Meta-analysis finds no link between psychosocial factors and most cancer risks
Study links some psychosocial factors to higher lung cancer risk in large data review
This individual-participant data meta-analysis of 22 cohorts (N=421,799) found no association between psychosocial factors and overall cance…
Low social support, being single, or experiencing a loss are linked to higher lung cancer risk, but lifestyle factors like smoking may expla…
Multiple myeloma diagnosis associated with markedly increased hematologic second primary malignancies in 279,894 patients
Multiple myeloma patients show higher risk of second blood cancers, review finds
This systematic review and meta-analysis evaluated second primary malignancy risks in 279,894 patients with multiple myeloma compared to the…
Multiple myeloma patients face a threefold higher risk of developing a second blood cancer compared to the general population, according to …
Systematic review examines angiogenesis-targeting strategies for osteoporosis and fracture healing
Can new ways to boost blood flow help heal broken bones from osteoporosis?
This systematic review evaluated therapeutic strategies targeting angiogenesis, including mesenchymal stem cells, phytochemicals, and repurp…
New blood vessel growth could help heal osteoporosis fractures, but scientists warn we lack clear evidence yet to move these lab findings in…
CD5-positive DLBCL diagnosed in a 74-year-old woman via uterine drainage fluid analysis
Rare uterine lymphoma case highlights need for careful diagnosis in older women
This case report with literature review describes the diagnosis of CD5-positive diffuse large B-cell lymphoma (DLBCL) in a 74-year-old woman…
A rare uterine cancer in a 74-year-old woman mimics common conditions, so doctors must check for specific cell markers to avoid missing the …
Preclinical review finds piperine inhibits cancer cell growth and enhances chemotherapy
Piperine shows promise in lab cancer studies but needs more clinical research
A systematic review of preclinical studies found piperine inhibits cancer cell proliferation, enhances chemotherapy effectiveness, and impro…
Lab studies show piperine stops cancer cell growth and boosts chemotherapy, but poor solubility and no human trials limit its current use.
![Meta-analysis finds [68Ga]Ga-FAPI PET shows high diagnostic accuracy for gynecologic cancers](/assets/images/defaults/oncology-1.jpg)
Meta-analysis finds [68Ga]Ga-FAPI PET shows high diagnostic accuracy for gynecologic cancers
Could a new scan spot breast and ovarian cancer tumors better than the standard test?
A meta-analysis of 253 females with breast, ovarian, and cervical cancers compared [68Ga]Ga-FAPI PET to [18F]F-FDG PET imaging.
A new scan using a different tracer finds breast, ovarian, and cervical cancer tumors and spread much better than the standard test doctors …
Elevated neutrophil-to-lymphocyte ratio predicts brain metastasis risk in lung cancer patients
Could a simple blood test help find who is most at risk for brain metastasis from lung cancer?
This systematic review and meta-analysis evaluated three immune inflammatory markers in 3,643 participants with lung cancer.
A simple blood test showing high inflammation markers can predict who is most likely to develop brain metastasis from lung cancer.
Intratumoral H101 plus total neoadjuvant therapy yields pathologic complete response in one patient with metachronous locally advanced rectal cancer
Could a virus help save a patient's rectal cancer and their ability to use the bathroom?
This case report describes a 50-year-old patient with metachronous locally advanced rectal cancer treated with intratumoral injection of rec…
A virus combined with standard therapy helped a 50-year-old man clear his rectal cancer while keeping his bowel control intact.
EMILIN-1 shows dual tumor-suppressive and promoting roles in brain tumor biology review
Review explores dual role of EMILIN-1 protein in brain tumor biology
A systematic review of experimental data describes EMILIN-1's complex role in nervous system tumors.
A protein called EMILIN-1 might slow brain tumors in some ways but could also change the immune response to help them grow faster.
AI/ML-based miRNA signatures show diagnostic potential for early breast cancer detection
Could a simple blood test help find early breast cancer with high accuracy?
A meta-analysis of 7 studies in patients with early breast cancer found AI/ML-based circulating miRNA signatures achieved a pooled AUC of 0.…
An AI blood test could spot early breast cancer in 81% of cases with 87% accuracy, but mixed study methods mean it should only help doctors …
Simulation study suggests BF-BOLD reduces overdose rates and enhances safety in Phase I trials compared to conventional designs
Can a smarter trial design make early cancer drug tests safer and more sustainable?
This Phase I simulation study compared the Backfill Bayesian Ordered Lattice Design (BF-BOLD) against conventional Phase I trial designs.
A smarter trial design reduces overdose rates and improves safety while preserving drug effectiveness during early cancer tests.
Neoadjuvant chemotherapy plus sintilimab improved response rates versus chemotherapy alone in 61 patients with triple-negative breast cancer
Combination therapy improved response rates in a small study of triple-negative breast cancer patients
This retrospective cohort study evaluated 61 patients with triple-negative breast cancer (TNBC) receiving neoadjuvant therapy at a single ce…
Adding the immunotherapy drug sintilimab to standard chemotherapy boosted response rates and slowed tumor growth in triple-negative breast c…