MRgFUS thalamotomy lesion connectivity patterns linked to tremor control in Parkinson's disease
What makes a Parkinson's tremor treatment last? Brain connections may hold the answer.
A retrospective observational study of 20 patients with tremor-dominant Parkinson's disease found durable tremor control after unilateral MR…
Parkinson's tremor relief lasts longer when brain lesions connect to movement areas rather than coordination centers, according to a new ana…
Bilingualism associated with different gray matter patterns in Alzheimer's variants but comparable cognition
Study finds different brain volume patterns in bilingual versus monolingual Alzheimer's patients
An observational study of 224 participants with amnestic AD or logopenic variant PPA found bilinguals showed different gray matter volume pa…
Bilingual Alzheimer's patients show different brain volume patterns than monolinguals, yet both groups scored similarly on cognitive tests.
Active bilingualism associated with delayed symptom onset in Alzheimer's disease clinical stages
Can speaking two languages actively delay Alzheimer's symptoms?
A retrospective observational study of patients with amnestic MCI, amnestic dementia, and biomarker-confirmed AD found active bilingualism w…
Actively speaking two languages is linked to a delay of over two years in the first signs of memory problems for people with mild cognitive …
Historical population lead exposure shows strong association with Motor Neurone Disease mortality in Australia
Could past lead exposure from gasoline be linked to Motor Neurone Disease deaths?
An Australian ecological study found a strong non-linear association between historical cumulative population blood-lead levels and MND mort…
Old gasoline lead exposure may be linked to higher Motor Neurone Disease death rates in Australia, according to new analysis of national dat…
Case report tracks urinary ADEV GluN1 levels in anti-NMDAR encephalitis patient during treatment
Single case study tracks brain inflammation marker in urine during treatment
A case report of a single female patient with anti-NMDAR encephalitis analyzed urinary astrocyte-derived extracellular vesicles (ADEVs). Lon…
Urine tests tracked brain inflammation changes in a patient with anti-NMDAR encephalitis, showing protein levels dropped over treatment and …
Parkinson disease death rates increased in US adults 65+ from 1999 to 2017
Parkinson's disease death rates rose in older U.S. adults from 1999 to 2017
An observational analysis of US national vital statistics found age-adjusted Parkinson disease death rates increased from 41.7 to 65.3 per 1…
Parkinson's disease death rates for older U.S. adults rose from 41.7 to 65.3 per 100,000 people between 1999 and 2017.
Marked hyperglycemia linked to higher parenchymal hematoma risk with bridging therapy versus direct EVT in stroke
High blood sugar linked to bleeding risk after stroke clot removal procedure
A post hoc analysis of 627 patients from the DIRECT-MT trial found that in those with admission glucose >11.1 mmol/L, bridging therapy (alte…
Very high blood sugar levels may increase bleeding risk for stroke patients who receive clot-busting drugs before mechanical clot removal.
Traumatic brain injury-related deaths analyzed in US population over 18-year period
What did 18 years of traumatic brain injury death data in the U.S. reveal?
An observational study analyzed traumatic brain injury-related death data in the United States population over an 18-year period (2000-2017)…
CDC data from 2000 to 2017 shows traumatic brain injury deaths remain a major public health concern across the entire United States.
Online behavioral intervention increases physical activity and improves depression in newly diagnosed multiple sclerosis
Can online coaching help people newly diagnosed with MS get moving and feel better?
A pilot randomized controlled trial in 50 people newly diagnosed with MS found that a 16-week COM-B-based online behavioral intervention sig…
Online coaching helped newly diagnosed MS patients add 11 minutes of daily activity, feel less depressed, and improve mental health quality …
Post hoc analysis finds cilostazol reduces stroke recurrence without lowering systolic blood pressure
Study finds cilostazol reduces stroke recurrence without lowering blood pressure
A post hoc mediation analysis of an RCT in 1,795 patients with noncardioembolic ischemic stroke found dual therapy with cilostazol plus aspi…
Cilostazol lowers stroke recurrence risk in patients with prior noncardioembolic strokes without working by dropping their blood pressure.
FDA Approves Kesimpta (ofatumumab) for Relapsing Forms of Multiple Sclerosis in Adults
The FDA approved a new monthly self-injection drug for multiple sclerosis.
The FDA has approved Kesimpta, a CD20-directed cytolytic antibody, for the treatment of relapsing forms of multiple sclerosis in adults. The…
The FDA approved Kesimpta, a new monthly self-injection for adults with relapsing forms of multiple sclerosis.
Brain Injury Awareness Month highlights needs of persons with TBI and families
What does Brain Injury Awareness Month mean for families living with TBI?
This non-research publication marks Brain Injury Awareness Month, focusing on persons living with traumatic brain injury and their families.…
March's Brain Injury Awareness Month shines a light on the long-term challenges families face after a head injury, bringing these experience…