a consensus-based treatment algorithm for alopecia areata using SALT scores, quality-of-life i…
A new expert guide helps doctors choose the right medications for people and teens dealing with alopecia areata.
General anesthesia improves functional independence and reperfusion in patients undergoing endovascular thrombectomy for ischemic stroke
General Anesthesia May Improve Outcomes for Ischemic Stroke Patients
This meta-analysis of 1601 patients found that general anesthesia (GA) was associated with a higher odds ratio of 1.24 for functional indepe…
General anesthesia may improve functional independence and reperfusion success for patients undergoing surgery to treat an acute ischemic st…
Shared molecular pathways and hub genes link endocrine disorders with periodontitis progression
Shared Molecular Pathways Link Endocrine Disorders and Periodontitis
This narrative review synthesizes the molecular mechanisms underlying the crosstalk between endocrine disorders and periodntis. It identifie…
New research identifies shared biological pathways that link endocrine disorders with gum disease, potentially changing how doctors treat bo…
Eye disease prevalence in Sub-Saharan African prisons to be assessed in new meta-analysis protocol
Eye disease rates in Sub-Saharan African prisons remain unknown
This meta-analysis protocol aims to estimate the prevalence of eye diseases among prison inmates in Sub-Saharan Africa. No results are avail…
A new protocol aims to uncover how common eye diseases are among prisoners in Sub-Saharan Africa, but results are not yet available.