Preterm birth linked to higher pain intensity and heat pain thresholds in meta-analysis
Preterm birth may be linked to higher pain levels in adults
This meta-analysis of 731 participants found that individuals born preterm report higher pain intensity and have higher heat pain thresholds…
People born prematurely may experience different sensations of heat and pain as they grow into adulthood.
Lower lip capillary malformation occurs in all patients with CLAPO syndrome
CLAPO syndrome: Lower lip marks seen in all 31 patients
This case report and retrospective review analyzes 31 patients with CLAPO syndrome. The authors identify lower lip capillary malformation as…
A rare syndrome always includes a lower lip mark, new review of 31 cases finds.
Aerobic exercise reduces subthreshold depressive symptoms in adolescents compared to psychoeducation
Aerobic exercise helps reduce mild depression symptoms in teenagers
This secondary analysis of a randomized clinical trial involving 206 adolescents with subthreshold depressive symptoms found that aerobic ex…
A new study shows that a year of aerobic exercise can improve mood and brain connectivity in teens with early signs of depression.
Osteopetrosis in children: orthopaedic management guided by bone brittleness and fracture risk
Osteopetrosis in children: what orthopaedic surgeons need to know
This narrative review summarizes existing literature on osteopetrosis to guide orthopaedic surgeons in establishing treatment protocols for …
Bones that are too dense can break easily. A new review explains how to treat fractures in kids with this rare condition.
Observational survey identifies determinants of Infant and Young Child Feeding practices in children with SAM
Factors Influencing Healthy Feeding Practices for Children with Severe Malnutrition
This observational pre-trial baseline survey involved 486 children aged 6 to 23 months with severe acute malnutrition (SAM) in Ethiopia. The…
New data identifies key factors that help children in Ethiopia get the proper nutrients needed to recover from severe malnutrition.
Long-term relapse rate in children with convulsions and mild gastroenteritis is 9.8% (95% CI 5.2%-17.7%)
Children with Convulsions during Gastroenteritis May Face Relapse Risks
This meta-analysis of 3,302 children with convulsions and mild gastroenteritis found a long-term relapse rate of 9.8%. While acute seizure c…
A review of over 3,000 children shows that while long-term relapses are uncommon, certain factors like age and family history may play a rol…
Lactobacillus rhamnosus GG does not significantly impact composite outcomes in VLBW infants
Trial shows probiotic LGG does not improve outcomes for infants
This randomized controlled trial of 236 enterally-fed very low birth weight infants found no significant difference in the primary composite…
A trial of 236 very low birth weight infants found that a specific probiotic did not reduce risks like sepsis or intestinal issues.
Rotarix PCV-free meets non-inferiority for seroconversion rates compared to Rotarix in infants
Trial Shows Rotarix PCV-free is Comparable to Rotarix for Infants
This Phase III randomized controlled trial evaluated 2000 healthy Chinese infants aged 6 to 16 weeks. Rotarix PCV-free demonstrated non-infe…
A large trial shows that the Rotarix PCV-free vaccine provides similar protection against rotavirus as the standard Rotarix vaccine in infan…
Caesarean birth and perinatal antibiotics are associated with reduced gut microbial diversity
Birth method and antibiotics impact infant gut bacteria variety
This meta-analysis of 5,309 healthy term infants found that while bacterial abundance differences between vaginal and caesarean births were …
New research explores how vaginal birth versus C-sections and early antibiotic use shape the essential bacteria in a baby's developing gut.
Liquefied petroleum gas cookstove intervention showed no significant effect on infant early child development
Switching to cleaner cookstoves did not change infant development scores
This randomized controlled trial evaluated the impact of liquefied petroleum gas (LPG) cookstoves on early child development in pregnant wom…
A large study across four countries found that switching to cleaner stoves did not improve general early childhood development scores for in…
SQ-LNS reduces hair cortisol concentration in children of mothers with limited schooling
Nutrient Supplements May Lower Stress Markers in Some Children
This randomized controlled trial of 680 children in Ghana found no overall difference in hair cortisol concentration between SQ-LNS and cont…
A trial in Ghana suggests that specific nutrient supplements may lower stress markers in children whose mothers have less formal education.
Maternal age, BMI, and irregular folic acid supplementation are associated with higher birth defect risk
Factors like age and folic acid impact risk of birth defects
This meta-analysis of 25 studies involving 26,019 cases in China identifies several maternal and environmental factors associated with birth…
New data shows how maternal age, weight, and consistent folic acid use can influence the risk of birth defects in newborns.