Narrative review suggests time-related biases may attenuate apparent vaccine survival benefits in cancer patients
New math shows vaccine benefits in cancer care might be overstated
This narrative review and target trial emulation examines 3-year overall survival in cancer patients receiving COVID-19 vaccines versus thos…
A new look at the data reveals that timing errors made the vaccine look more powerful than it actually is for cancer patients.
Recurrence patterns in high-grade glioma after standard chemoradiotherapy: a retrospective review
Why tumors grow back inside the radiation beam, not just at the edges
This retrospective single-center review of 41 patients with high-grade glioma found that central recurrence was the most common pattern (36.…
New data shows brain tumors often return in the middle of the radiation zone, suggesting biology, not just targeting errors, drives failure.
Review highlights lack of comprehensive evaluation for atorvastatin anticancer mechanisms and therapeutic potential
Review finds lack of research on atorvastatin's anticancer potential
This narrative review discusses the potential anticancer mechanisms and therapeutic potential of atorvastatin.
A review notes that a comprehensive evaluation of atorvastatin's anticancer mechanisms and potential is currently lacking.
Phase 2 trial of pembrolizumab and DNA vaccines in metastatic prostate cancer shows no significant difference
Prostate Cancer Vaccine Strategy Shows Tumor Responses, But One Arm Adds Risk
This early Phase 2 trial evaluated pembrolizumab combined with pTVG-HP or pTVG-AR DNA vaccines in 60 patients with metastatic castration-res…
A two-vaccine strategy did not improve survival over a single vaccine in advanced prostate cancer, yet both approaches shrank tumors in some…
Double 8F ultrafine chest tubes reduced pain and complications compared to standard tubes in lung tumor patients
Smaller tubes mean less pain for lung tumor patients after surgery
This retrospective multicenter cohort study evaluated 1,076 lung tumor patients who underwent U-VATS.
Lung surgery patients feel significantly less pain and face lower bleeding risks when doctors use ultrafine drainage tubes instead of regula…
LP-184 Alone and With Spironolactone in Recurrent Glioblastoma: Phase 1a Results
New drug combo may help brain cancer patients who have run out of options
This Phase 1a trial in 63 patients (16 with glioblastoma) found LP-184 was well tolerated but with more transaminitis and thrombocytopenia i…
A new drug combination could help brain cancer patients by making their current medicine work much harder inside the tumor.
Modified Banxia Xiexin Decoction plus chemotherapy shows favorable trends in advanced colorectal cancer
Modified herbal decoction may extend survival time for advanced colorectal cancer patients
This randomized controlled trial in 129 patients with advanced colorectal cancer evaluated modified Banxia Xiexin Decoction (mBXD) granules …
Adding a modified herbal decoction to standard cancer treatment might extend survival time and reduce tumor growth in patients with advanced…
Camrelizumab plus nab-paclitaxel showed modest activity in previously treated advanced urothelial carcinoma patients
New Treatment Extends Life for Bladder Cancer Patients
This multicenter Phase II study evaluated camrelizumab plus nab-paclitaxel in 60 patients with advanced urothelial carcinoma who progressed …
For years, Mark, 64, thought he’d beaten cancer.
Colonoscopic Surveillance in Lynch Syndrome Linked to Lower Mortality but Not Reduced Cancer Incidence
Colonoscopies Save Lives in High-Risk Patients
This observational cohort study of 4732 MMR-carriers in the English NHS found that colonoscopic surveillance was associated with decreased C…
You’ve just turned 35. Your mom had colon cancer at 42.
Pembrolizumab adjuvant therapy trial for hepatocellular carcinoma recurrence-free survival
Pembrolizumab May Cut Liver Cancer Return After Surgery
This is a Phase 3 randomized controlled trial in 959 participants with hepatocellular carcinoma who had a complete radiological response aft…
After liver surgery, pembrolizumab may help keep hepatocellular carcinoma from returning, offering new hope for patients with complete tumor…
Narrative review suggests CXCR4 antagonists may target metastatic colorectal cancer via the CXCL12/CXCR4 axis
New review suggests blocking a specific pathway may help fight colorectal cancer spread
This narrative review examines the potential of CXCR4 antagonists, specifically plerixafor and LY2510924, in treating metastatic colorectal …
A fresh look at colorectal cancer shows blocking a specific chemical pathway might stop tumors from spreading and help immune drugs work bet…
Review discusses aptamers and aptamer-drug conjugates for cancer without reported outcomes or safety data
Review of aptamers and aptamer-drug conjugates for cancer treatment
This narrative review examines the use of aptamers and aptamer-drug conjugates in cancer treatment.
A review examines how aptamers and aptamer-drug conjugates may help treat cancer, though details on specific results and patient groups were…