Immunoscore stratification shows prognostic value in HPV-associated oropharyngeal cancer
Your Immune System May Predict Throat Cancer Outcomes Better Than Doctors Thought
This international multicenter cohort study validated the Immunoscore (IS) in 191 patients with HPV-associated oropharyngeal squamous cell c…
A new immune scoring tool predicts survival better than standard staging for HPV-related throat cancer, potentially guiding gentler treatmen…
PRISM EHR-based model identifies adults at high risk for pancreatic ductal adenocarcinoma in real-world setting
Your Medical Records Might Flag Pancreatic Cancer Years Before Symptoms Appear
In a prospective multicenter cohort study of 6,282,123 adults, an EHR-based risk model identified individuals at high risk for pancreatic du…
An AI tool using routine health records can flag pancreatic cancer risk up to 3.5 years before symptoms appear in adults 40 and older.
Review describes Virtual Spectral Decomposition framework for cancer imaging analysis
AI Now Reads Tumor Slides Like a Radiologist — and Shows Its Work
This review/commentary outlines a Virtual Spectral Decomposition (VSD) methodological framework for analyzing digital pathology and imaging …
A new AI system reads cancer slides like a doctor and explains exactly which biological features drove each diagnosis.
Review of SIMMA utility for paediatric tumour monitoring via cfDNA profiling and ecDNA detection
A Simple Blood Test May Catch Children's Cancer Relapse Months Early
This review evaluates the clinical utility of the SIMMA single-molecule sequencing approach for profiling circulating and cerebrospinal flui…
A single blood or spinal fluid draw can now map a child's tumor DNA at a level of detail that may warn doctors of relapse long before scans …
Review of WGS integration in Emirati genome program reveals high breast cancer variant prevalence and risk stratification utility
Your DNA May Predict Breast Cancer Risk Decades Before Diagnosis
This observational review analyzes whole-genome sequencing data from 436,780 individuals in the Emirati Genome Program to assess breast canc…
A new genome study shows Arab women face higher breast cancer risks than current tools predict, meaning many may need earlier screening.
Review of non-invasive prehabilitation for neuro-oncology patients at Institut Guttmann in Barcelona
Brain Tumor Surgery Is Terrifying — What If You Could Prepare Your Mind First?
This primary trial review examines a non-invasive prehabilitation (PRH) program in 29 neuro-oncology patients at Institut Guttmann in Barcel…
A pre-surgery wellness program significantly reduced emotional distress and improved quality of life for adults facing brain tumor removal.
Narrative review conceptualizes CVD as systemic immune–metabolic–inflammatory disease
Review suggests immune and metabolic factors drive cardiovascular disease progression
This narrative review synthesizes evidence on cardiovascular disease as a systemic immune–metabolic–inflammatory condition.
Immune and metabolic factors actively drive heart disease progression, offering new ways to assess risk and tailor prevention strategies.
Narrative review examines ulcerative colitis and colorectal cancer risk
Review of ulcerative colitis and colorectal cancer links in patients
This narrative review synthesizes evidence on ulcerative colitis and colorectal cancer risk.
Ulcerative colitis patients face cancer risk driven by inflammation, but better disease control and modern treatments are lowering overall c…
Narrative review discusses high-throughput screening technologies for adoptive T cell therapy optimization
Review of high-throughput screening technologies for adoptive T cell therapy optimization
This narrative review examines high-throughput screening technologies used to optimize adoptive T cell therapy (ACT).
High-throughput screening tools help overcome resistance in adoptive T cell therapy by identifying key targets and substances to boost cance…
Tucidinostat plus capecitabine shows 25.8% response in advanced HR-positive HER2-negative breast cancer
New Drug Combo Helps Breast Cancer After CDK4/6 Failure
This phase 2 trial evaluated tucidinostat plus metronomic capecitabine with endocrine therapy in 66 patients with HR-positive HER2-negative …
A new drug mix shrinks tumors in advanced breast cancer patients whose disease grew after standard treatments failed.
Talquetamab and teclistamab combination shows 79% response in relapsed multiple myeloma with extramedullary disease
Study looks at two antibody drugs for high-risk multiple myeloma
This phase 2 single-arm study evaluated a talquetamab and teclistamab combination in a high-risk population with relapsed/refractory multipl…
A new drug combo for high-risk multiple myeloma helped 79% of patients respond, but 31% faced serious infections and five treatment-related …
Meta-analysis reports high pooled complete response with ALA/MAL photodynamic therapy for superficial BCC
Light vs. Scalpel: New Skin Cancer Data
This PRISMA 2020 systematic review and meta-analysis of 55 studies (2123 patients, 2995 lesions) evaluated ALA-PDT and MAL-PDT for superfici…
Light therapy with cream may match surgery for treating common skin cancer while avoiding scars and functional damage to your face or neck.