Technical evaluation of sEEGnal automated EEG preprocessing pipeline versus expert-driven manual methods
New Software Matches Expert Quality for Brain Wave Analysis
This methodological development evaluates the sEEGnal automated EEG preprocessing pipeline against expert-driven manual preprocessing.
New automated software cleans messy brain wave data as accurately as human experts, helping doctors trust their diagnostic results faster.
Meta-analysis models cost-effectiveness of IV alteplase plus thrombectomy for large vessel occlusion stroke
Adding alteplase to stroke surgery is cost-effective when treatment starts within 170 minutes
This meta-analysis models cost-effectiveness using individual patient data from 6 trials involving 2,268 patients across 16 countries.
Adding clot-busting medicine to stroke surgery saves money and improves value when treatment starts within 170 minutes, but benefits fade af…
Upadacitinib shows 94.1% remission at 26 weeks in Crohn's disease cohort
Study compares upadacitinib and other therapies for Crohn's disease remission
This retrospective cohort study of 218 individuals with Crohn's disease found a 94.1% clinical remission rate at 26 weeks for upadacitinib, …
Upadacitinib showed a 94.1% remission rate for Crohn's disease patients at 26 weeks, but this finding comes from a very small group of just …
Obesity associated with reduced SLE relapse rates in Japanese registry cohort
A Surprising Link Between Weight and Lupus Flares
This observational cohort study of 1134 patients with systemic lupus erythematosus in Japan found that obesity (BMI ≥25 kg/m2) was associate…
Being overweight or mildly obese might lower the risk of lupus relapses, challenging common beliefs about weight and autoimmune disease.
Meta-analysis links chronic kidney disease to higher mortality after intracerebral hemorrhage
Kidney Disease Linked to Higher Stroke Death Risk
This meta-analysis of 5,000 patients with spontaneous intracerebral hemorrhage found that chronic kidney disease was associated with higher …
Kidney disease makes surviving a brain bleed much harder, raising the risk of death and disability for patients with this common condition.
Masitinib 4.5 mg/kg/day associated with survival in ALS post-hoc analysis
This Drug Could Add Nearly Two Years to ALS Life
This post-hoc analysis of a randomized, double-blind, placebo-controlled trial in 130 ALS patients found that masitinib 4.5 mg/kg/day was as…
A new look at data suggests a specific drug might significantly extend life for some people with ALS.
Intermittent theta-burst stimulation of right putamen improves motor scores in Parkinson's disease patients
New Non-Invasive Method Eases Parkinsons Motor Symptoms Without Surgery
This randomized controlled trial in 19 Parkinson's disease patients found that intermittent theta-burst transcranial temporal interference s…
A new non-surgical brain treatment showed promise in reducing movement problems for Parkinsons patients.
Meta-analysis links speech features to severity in Parkinsons, cerebral palsy, and ALS
Speech patterns may help track disease severity in Parkinsons and other conditions
This meta-analysis synthesizes evidence from 890 speakers across 5 languages to evaluate a training-free method for assessing speech degrada…
A new computer method tracks Parkinson's and other disease severity by measuring how specific speech sounds change without needing special t…
Telemedicine network associated with lower 90-day mortality and care needs in rural acute neurological disorders
Could a 24/7 telemedicine network help rural hospitals save lives after a stroke or brain injury?
This prospective cohort study in rural northeast Germany evaluated a digitally enabled hub-and-spoke telemedicine network for adults with ac…
Rural hospitals using a 24/7 telemedicine network saw lower death or nursing home rates for stroke patients compared to similar facilities w…
Neutrophil SIRL-1/IL-8 Ratio as a Diagnostic Biomarker for Inflammatory Bowel Disease
New Blood Ratio Could Spot IBD Faster
This single-center cohort study measured neutrophil SIRL-1 and serum IL-8 in 90 IBD patients and healthy volunteers.
A new blood ratio measuring two immune signals could help doctors diagnose Crohn's and Ulcerative Colitis faster and more accurately.
SHAP-based model predicts pneumonia after aneurysmal subarachnoid hemorrhage embolization
Doctors Can Now Predict a Dangerous Complication After Brain Bleeds
This retrospective cohort study of 290 patients with aneurysmal subarachnoid hemorrhage evaluated a prediction model for stroke-associated p…
Doctors can now predict who will develop pneumonia after a brain bleed, allowing faster action to save lives.
Gut microbiota and inflammatory biomarkers associate with 1-year neurological recovery in cerebral hypoxia-ischemia cohort
Gut Bacteria Could Predict Brain Recovery After Oxygen Loss
This single-center cohort study analyzed 772 patients with cerebral hypoxia-ischemia to identify biomarkers associated with 1-year neurologi…
Gut bacteria levels and blood markers can predict how well a patient will recover after a stroke or cardiac arrest.