Cross-sectional CSF proteomic analysis identifies ALS-specific biomarker signature
ALS Blood Test Breakthrough Could Speed Diagnosis
This observational cross-sectional study analyzed CSF proteomics in 237 participants to identify ALS-specific biomarkers.
A new five-protein blood test pattern could finally help doctors spot ALS early, before nerve damage becomes too advanced.
Narrative review explores fMRI utility in otolaryngology disorders including tinnitus and vestibular migraine
The Brain Scan Changing How Doctors See Hearing and Balance Problems
This narrative review examines the application of functional magnetic resonance imaging (fMRI) in patients with otolaryngology–head and neck…
A new brain scan shows that tinnitus and hearing loss aren't just ear problems, but actually change how the brain works.
Review of liver disease immunomodulation strategies notes precision over broad suppression
Your Liver's Immune Cells Play Both Hero and Villain at Once
This narrative review examines immunomodulation approaches for liver diseases, including acute liver injury, HBV infection, MASLD/MASH, fibr…
Liver immune cells can both damage and repair your organ at the same time, a discovery that could unlock new precision treatments for hepati…
Serum PAI-1, MMP-9, and NLR are higher in elderly acute ischemic stroke patients
Three Blood Markers Together Predict Stroke Recovery Better Than One Score Alone
In this prospective observational cohort study of 113 elderly acute ischemic stroke patients and 63 elderly controls, serum levels of PAI-1,…
Adding three blood proteins to a standard stroke score better predicts recovery at 90 days for older adults who have just had a clot-based s…
Robot-assisted stereotactic brain biopsy showed shorter operative time versus frame-based biopsy in 54 patients
Robotic Brain Biopsies Are Faster and Just as Safe as the Old Method
This retrospective cohort study evaluated 54 patients undergoing stereotactic brain biopsy at Jiangxi Provincial People's Hospital.
A new robotic system for brain biopsies cuts operating time significantly while matching the safety and precision of the traditional frame-b…
Abdominal acupuncture added to tDCS improves post-stroke depression in randomized trial
Abdominal acupuncture plus tDCS showed better results than tDCS alone for post-stroke depression in a small trial
In a randomized trial of 126 patients with post-stroke depression (90 analyzed after 1:1 propensity score matching), abdominal acupuncture a…
Adding abdominal acupuncture to standard tDCS therapy improved depression, daily function, and sleep quality in stroke patients more than tD…
Auricular electroacupuncture raises tracheotomy extubation success after stroke versus swallowing electrical stimulation
Can a specific needle treatment help stroke patients breathe without a breathing tube sooner?
This randomized trial of 84 post-stroke tracheotomy patients compared auricular electroacupuncture plus routine care against swallowing elec…
Adding ear and throat needles to standard care helped stroke patients remove breathing tubes faster, cough stronger, and swallow safer than …
Acupuncture frequency affects aphasia outcomes post-stroke in randomized trial
Does acupuncture speed up speech recovery after stroke, and does the needle speed matter?
This randomized controlled trial in 105 patients with post-ischemic stroke aphasia compared low-frequency and high-frequency acupuncture at …
Slowly twirling acupuncture needles helped stroke patients recover speech and understanding better than fast needles or fake needles after s…
Protocol for cane training trial in Parkinson's disease to assess gait speed and confidence
Could simple cane training help people with Parkinson's walk faster and feel safer?
This is a protocol for a randomized controlled trial in 26 individuals with Parkinson's disease.
A new trial tests whether four cane training sessions can help people with Parkinson's walk faster and feel safer, addressing freezing of ga…
Oral cladribine reshapes CSF immune cell composition in relapsing multiple sclerosis
Cladribine therapy changes immune cells in fluid from the brain in a small MS study
This single-site phase IV clinical trial used single-cell sequencing on CSF and blood from 13 individuals with relapsing MS before and after…
Cladribine therapy reshapes immune cells in the brain's fluid by reducing harmful memory B cells while boosting protective Treg cells in mul…
Protocol for pilot RCT of neuromodulation-augmented balance training in ambulatory people with multiple sclerosis
New Balance Trick Helps MS Walkers Move Better
This published protocol describes a pilot randomized trial evaluating the feasibility, acceptability, safety, and preliminary clinical effic…
This new approach combines simple exercises with gentle electrical signals to help people with multiple sclerosis walk more confidently.
Elevated monocyte-to-HDL ratio associated with stroke predisposition in U.S. adults
High monocyte-to-HDL cholesterol ratio linked to higher stroke risk in adults
This cross-sectional study of 43,321 U.S.
High monocyte-to-HDL cholesterol ratios are linked to a higher risk of stroke in U.S. adults, based on data from over 43,000 people.