Non-vaccine immunotherapies show no survival advantage over vaccines in pediatric malignant brain tumors
Immune therapies for childhood brain tumors show similar survival rates
This exploratory meta-analysis of 20 studies compared various immunotherapy modalities for pediatric malignant brain tumors. The analysis fo…
New data shows that while several types of immunotherapy offer similar survival rates for children with brain tumors, some carry much higher…
Innovative biomarkers and point-of-care tools offer non-invasive alternatives to traditional orthodontic treatment monitoring
New Tools Offer Non-Invasive Ways to Monitor Orthodontic Treatment
This narrative review examines the transition from traditional orthodontic monitoring methods to innovative diagnostic tools. The authors sy…
Newer diagnostic tools like saliva biomarkers and AI software may offer safer, faster ways to monitor orthodontic progress compared to tradi…
Breast cancer mortality in older US adults declines but slowdown after 2014 and disparities persist
Breast Cancer Deaths Fall, But Gains Slow After 2014
This population-based repeated cross-sectional mortality analysis examined breast cancer mortality among US adults aged 65 and older, using …
U.S. breast cancer death rates dropped from 1999 to 2020, but the decline slowed after 2014, and gaps by age, race, and place remain.
High CALLY index correlates with improved survival in hepatobiliary and pancreatic malignancies
High CALLY index linked to better survival in liver and pancreatic cancers
This meta-analysis of 3833 patients found that a high C-reactive protein-albumin-lymphocyte (CALLY) index is associated with significantly b…
A high CALLY score may signal better survival outcomes for patients with liver, bile duct, and pancreatic cancers.
Immune dysfunction involving multiple cell types creates an immunosuppressive microenvironment in clear cell renal cell carcinoma
Immune Checkpoint Inhibitors and Immune Dysfunction in Kidney Cancer
This narrative review examines the role of immune dysfunction in clear cell renal cell carcinoma (ccRCC). It identifies how various immune c…
New research highlights how specific immune cells create a protective shield for kidney cancer, potentially making it harder for treatments …
Immune Checkpoint Inhibitors Combined With Chemotherapy Improve Pathological Complete Response in TNBC
Immunotherapy Combined With Chemotherapy Shows Higher Response Rates in TNBC
Combining immune checkpoint inhibitors with chemotherapy significantly improves pathological complete response rates in patients with triple…
Adding immunotherapy to chemotherapy may improve response rates for patients with early-stage or high-risk triple-negative breast cancer.
Piperacillin treatment resolves symptoms and normalizes inflammatory markers in a case of prostatic malakoplakia
Piperacillin Treatment Shows Promise for Prostate Malakoplakia Cases
This case report and narrative literature review describes a 64-year-old male with prostatic malakoplakia who experienced complete symptom r…
A rare condition called prostatic malakoplakia can mimic prostate cancer on scans, but a new case report shows how antibiotics may resolve s…
Multimodal treatment and surgical resection manage ameloblastic carcinoma with no recurrence at 6 months
Treatment Approach for a Rare Case of Ameloblastic Carcinoma
This case report and literature review describes a 17-year-old male with maxillary ameloblastic carcinoma treated with surgery, radiotherapy…
A new case report details the surgical and radiation treatment of a rare jaw cancer in a teenager, highlighting the importance of thorough i…
Contrast-enhanced ultrasound shows 0.95 accuracy in distinguishing malignant from benign renal masses
Ultrasound imaging helps doctors tell kidney cancer from benign masses
This meta-analysis of 4,530 renal masses evaluated the diagnostic accuracy of contrast-enhanced ultrasound (CEUS). The analysis found a sens…
A new look at ultrasound imaging shows it can accurately distinguish between cancerous and non-cancerous kidney masses.
GCC Consensus Defines 75% Agreement Threshold for Advanced Endometrial Cancer Care
Experts Set Regional Guidance For Advanced Endometrial Cancer
This guideline reports a modified-Delphi consensus process involving 12 experts to identify unmet needs and develop regionally adapted recom…
Twelve experts in the Gulf region agreed on how to better diagnose and manage advanced endometrial cancer.
FDA Approves Nubeqa (darolutamide) for Non-Metastatic Castration-Resistant and Metastatic Castration-Sensitive Prostate Cancer
FDA Approves Nubeqa for Two Types of Advanced Prostate Cancer
The FDA has approved Nubeqa (darolutamide), an androgen receptor inhibitor, for adults with non-metastatic castration-resistant prostate can…
The FDA approved Nubeqa (darolutamide) for two forms of advanced prostate cancer: one that has not spread and one that has spread but still …
Immune cells and bone lineage cells interact via cytokines to modulate bone homeostasis in musculoskeletal disorders
Immune cells and bone cells work together in joint diseases
This systematic review synthesizes the bidirectional interactions between immune cells and bone lineage cells in conditions like rheumatoid …
New research reveals how immune cells and bone cells communicate to affect bone health in conditions like rheumatoid arthritis and osteoporo…