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Pediatrics

386 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
PGx testing with education improved understanding and perceived utility compared to test results alone in a randomized trial.
Pediatrics RCT
PGx testing with education improved understanding and perceived utility compared to test results alone in a randomized trial. Adding a video and counseling helps families understand genetic test results better.
This single-center randomized control trial involved pregnant individuals and families or guardians of children with a chronic health condit…
Giving families a video and extra counseling alongside genetic test results improved their understanding and made the tests feel more useful…
Narrative review on pediatric RSV co-infections and post-pandemic rebound
Pediatrics Sys. Review
Narrative review on pediatric RSV co-infections and post-pandemic rebound RSV Hits Kids Harder When Another Bug Joins In
This narrative review synthesizes evidence on pediatric RSV co-infections in a global context. It finds co-infections are frequent, associat…
It started with a sniffle. Then a cough. By day three, 7-month-old Mia was breathing fast, ribs pulling in with each breath.
Systematic review and meta-analysis of vosoritide in children with achondroplasia shows growth gains and injection site reactions
Pediatrics Meta-analysis
Systematic review and meta-analysis of vosoritide in children with achondroplasia shows growth gains and injection site reactions New Treatment Linked to Faster Growth in Children With Achondroplasia
This systematic review and single-arm meta-analysis evaluated vosoritide in children with genetically confirmed achondroplasia across 13 stu…
A new review shows a specific drug can help children with achondroplasia grow taller over one year.
Decision-support model predicts failed closed reduction in pediatric supracondylar humerus fractures
Pediatrics Cohort
Decision-support model predicts failed closed reduction in pediatric supracondylar humerus fractures New tool predicts when broken arm fixes will fail in children
This multicenter retrospective cohort study evaluated a decision-support model in 179 pediatric patients with supracondylar humerus fracture…
A new model predicts which children need surgery for broken arms, helping doctors prepare better before the operation starts.
Radiomics features on MRI discriminate sellar LCH from tumor marker-negative GCTs with an AUC of 0.81.
Pediatrics Cohort
Radiomics features on MRI discriminate sellar LCH from tumor marker-negative GCTs with an AUC of 0.81. AI Scan Helps Doctors Spot Confusing Brain Tumors
This retrospective cohort study evaluated 93 patients with sellar region tumors to discriminate between Langerhans cell histiocytosis (LCH) …
A new computer system helps doctors tell two similar brain tumors apart using MRI scans.
Narrative review examines high-risk factors and major nursing interventions for bronchopulmonary dysplasia in premature infants.
Pediatrics Sys. Review
Narrative review examines high-risk factors and major nursing interventions for bronchopulmonary dysplasia in premature infants. Nursing care and risk factors for lung disease in premature babies
This narrative review addresses high-risk factors for bronchopulmonary dysplasia and major nursing interventions in premature infants. The a…
This review looks at how nursing interventions and high-risk factors affect premature infants with bronchopulmonary dysplasia, offering insi…
Early enteral feeding during hypothermia for neonatal HIE shows no GI adverse event link
Pediatrics Cohort
Early enteral feeding during hypothermia for neonatal HIE shows no GI adverse event link Early feeding during baby cooling therapy appears safe
This single-center retrospective cohort study of 94 neonates with moderate to severe hypoxic-ischemic encephalopathy (HIE) undergoing therap…
In 94 newborns with brain injury, early feeding during cooling therapy did not raise gut problems and was linked to shorter nutrition suppor…
Review of RANBP2 variant carriers shows exaggerated TNF- responses and distinct immunologic signature in acute necrotizing encephalopathy.
Pediatrics
Review of RANBP2 variant carriers shows exaggerated TNF- responses and distinct immunologic signature in acute necrotizing encephalopathy. A specific gene mutation creates a unique immune warning sign for a rare brain disease.
This prospective biological study review examines 23 heterozygous carriers of the RANBP2 c.1754C>T (p.Thr585Met) variant and 28 noncarriers.…
A rare gene mutation creates a unique immune warning sign that could help doctors protect children from severe brain infections sooner.
Prophylactic azithromycin during labor increases S. aureus resistance in mothers and infants
Pediatrics RCT
Prophylactic azithromycin during labor increases S. aureus resistance in mothers and infants Azithromycin in Labor Raises Short-Term Resistance Risk
This RCT sub-study of 911 women and 915 infants found that prophylactic oral azithromycin during labor increased azithromycin resistance in …
This could change how we balance infection protection and antibiotic safety in childbirth.
Network meta-analysis finds medium-dose vitamin A superior to high-dose for pediatric pneumonia.
Pediatrics Meta-analysis
Network meta-analysis finds medium-dose vitamin A superior to high-dose for pediatric pneumonia. Medium-dose vitamin A may help children with pneumonia recover faster
This network meta-analysis of trials in children with pneumonia synthesized evidence on vitamin A supplementation doses. It found medium-dos…
For children with pneumonia, medium doses of vitamin A appear to shorten fever and cough duration better than high doses, though evidence ha…
Esketamine vs fentanyl for pediatric tonsillectomy pain shows comparable FLACC scores
Pediatrics RCT
Esketamine vs fentanyl for pediatric tonsillectomy pain shows comparable FLACC scores Esketamine and fentanyl ease kids' tonsil pain equally after surgery
This randomized controlled trial in 54 children scheduled for tonsillectomy compared esketamine 0.5 mg·kg to fentanyl 4 μg·kg at induction. …
For kids getting tonsils out, esketamine and fentanyl control pain just as well, but esketamine keeps blood pressure steadier during surgery…
Telemedicine family care guidance improves neurodevelopment in premature infants
Pediatrics RCT
Telemedicine family care guidance improves neurodevelopment in premature infants Tiny Babies, Big Gains: How Video Calls Help Preemies Thrive
This randomized controlled trial of 186 premature infants found that telemedicine-based family care guidance significantly improved Bayley S…
A new study shows that regular video calls with nurses can significantly improve how premature babies grow and learn after leaving the hospi…