Advanced experimental models and computational tools provide dynamic frameworks for understanding oral disease progression
New Research Tools Help Map Complex Oral Diseases
This mini-review examines the integration of advanced experimental models, such as organ-on-chip systems and patient-derived organoids, with…
Advanced modeling and AI tools are helping researchers better understand the molecular causes behind conditions like gum disease and oral ca…
Traumatic BPPV triples recurrence risk versus idiopathic BPPV in meta-analysis of 4,074 patients
Traumatic vertigo cases show higher rates of recurring symptoms
A meta-analysis of 4,074 patients found that traumatic BPPV (t-BPPV) has significantly poorer outcomes than idiopathic BPPV (i-BPPV), with a…
People with vertigo caused by an injury may face a much higher risk of their symptoms returning compared to those with the condition on its …
FDA Approves Emgality (galcanezumab) for Preventive Treatment of Migraine and Episodic Cluster Headache
FDA approves new monthly shot Emgality to prevent migraines and treat cluster headaches.
The FDA approved Emgality (galcanezumab) for preventive treatment of migraine and treatment of episodic cluster headache in adults. In two 6…
The FDA approved Emgality (galcanezumab) to prevent migraines and treat episodic cluster headaches in adults. It is a monthly injection that…
FDA Approves Vyepti (eptinezumab-jjmr) for Preventive Treatment of Migraine in Adults
FDA approves new migraine prevention drug Vyepti given by IV every 3 months
FDA approved Vyepti (eptinezumab-jjmr) for preventive treatment of migraine in adults. It is a calcitonin gene-related peptide antagonist ad…
The FDA approved Vyepti (eptinezumab-jjmr) to prevent migraines in adults. It is given as an IV infusion every three months. This offers a n…
FDA Approves Epidiolex (cannabidiol) for Seizures Associated with LGS, DS, or TSC
FDA approves new cannabis-based drug for severe epilepsy in children.
FDA approved Epidiolex (cannabidiol) oral solution for seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclero…
The FDA approved Epidiolex, a purified cannabis-derived drug, for seizures in patients aged 1 year and older with Lennox-Gastaut syndrome, D…
FDA Approves Ajovy (fremanezumab) for Preventive Migraine Treatment in Adults and Pediatric Patients
FDA approves Ajovy to prevent migraines in adults and children.
The FDA approved Ajovy (fremanezumab) for preventive treatment of migraine in adults and episodic migraine in pediatric patients aged 6-17 y…
The FDA approved Ajovy (fremanezumab) to prevent migraines in adults and in children ages 6 to 17 who weigh at least 45 kg. It is a monthly …
MIND diet shows greater cognitive improvement in community-dwelling adults with high biomarker levels over three years
MIND diet linked to better brain health in older adults with high biomarkers
In a randomized clinical trial, the MIND diet demonstrated superior longitudinal cognitive outcomes compared to a control diet among older a…
Older adults on the MIND diet showed greater cognitive improvement than controls when they had higher levels of specific brain biomarkers.
Periodontal disease is associated with a 2.67 odds ratio for Alzheimer's disease
Gum disease linked to higher Alzheimer's risk in large analysis
This meta-analysis of 291,057 participants identified a significant association between periodontal disease and Alzheimer's disease (OR = 2.…
A large analysis of 291,057 people found that gum disease is linked to nearly 3 times higher odds of Alzheimer's disease, but more research …
Cardio-cerebral ion channel dysfunction links SUDEP and long QT syndrome in epilepsy patients
Review suggests SUDEP and LQTS share a specific ion channel problem
This narrative review explores overlapping molecular mechanisms between sudden unexpected death in epilepsy (SUDEP) and long QT syndrome (LQ…
This review finds that sudden death in epilepsy may link to long QT syndrome through shared heart-brain electrical issues.
Meta-analysis shows tirofiban improves functional independence but raises intracranial hemorrhage risk in acute ischemic stroke patients
Tirofiban improves stroke recovery but raises bleeding risk
A meta-analysis of 4,210 patients found tirofiban increased functional independence at 90 days compared to conventional management. However,…
A review of 4210 patients finds tirofiban boosts functional independence after stroke but increases bleeding risk.
Oral vitamin B12 reduces deficiency risk in children but shows little impact on growth or cognition
Oral Vitamin B12 Cuts Deficiency in Children Under 12
This systematic review analyzed 16 trials involving 4083 children less than 12 years of age. Oral vitamin B12 supplementation alone versus p…
A review of 16 trials shows oral vitamin B12 reduces deficiency in children but does not improve growth, cognition, or anemia.
Isolated hypoglossal nerve palsy from carotid dissection shows 65.6% favorable outcomes with medical management in 87 adult patients
Early imaging helps diagnose hypoglossal nerve palsy from carotid artery dissection
This systematic review analyzed 87 adult patients with hypoglossal nerve palsy attributable to extracranial internal carotid artery dissecti…
A review of 87 patients found that early vascular imaging can help diagnose nerve palsy caused by carotid artery dissection, even when brain…