Leuprolide acetate associated with final adult height exceeding mid-parental height in girls with central precocious puberty
More Than Half of Girls on Puberty Therapy Beat Their Genetic Height Potential
This retrospective cohort study included 73 girls with central precocious puberty or early puberty treated with depot leuprolide acetate. Th…
More than half of girls treated for early puberty ended up taller than their genetic prediction, with younger age at treatment being the key…
Meta-analysis of ketamine versus other analgosedatives in critically ill children receiving invasive mechanical ventilation
Ketamine cuts opioid use in ventilated kids
This systematic review and meta-analysis evaluated continuous ketamine infusion compared with other analgosedatives in critically ill childr…
A new analysis suggests ketamine could help reduce opioid use in children on breathing machines, offering a safer path to pain control in in…
L9LS monoclonal antibody reduces malaria infection in children in western Kenya
A malaria shot for babies shows real protection in Kenya
This randomized controlled trial evaluated the L9LS monoclonal antibody in infants and children in a high perennial malaria transmission set…
A long-acting antibody shot reduced malaria infections by 43% in young children in Kenya, with no major safety concerns.
Burosumab improves phosphate levels in 12 children and adults with fibrous dysplasia over 48 weeks.
Burosumab Restores Phosphate Balance in Rare Bone Disease
This Phase 2 trial enrolled 12 participants (7 children, 5 adults) with fibrous dysplasia to assess burosumab. At 48 weeks, 100% achieved ph…
A drug already used for rare phosphate disorders may finally offer real relief for people with fibrous dysplasia, a painful bone condition t…
PGx testing with education improved understanding and perceived utility compared to test results alone in a randomized trial.
Adding a video and counseling helps families understand genetic test results better.
This single-center randomized control trial involved pregnant individuals and families or guardians of children with a chronic health condit…
Giving families a video and extra counseling alongside genetic test results improved their understanding and made the tests feel more useful…
Narrative review on pediatric RSV co-infections and post-pandemic rebound
RSV Hits Kids Harder When Another Bug Joins In
This narrative review synthesizes evidence on pediatric RSV co-infections in a global context. It finds co-infections are frequent, associat…
It started with a sniffle. Then a cough. By day three, 7-month-old Mia was breathing fast, ribs pulling in with each breath.
Systematic review and meta-analysis of vosoritide in children with achondroplasia shows growth gains and injection site reactions
New Treatment Linked to Faster Growth in Children With Achondroplasia
This systematic review and single-arm meta-analysis evaluated vosoritide in children with genetically confirmed achondroplasia across 13 stu…
A new review shows a specific drug can help children with achondroplasia grow taller over one year.
Decision-support model predicts failed closed reduction in pediatric supracondylar humerus fractures
New tool predicts when broken arm fixes will fail in children
This multicenter retrospective cohort study evaluated a decision-support model in 179 pediatric patients with supracondylar humerus fracture…
A new model predicts which children need surgery for broken arms, helping doctors prepare better before the operation starts.
Radiomics features on MRI discriminate sellar LCH from tumor marker-negative GCTs with an AUC of 0.81.
AI Scan Helps Doctors Spot Confusing Brain Tumors
This retrospective cohort study evaluated 93 patients with sellar region tumors to discriminate between Langerhans cell histiocytosis (LCH) …
A new computer system helps doctors tell two similar brain tumors apart using MRI scans.
Narrative review examines high-risk factors and major nursing interventions for bronchopulmonary dysplasia in premature infants.
Nursing care and risk factors for lung disease in premature babies
This narrative review addresses high-risk factors for bronchopulmonary dysplasia and major nursing interventions in premature infants. The a…
This review looks at how nursing interventions and high-risk factors affect premature infants with bronchopulmonary dysplasia, offering insi…
Early enteral feeding during hypothermia for neonatal HIE shows no GI adverse event link
Early feeding during baby cooling therapy appears safe
This single-center retrospective cohort study of 94 neonates with moderate to severe hypoxic-ischemic encephalopathy (HIE) undergoing therap…
In 94 newborns with brain injury, early feeding during cooling therapy did not raise gut problems and was linked to shorter nutrition suppor…
Review of RANBP2 variant carriers shows exaggerated TNF- responses and distinct immunologic signature in acute necrotizing encephalopathy.
A specific gene mutation creates a unique immune warning sign for a rare brain disease.
This prospective biological study review examines 23 heterozygous carriers of the RANBP2 c.1754C>T (p.Thr585Met) variant and 28 noncarriers.…
A rare gene mutation creates a unique immune warning sign that could help doctors protect children from severe brain infections sooner.