Meta-analysis links mitochondrial polygenic score to alpha-synuclein seeding in LRRK2-related Parkinson's disease
A new test detects Parkinson's linked to a specific gene variant in most cases
This meta-analysis evaluates the association between CSF-based alpha-synuclein seed amplification assay (aSyn SAA) and LRRK2-related Parkins…
A new blood test found alpha-synuclein in 80 percent of people with Parkinson's linked to a specific gene variant, helping distinguish this …
Review of ivermectin MDA for onchocerciasis and hookworm co-infections in endemic regions
Ivermectin helps clear hookworm even when people also carry river blindness
This narrative review synthesizes evidence on preventative chemotherapy and Mass Drug Administration with ivermectin for onchocerciasis and …
A review shows ivermectin treatment improves outcomes for people infected with both river blindness and hookworm, though more data on immune…
Comprehensive review examines nano-adjuvant technologies for poultry vaccines globally
Nano-adjuvants may boost poultry vaccines and protect birds from new viruses
This comprehensive review evaluates nano-adjuvant technologies, including lipid nanoparticles and polymeric systems, compared to existing li…
A global review suggests nano-adjuvant technologies could make poultry vaccines safer, more effective, and easier to use against emerging vi…
Glomerular Hyperfiltration Linked to Higher Mortality in Stroke and TIA Patients
Stroke Survivors Overlooked Danger Doubles Death Risk
An individual patient data meta-analysis of 11,175 patients with stroke or TIA found that glomerular hyperfiltration (eGFR > age- and sex-ad…
• Kidney overwork sharply raises death risk after stroke • Helps stroke patients and their doctors monitor better • Not yet routine care nee…
Early dual antiplatelet therapy improves outcomes after ischaemic stroke thrombolysis
Stroke Patients Gain Better Recovery With Early Double Blood Thinner Combo
A Chinese trial found that starting aspirin and ticagrelor within six hours after thrombolysis boosted excellent functional outcomes at 90 d…
Adding a second blood thinner within hours helps more stroke patients regain full function without raising bleeding risks
Tenecteplase linked to higher thrombus migration than alteplase in acute ischemic stroke with EVT
Tenecteplase linked to more clot movement than alteplase in stroke patients
This secondary analysis of a randomized controlled trial in 496 patients with intracranial occlusion found that IV tenecteplase was associat…
A study found tenecteplase caused more clot movement than alteplase in stroke patients. This movement was tied to better recovery odds.
AI-assisted PET radiomics improves Alzheimer's diagnosis over conventional methods in meta-analysis
AI helps PET scans spot early Alzheimer’s with new precision
A systematic review of 5,765 patients shows AI radiomics significantly boosts diagnostic accuracy for Alzheimer's versus mild cognitive impa…
AI-powered PET scans may better distinguish early Alzheimer’s from mild memory loss, but results for healthy people are less clear.
Narrative review refutes causal link between endometriosis and migraine
Endometriosis and Migraine Share Hidden Genetic Roots
This narrative review examines the association between endometriosis and migraine. The authors refute a causal relationship and discuss shar…
New genetic research suggests endometriosis and migraine are parallel conditions driven by shared inflammatory pathways, not just hormones.
Exosome therapy reduces seizures and inflammation in preclinical epilepsy models: a meta-analysis
Tiny Particles From Stem Cells Could Quiet Epilepsy Seizures
This systematic review and meta-analysis of 8 preclinical studies found that exosome therapy reduced seizure duration, frequency, and latenc…
What if a simple infusion of microscopic particles could calm the brain storms of epilepsy without the side effects of today's drugs.
Systematic review and meta-analysis of intra-arterial tenecteplase after endovascular thrombectomy for acute ischemic stroke
A Stroke Drug Given After Clot Removal Boosts Recovery
This systematic review and meta-analysis evaluated intra-arterial tenecteplase (IA-TNK) versus endovascular thrombectomy (EVT) alone in pati…
A clot-busting drug given right after a stroke procedure helped more patients walk and live independently, with no extra bleeding risk.
Narrative review discusses neurodegenerative diseases without reporting specific interventions or outcomes
New hope for brain health by fixing the cells that clean up waste
This source is a narrative review focusing on neurodegenerative diseases. The authors did not report specific interventions, populations, sa…
A new review explains how fixing the cell cleaning system could help stop brain diseases from getting worse
Narrative review examines RNA editing alterations in Parkinson's disease patients
Parkinson’s RNA editing changes may guide future treatments
This narrative review discusses RNA editing patterns in Parkinson's disease. Evidence suggests these patterns undergo significant alteration…
Parkinson’s patients show clear changes in RNA editing, which may reveal new treatment paths.