Autologous hematopoietic stem cell transplantation improves disease-free survival in pediatric extraocular retinoblastoma patients
Children With Eye Cancer Now Have a New Hope for Survival
This retrospective analysis included 12 children with extraocular retinoblastoma treated with autologous hematopoietic stem cell transplanta…
Children with advanced eye cancer can now achieve long-term survival using their own stem cells, especially if the disease has not reached t…
Weekend births linked to longer antibiotic exposure in very low birth weight infants with suspected sepsis
Weekend births delay antibiotic stops for fragile newborns
This retrospective cohort study examined antibiotic exposure times in very low birth weight infants with suspected early-onset sepsis and ne…
New research shows babies born on weekends stay on antibiotics longer than those born during the work week.
Supervised exercise in pediatric oncology: low rate of adverse events over 3 years
Kids with cancer stay active safely with new safety rules
This prospective observational study across six pediatric oncology centers documented 178 adverse events (AEs) in 74,083 supervised exercise…
New safety rules mean kids with cancer can exercise without fear of serious harm
FDA Approves Crysvita (burosumab) for X-Linked Hypophosphatemia and Tumor-Induced Osteomalacia
FDA approves new drug Crysvita for rare bone diseases in children and adults.
FDA approved Crysvita (burosumab) for X-linked hypophosphatemia (XLH) in patients 6 months and older and for tumor-induced osteomalacia (TIO…
The FDA approved Crysvita (burosumab) for X-linked hypophosphatemia (XLH) and tumor-induced osteomalacia (TIO). It is the first treatment th…
Eltrombopag plus immunosuppression for severe aplastic anemia shows clonal evolution patterns
Treatment for severe anemia reveals two paths to cancer risk
This phase 2 observational study followed 204 patients with severe aplastic anemia treated with immunosuppression plus eltrombopag for a med…
New research tracks cancer risks in severe anemia patients treated with standard therapy over five years
Meta-analysis compares robot-assisted versus laparoscopic surgery for pediatric choledochal cyst.
Robotic surgery cuts complications in kids’ liver surgery
This meta-analysis of retrospective studies in children with choledochal cyst found robot-assisted surgery associated with lower rates of bi…
Kids who had robotic surgery for a rare liver cyst faced far fewer serious complications than those who had standard keyhole surgery, a new …
Fetal paracetamol exposure linked to reduced ovarian and uterine volume in girls
Prenatal Paracetamol Linked to Smaller Ovaries and Uterus in Girls
This prospective, observational cohort study examined 3425 eligible participants, including 302 girls examined at follow-up. Fetal exposure …
Prenatal paracetamol exposure is linked to smaller ovaries and uterus in infant girls, raising new questions about long-term reproductive he…
Case report and literature review on mosaic DICER1 mutations and disease stability in a 6-month-old boy
One Baby, Five Tumors, One Tiny Gene Change
This case report and literature review describes a 6-month-old boy with mosaic DICER1 RNase IIIb hotspot mutation and multiple tumors. The a…
A 6-month-old boy developed five different tumors linked to one small gene change, showing how one mutation can drive multiple childhood can…
Systematic review and meta-analysis compares ESIN versus plating for pediatric femoral shaft fractures
Elastic Nails Beat Plates for Kids’ Broken Thigh Bones
This systematic review and meta-analysis evaluates elastic stable intramedullary nailing (ESIN) versus plating for patients ≤18 years with d…
Kids with broken thigh bones recover faster and with fewer setbacks when treated with elastic nails instead of metal plates, a major review …
Long peripheral catheters reduce infusion failure compared to short catheters in late preterm and term neonates.
Long IVs Beat Short Tubes for Newborns Needing Medicine
This single-center retrospective cohort study evaluated 197 eligible neonates (gestational age ≥34 weeks and birth weight ≥1,500 g) receivin…
Longer IV catheters failed less often than short ones in newborns needing short-term treatment, cutting failure rates nearly in half.
Woodward procedure associated with improved outcomes in pediatric Sprengel deformity patients.
Surgery lifts high shoulder blades in children with great results
This retrospective analysis evaluated 13 pediatric patients with unilateral Sprengel deformity undergoing the Woodward procedure. Outcomes i…
New findings show children with a high shoulder blade from birth can move better and look more normal after surgery is performed by a specia…
GI multiplex PCR testing in children with acute gastroenteritis showed high positivity and guided antibiotic stewardship.
New test cuts guesswork in children’s stomach bugs and changes antibiotic use
This retrospective observational study evaluated GI multiplex PCR testing in 276 children aged ≤14 years admitted with gastroenteritis at a …
A rapid stool test identified the cause in 91% of children with stomach bugs and helped doctors start or stop antibiotics more precisely.