Sequential cetuximab-bevacizumab vs bevacizumab-EGFR mAb shows no DDC difference in metastatic CRC
New Drug Order Doesn't Beat Old Standard
A phase III randomized controlled trial in 263 untreated, unresectable wild-type RAS/BRAF metastatic colorectal cancer patients found no dif…
A new drug order for advanced colon cancer did not improve disease control or survival compared to the standard treatment sequence.
Oscillating abrasive device matches curettage and sandpaper for AK skin prep before ADL-PDT
New Tool Makes Sun Damage Treatment Faster
In 22 patients with actinic keratoses undergoing artificial daylight photodynamic therapy, a novel oscillating abrasive skin preparation dev…
This new device makes treating rough sun spots quicker and more comfortable without losing effectiveness.
Becotatug vedotin shows 20.9% objective response in recurrent head and neck squamous cell carcinoma after prior therapy
For patients with advanced head and neck cancer, a new drug showed a 21% response rate in early testing
This multicenter, Phase IIa trial evaluated intravenous becotatug vedotin in 67 patients with recurrent or metastatic squamous cell carcinom…
A new drug shrank tumors in 21% of patients with advanced head and neck cancer who had run out of standard treatment options.
Case report and literature review on concurrent t-AML and LNTB treated with chemoimmunotherapy
Two Rare Diseases Strike After Lung Cancer Treatment
This case report and literature review describes the management of a 54-year-old male with locally advanced lung squamous cell carcinoma, th…
A lung cancer patient treated with chemo and immunotherapy developed two rare diseases simultaneously: a new blood cancer and tuberculosis.
Prolonged nightly fasting plus telehealth coaching showed feasibility in men with prostate cancer on androgen deprivation therapy
Can fasting and coaching help men with prostate cancer feel better and manage weight?
This pilot randomized controlled trial assessed a prolonged nightly fasting plus telehealth coaching intervention (PNF+) versus healthy eati…
Men with prostate cancer on treatment safely tried nightly fasting and coaching, improving quality of life and showing slight weight loss wi…
Phase II RCT finds no benefit for adding capecitabine to 177Lu-Dotatate in advanced NETs
Adding a Drug Actually Hurted These Patients
A Phase II randomized controlled trial in 111 patients with advanced somatostatin receptor-positive GEP or bronchopulmonary NETs compared…
Adding a common chemotherapy drug to cancer treatment actually made tumors grow faster and reduced survival time for these patients.
Pembrolizumab plus chemotherapy versus placebo plus chemotherapy in Chinese adults with advanced biliary tract carcinoma
Could adding pembrolizumab help Chinese adults live longer with advanced biliary tract carcinoma?
This phase 3 randomized controlled trial enrolled 158 Chinese adults with advanced or unresectable biliary tract carcinoma.
A completed study in China compared adding pembrolizumab to chemotherapy for advanced bile duct cancer, tracking how long 158 adults survive…
Subcutaneous PEG-rhG-CSF reduced grade ≥3 neutropenia and CIN in GI cancer patients receiving oral chemotherapy
New Shot Cuts Severe Low White Blood Cell Risk
This prospective, single-center, open-label, exploratory, non-randomized controlled study evaluated subcutaneous PEG-rhG-CSF in 43 gastroint…
A simple shot given before chemotherapy could keep your body's infection-fighting cells strong when taking oral cancer pills.
Case report of semi-implantable IDDS for advanced cancer pain in three patients
Can a small pump stop severe cancer pain in just one day?
This case-based study describes three representative patients with advanced cancer pain treated with a semi-implantable intrathecal drug del…
A small pump delivered direct spinal medicine to three advanced cancer patients, dropping their worst pain from near maximum to zero within …
Meta-analysis shows KRASG12C inhibitors improve outcomes versus chemotherapy in KRAS-mutant NSCLC
New drugs stop lung cancer growth faster than chemo
This meta-analysis evaluated KRASG12C inhibitors versus conventional chemotherapy in 798 patients with KRASG12C-mutant non-small cell lung c…
New drugs targeting a specific lung cancer mutation stop tumor growth faster than standard chemotherapy while causing fewer severe side effe…
Case report of laparoscopic splenectomy with autotransplantation for PILA in a young male
Spleen Mass Mistaken for Benign: Rare Cancer Found in Young Adult
This case report describes a 21-year-old male with papillary intralymphatic angioendothelioma (PILA) treated with laparoscopic total splenec…
Doctors now know to look for a specific rare tumor in young people with spleen lumps, even if tests look normal.
Meta-analysis review synthesizes EDC exposure levels and metabolic markers in patients with PCOS versus controls
Chemicals in Your Body May Trigger PCOS
This meta-analysis review examines endocrine disrupting chemical (EDC) exposure in patients with polycystic ovary syndrome (PCOS) compared t…
Common environmental chemicals found in our daily lives might be silently increasing the risk of polycystic ovary syndrome.