ANCA-associated vasculitis associated with higher mortality and cardiovascular events in retrospective cohort analysis
New data links rare blood vessel diseases to higher death and heart risks
This retrospective cohort study analyzed 20,422 patients with granulomatosis with polyangiitis and 5,907 with microscopic polyangiitis using…
People with rare blood vessel diseases face nearly three times the death risk and higher heart attack rates compared to healthy people.
Retrospective cohort identifies risk factors and predicts postherpetic neuralgia risk in patients with herpes zoster
New model predicts nerve pain risk following shingles outbreaks in patients
This retrospective cohort study evaluated 846 patients with herpes zoster to predict postherpetic neuralgia risk.
A new computer model predicts who will develop long-term nerve pain after shingles by spotting key risks like older age, diabetes, and sever…
Baseline and 6-month tinnitus burden negatively associated with 2-year quality of life in single-sided deafness after cochlear implantation
Silence isn't the only goal after implant surgery
This secondary complete-case analysis of a prospective longitudinal cohort included 36 adults with postlingual single-sided deafness who und…
For adults with single-sided deafness, cochlear implants improve hearing but often leave tinnitus and stress unchanged, affecting quality of…
Systemic corticosteroids associated with greater hearing gain than intratympanic therapy in idiopathic SSNHL
Systemic steroids beat ear drops for sudden hearing loss
This single-center retrospective cohort study evaluated 284 adults with idiopathic sudden sensorineural hearing loss comparing initial syste…
Taking steroids by mouth or IV works better than putting them in the ear for sudden hearing loss.
Neurosurgery patients with brain tumors show preoperative financial capacity deficits compared to healthy controls
Brain tumor surgery patients often struggle with financial tasks before and after the operation
This prospective observational study evaluated 21 patients with brain tumors and 21 age- and education-matched healthy controls.
Brain tumor surgery patients often struggle with financial tasks like reading bills, and many overestimate their ability to manage money.
Phase I trial assesses intravenous urokinase dosing in acute ischemic stroke patients
New Stroke Drug Dose Could Save More Brains
This prospective, single-center, phase I, dose-escalation clinical trial protocol evaluated intravenous urokinase at 15,000, 20,000, 25,000,…
Doctors may soon give stroke patients a weight-based dose of urokinase to clear clots faster and reduce risky guessing.
CTA-derived radiomics features associated with prediction of ipsilateral stroke recurrence in retrospective carotid atherosclerosis cohort
New scan analysis might predict stroke risk better than usual checks
This retrospective cohort study included 162 patients with unilateral carotid atherosclerosis and a mean age of 69.28 ± 8.30 years.
A new scan analysis predicts stroke risk better than usual checks by measuring texture in neck artery plaque and surrounding fat.
Retrospective cohort associates higher NHR with poor functional outcome after acute ischemic stroke reperfusion
Could a simple blood ratio predict poor recovery after stroke treatment?
This retrospective cohort study of 367 acute ischemic stroke patients with successful reperfusion found higher neutrophil-to–high-density li…
A simple blood ratio of immune cells to good cholesterol may help predict poor recovery three months after stroke treatment.
Otoconial repositioning alters brain connectivity in benign paroxysmal positional vertigo patients
Does fixing your inner ear also fix how your brain connects?
This cohort study enrolled 29 patients with benign paroxysmal positional vertigo (BPPV) and 29 healthy controls.
Treating inner ear dizziness strengthens brain connections in visual and sensory areas, but full recovery takes longer than a week.
Transnasal transsphenoidal resection outcomes in 212 patients with non-functioning pituitary macroadenomas show variable progression rates
Research examines pituitary tumor recurrence and stability after surgical removal
This retrospective cohort study evaluated 212 patients with histologically confirmed non-functioning pituitary macroadenomas undergoing tran…
Larger pituitary tumors before surgery make it more likely for remaining tissue to grow back after removal, according to a study of 212 pati…
Blood miR-7-5p levels decrease more rapidly in Parkinson's disease patients than in healthy controls
Blood Test Tracks Parkinson's Progress
This observational cohort study in the PPMI cohort found that blood miR-7-5p levels decreased more rapidly in people with Parkinson's diseas…
A new blood test tracks Parkinson's disease progress by measuring a molecule that drops faster in patients than healthy people.
Real-world cohort examines Alemtuzumab effects on bowel/bladder function and latent progressive trajectories in MS patients
Did you know MS patients hide worsening symptoms that doctors might miss for years?
This real-world cohort study involving 1,025 MS patients utilized a trajectory-based statistical approach to analyze disease progression.
Doctors might miss worsening MS symptoms for years because patients hide them, but a new method found over 11,000 hidden patterns in real-wo…