Multicomponent nonpharmacological interventions reduce delirium incidence in adult patients with cancer
Non-drug approaches cut delirium risk in cancer patients
This meta-analysis evaluated various nonpharmacological interventions to determine their impact on delirium incidence in adult cancer patien…
A review of 2,747 patients finds that multicomponent non-drug interventions can reduce delirium in cancer patients, especially after surgery…
Neurotoxic chemotherapy causes moderate to large increases in vibration perception threshold in hands and feet
Chemotherapy Linked to Loss of Sensation in Hands and Feet
This meta-analysis of 1635 patients receiving neurotoxic chemotherapy found significant increases in vibration perception threshold (VPT) in…
New analysis shows that certain chemotherapy drugs can cause a significant loss of sensation in the hands and feet for many patients.
miRNA panels show high diagnostic accuracy for endometrial cancer in meta-analysis
miRNA Panels Show High Accuracy for Endometrial Cancer Diagnosis
This meta-analysis of 531 participants found that miRNA panels have high diagnostic accuracy for endometrial cancer, with pooled sensitivity…
A new analysis finds miRNA panels may accurately detect endometrial cancer, but more research is needed before routine use.
Multidimensional models incorporating genomic and microenvironment features likely outperform single-analyte tests to predict immunotherapy response
Multi-Omic Biomarkers May Improve Lung Cancer Treatment Predictions
This narrative review explores the integration of chemokine signatures and multi-omic biomarkers to predict immune checkpoint inhibitor resp…
New research suggests that combining multiple biological markers can better predict how lung cancer patients will respond to immunotherapy.
Radiomics-based artificial intelligence models predict VETC presence in patients with hepatocellular carcinoma
AI helps predict aggressive liver cancer growth patterns
Researchers evaluated the diagnostic accuracy of radiomics-based AI models using various imaging modalities to identify vessel-encapsulated …
New AI tools can identify specific high-risk markers in liver cancer scans, helping doctors better predict which tumors are likely to return…
Liquid biopsy technologies utilizing NGS and machine learning improve analytical sensitivity for early cancer detection
Liquid Biopsies Show Promise for Early Multi-Cancer Detection
This mini-review synthesizes current literature on liquid biopsy modalities including ctDNA, exosomes, and epigenetic fingerprints for multi…
New liquid biopsy technologies use machine learning and advanced testing to detect multiple types of cancer early through a simple blood sam…
Acupuncture promotes microglial transition from pro-inflammatory glycolysis to anti-inflammatory oxidative phosphorylation metabolism
Acupuncture May Tame Brain Inflammation by Changing Energy Use
This systematic review explores the mechanisms of acupuncture in neuroinflammation, specifically focusing on microglial glucose metabolism r…
Acupuncture may calm brain inflammation by shifting immune cells from a pro-inflammatory to an anti-inflammatory state.
Serum 25-hydroxyvitamin D shows significant inverse correlation with insulin resistance indices in women with PCOS
Vitamin D Levels Linked to Insulin Resistance in PCOS
This meta-analysis of 1856 women with Polycystic Ovary Syndrome found a significant inverse correlation between serum 25(OH)D and insulin re…
Lower vitamin D levels are linked to higher insulin resistance in women with Polycystic Ovary Syndrome, especially in specific groups.
IL-10 rs1800890 variants linked to modestly increased non-Hodgkin lymphoma risk in meta-analysis
Gene Variants Linked to Higher Non-Hodgkin Lymphoma Risk
This meta-analysis of 53,864 cases and 60,448 controls found that certain IL-10 polymorphisms (rs1800890 and rs1800896) are associated with …
Certain IL-10 gene variants may slightly raise the risk of non-Hodgkin lymphoma, a large analysis finds.
CAR-T cell therapy improves progression-free survival (HR 0.55) and overall survival (HR 0.68) in R/R DLBCL
CAR-T cell therapy shows improved survival for certain blood cancers
This meta-analysis of 2150 adult patients with relapsed or refractory diffuse large B-cell lymphoma found that CAR-T cell therapy significan…
New analysis shows CAR-T cell therapy significantly improves survival and response rates for patients with relapsed or refractory DLBCL.
ALK tyrosine kinase inhibitors achieve 58.5% objective response rate in ALK-positive non-small cell lung cancer
New data shows how ALK inhibitors treat lung cancer
This meta-analysis of 6382 adults with ALK-positive non-small cell lung cancer (NSCLC) found an overall objective response rate (ORR) of 58.…
Recent analysis shows that newer generations of targeted drugs offer significant response rates for patients with specific types of lung can…
Robot-assisted radical nephrectomy reduces conversion rates and blood loss compared to laparoscopic surgery for complex tumors
Robot-assisted Surgery Shows Benefits for Complex Renal Tumors
This meta-analysis of 4,163 patients evaluated robot-assisted radical nephrectomy (RARN) versus laparoscopic radical nephrectomy (LRN) for h…
Robotic surgery may reduce blood loss and the need for transfusions while preserving kidney function in patients with complex renal tumors.