Meta-analysis finds modest melanoma risk increase among infertile women using fertility treatments
Fertility Drugs Linked to Slight Rise in Melanoma Risk
This systematic review and meta-analysis evaluated melanoma incidence in infertile women exposed to fertility treatments compared to untreat…
A large review finds fertility drugs may raise melanoma risk slightly, but the increase is small and more research is needed.
Laparoscopic transabdominal excision of presacral cyst shows no recurrence at 3 months in case report
Laparoscopic Surgery for Presacral Cysts Shows Early Promise in One Case
A case report and narrative mini-review describes a 39-year-old woman with a presacral cyst who underwent laparoscopic transabdominal radica…
A single patient with a presacral cyst recovered well after laparoscopic surgery with no complications or recurrence at three months.
TEAS significantly reduces overall PONV risk in patients undergoing breast surgery compared to sham stimulation or routine care
TEAS reduces nausea and pain for patients having breast surgery
This systematic review and meta-analysis evaluated transcutaneous electrical acupoint stimulation (TEAS) for postoperative nausea and vomiti…
A large review found that transcutaneous electrical acupoint stimulation significantly lowers the risk of nausea and vomiting after breast s…
Information readiness and explicit escalation criteria drive MDT streamlining effects more than caseload reduction
New standards help streamline medical team discussions to save time and focus on key patient needs
This mini-review examines standards of care for multidisciplinary team streamlining in the UK. The authors argue that reported effects depen…
Medical teams in England are using new rules to make their meetings faster and more useful. These changes work better when teams are ready w…
Volume doubling time under 200 days marks all malignant nodules in 27 studies of lung cancer screening programs
Nodule growth speed helps assess lung cancer risk in screening programs
This narrative review synthesizes data from 27 studies regarding lung cancer screening programs and nodule features. The authors note that a…
Volume doubling time under 200 days signals higher lung cancer risk, but this indicator must fit into broader risk models for accurate scree…
Review offers broad scope without specific clinical findings or reported limitations
Review of medical studies finds many gaps in reported data
This publication is a review that provides a general overview of a topic. The authors did not report specific conditions, medications, popul…
A new review shows many studies lack key details, making it hard to know what works for patients.
Interval-compressed VDC/IE protocol feasibility and outcomes in 27 Ewing's sarcoma patients at a North African center
Compressed chemotherapy showed mixed results for Ewing's sarcoma patients in a small study.
This retrospective, single-institutional cohort study evaluated an interval-compressed VDC/IE protocol in 27 patients with Ewing's sarcoma t…
A small study found that a compressed chemotherapy regimen for Ewing's sarcoma had high toxicity and low survival rates.
Local brain therapies associated with reduced mortality in HNSCC patients with brain metastasis
Local brain treatments linked to modest survival gains in rare head and neck cancer cases
This retrospective cohort analysis evaluated 201 patients with head and neck squamous cell carcinoma and brain metastasis from three tertiar…
Local brain treatments linked to lower death risk for rare head and neck cancer patients who develop brain metastases, though most still die…
Fianlimab plus cemiplimab showed objective response rates of 20% to 33% in advanced solid tumors during a Phase 1 study.
Early trial shows new cancer drug combo helps some patients with advanced disease
This Phase 1, first-in-human dose-expansion study evaluated fianlimab 1600 mg plus cemiplimab 350 mg in patients with advanced non-small cel…
A new drug combination helped some patients with advanced lung, kidney, head and neck, or skin cancer shrink their tumors in early testing.
WBRT shows no significant survival benefit in thyroid cancer brain metastases meta-analysis
Whole-brain radiation shows no clear survival benefit for thyroid cancer brain metastases
A systematic review and individual patient data meta-analysis of 247 patients with thyroid cancer brain metastases found whole-brain radiati…
Whole-brain radiation therapy showed no clear survival benefit for patients with thyroid cancer that spread to their brain.
Systemic cancer treatment linked to 5% skeletal muscle loss over 90 days
Cancer treatment linked to muscle loss in large analysis
A systematic review and meta-analysis of 78 studies (n=10,502) found that systemic cancer treatment is associated with a small but significa…
Chemotherapy and immunotherapy may cause muscle loss in cancer patients, a new analysis of 78 studies finds.
cGAS–STING activation correlates with improved survival and enhanced checkpoint blockade response in cancer
Activating a cancer-fighting immune pathway can help tumors shrink but too much may backfire
This narrative review synthesizes evidence on cGAS–STING pathway activation in cancer. The authors report that heightened activity correlate…
Turning on a specific immune pathway helps some cancer patients survive longer, yet overactivating it can cause the immune system to stop wo…