Meta-analysis identifies 311 serum metabolite associations in Alzheimer's disease trajectory
New blood tests reveal how Alzheimer's changes your body over seven years
This meta-analysis of 1,430 ADNI participants identified 311 significant serum metabolite associations across 15 Alzheimer's disease phenoty…
A seven-year study found that specific chemicals in your blood change over time as Alzheimer's disease progresses, offering new clues about …
HMC3 microglial model illuminates neurodegenerative mechanisms and early therapeutic discovery
New tool helps scientists study brain cell stress in Alzheimer's and Parkinson's disease
This narrative review synthesizes experimental evidence from HMC3 human microglial cell line and co-culture systems to explore mechanisms in…
Scientists use a special human brain cell line to study stress and cell death in diseases like Alzheimer's and Parkinson's, offering a new w…
TREM2 activation lowers amyloid plaques and tau in Alzheimer's disease animal models across twelve studies
Boosting TREM2 activity helps clear brain plaques and improves memory in mouse models of Alzheimer's disease
A systematic review and meta-analysis of twelve preclinical studies shows TREM2 overexpression or agonist antibodies significantly reduce am…
A review of twelve studies shows that increasing TREM2 activity reduces harmful brain proteins and fixes memory loss in mice. This suggests …
Acupuncture Boosts Cognition in Alzheimer's and Mild Cognitive Impairment
Meta-analysis shows acupuncture improves cognitive function in Alzheimer's and mild cognitive impairment
A meta-analysis of 3362 patients finds acupuncture, alone or with Western medicine, significantly improves cognitive function in Alzheimer's…
A large analysis of 3,362 patients suggests acupuncture may improve cognitive function in Alzheimer's disease and mild cognitive impairment,…
Adding quantitative FDG-PET interpretation improves specificity in Alzheimer's diagnosis
Adding numbers to brain scans helps doctors spot Alzheimer's disease more often and with greater accuracy than looking alone
This systematic review and meta-analysis of 10 studies found that combining quantitative with visual FDG-PET interpretation improves diagnos…
A review of ten studies found that using both visual checks and computer numbers improves how well doctors tell Alzheimer's apart from other…
Six novel loci and nine recessive loci identified for young onset Parkinson's disease in European ancestry
Genetic clues to young onset Parkinson's disease found in large global study
This meta-analysis of genome-wide association studies in 1,528 patients and 20,408 controls identified six independent loci and nine recessi…
A massive analysis of genetic data found six new spots in our DNA linked to early Parkinson's disease, offering hope for better prevention a…
IBD-related neuroimaging shows brain alterations in emotional networks with distinguishable phenotypes for Crohn's and ulcerative colitis
Brain scans show different emotional patterns in Crohn's and ulcerative colitis
This bibliometric analysis and systematic scoping review examines 175 articles on IBD-related neuroimaging literature from Web of Science an…
A review of 175 articles found that brain activity in Crohn's and ulcerative colitis affects emotion centers differently. This suggests dist…
Thrombectomy plus intra-arterial alteplase increases excellent functional outcome to 57.5% at 90 days
Adding Alteplase to Thrombectomy Improves Stroke Recovery in This Trial
This randomized, open-label trial with blinded outcome assessment in 440 patients with acute ischemic stroke found that adding intra-arteria…
A Spanish trial found adding intra-arterial alteplase to thrombectomy increased excellent recovery rates without significantly raising bleed…
Ethanol exposure and high-fat diet may impair amyloid-beta clearance and promote oxidative stress in Alzheimer's disease
Ethanol and high-fat diets may worsen Alzheimer's disease markers
This narrative review examines the potential impact of ethanol exposure and high-fat diet on Alzheimer's disease pathology. The authors sugg…
A review suggests alcohol and poor diet together might increase Alzheimer's risk by damaging brain cells and boosting inflammation.
Non-invasive brain stimulation with motor imagery improves upper limb function after stroke with WMD 5.75
Non-invasive brain stimulation helps stroke patients move their arms better
This systematic review and meta-analysis of 21 studies found that non-invasive brain stimulation combined with motor imagery significantly i…
Combining brain stimulation with motor imagery significantly improves arm movement and daily tasks for stroke survivors in this analysis of …
FDA Approves Morphine Sulfate Injection for Severe Pain Requiring Opioid Analgesic
FDA approves morphine injection for severe pain when other treatments fail.
FDA approved Morphine Sulfate Injection for management of pain severe enough to require an opioid analgesic and for which alternative treatm…
The FDA approved Morphine Sulfate Injection, an opioid, for severe pain that requires an opioid and when other treatments are not enough. Th…
FDA Approves Soliris (eculizumab) for Generalized Myasthenia Gravis and NMOSD
FDA approves Soliris for two rare autoimmune diseases.
The FDA approved Soliris (eculizumab) for generalized myasthenia gravis (gMG) in anti-AChR antibody-positive patients aged 6 years and older…
The FDA approved Soliris for generalized myasthenia gravis and neuromyelitis optica spectrum disorder. These are rare conditions where the i…