Benzodiazepines increase delirium and sleep fragmentation risk while dexmedetomidine shows mixed evidence in pediatric ICU
Sedation Choices May Impact Brain Health in Critically Ill Children
This narrative review examines sedation practices and neurocognitive outcomes in critically ill infants and children. It suggests benzodiaze…
Choosing different sedative medications for children in intensive care may impact their sleep quality and long-term brain health.
Nalmefene reduces sufentanil-induced cough incidence to 11.3% at 0.1 μg/kg in children
Nalmefene reduces cough from sufentanil in children
This randomized controlled trial of 249 children aged 1–6 years undergoing elective laparoscopic surgery found that nalmefene significantly …
A low dose of nalmefene cut cough rates from 46% to 11% in young children getting sufentanil for surgery.
Imatinib achieves complete cytogenetic response in a pediatric patient with suspected chronic myeloid leukemia
Imatinib works for CML in child with high platelets
This case report describes a pediatric patient with isolated thrombocytosis who achieved a complete cytogenetic response to imatinib after f…
A child with high platelets and no response to standard therapy was found to have CML and responded to imatinib.
Blood product removal reduces permanent shunting risk and mortality in infants with posthemorrhagic hydrocephalus
Blood Product Removal Shows Lower Risks for Preterm Infants
This meta-analysis of 256 preterm infants with intraventricular hemorrhage and posthemorrhagic hydrocephalus found that blood product remova…
A meta-analysis suggests blood product removal may lower mortality and infection rates in preterm infants with specific brain conditions.
Obstructive Sleep Apnea Affects Nearly Half of Cystic Fibrosis Patients
Nearly half of people with cystic fibrosis have sleep apnea
A meta-analysis finds that 48% of cystic fibrosis patients have obstructive sleep apnea, linked to worse lung function and oxygen levels.
Almost half of all people with cystic fibrosis also live with obstructive sleep apnea, a condition that can impact oxygen and lung function.
Predictors of Polysomnography Progression in Children with Mild Sleep-Disordered Breathing
Certain risk factors may signal when children need surgery sooner
Identifying specific risk factors like ADHD and asthma can help clinicians determine which children with mild sleep-disordered breathing req…
New data shows that conditions like asthma and ADHD can make it more likely that a child's snoring and breathing issues will worsen over tim…
Meta-analysis reveals significant disparities in childhood anthropometric failure across global regions
Childhood Undernutrition Rates Show Progress in Low and Middle Income Countries
A large-scale meta-analysis identifies high rates of nutritional failure in children under five, highlighting severe inequalities based on w…
While childhood undernutrition rates are declining globally, many children in rural areas and poorer households still face significant nutri…
Trained general practitioners achieve substantial agreement with radiologists in abdominal aortic aneurysm ultrasound screening
General practitioners can accurately screen for abdominal aortic aneurysms
This multiregional pilot study evaluates the feasibility of abdominal aortic aneurysm screening performed by general practitioners in primar…
A new pilot study shows that general doctors can reliably use ultrasound to find abdominal aortic aneurysms in a primary care setting.
Oxytocin use and high newborn weight are associated with increased episiotomy risk during vaginal birth
Oxytocin use and newborn weight linked to higher episiotomy risk
This meta-analysis of 17,502 individuals undergoing vaginal birth identifies oxytocin use and newborn weight as significant risk factors for…
New data shows that oxytocin use and heavier newborn weights are linked to a higher risk of an episiotomy during vaginal birth.
Short-course antibiotics cut complication risk by half in pediatric osteoarticular infections
Short Antibiotic Courses May Lower Risks for Children with Bone Infections
This meta-analysis of 2240 pediatric patients found that short-course antibiotic treatment for uncomplicated osteoarticular infections was a…
Children with uncomplicated bone infections may face fewer complications when treated with a shorter course of antibiotics instead of long-t…
Behavioral therapy produces sustained improvements in tic symptoms for children and adolescents with Tourette syndrome
Behavioral therapy eases tics in children with Tourette syndrome
This meta-analysis of randomized controlled trials involving 942 participants found that behavioral therapy significantly improves tic sympt…
A new analysis shows behavioral therapy reduces tic symptoms in kids with Tourette syndrome, and the benefits last.
Single-stage reconstruction shows no significant difference compared to staged reconstruction for bowel continence
Single and staged surgery show similar results for bowel control
This meta-analysis of 746 neonates with anorectal malformations found no significant difference in bowel continence between single-stage and…
New analysis of 746 infants shows that both one-stage and multi-stage surgeries result in similar levels of bowel control.