FDA Approves Rexulti (brexpiprazole) for Agitation in Alzheimer's Dementia
FDA approves Rexulti to treat agitation in Alzheimer's patients
FDA approved Rexulti (brexpiprazole) for treatment of agitation associated with dementia due to Alzheimer's disease. It is not indicated for…
The FDA approved Rexulti (brexpiprazole) to treat agitation in people with Alzheimer's disease. This is a new option for managing this chall…
FDA Approves Auvelity (dextromethorphan/bupropion) for Major Depressive Disorder and Agitation in Alzheimer's
FDA approves new drug Auvelity for depression and Alzheimer's agitation.
The FDA approved Auvelity (dextromethorphan/bupropion) for major depressive disorder (MDD) and agitation associated with dementia due to Alz…
The FDA approved Auvelity for major depressive disorder and agitation in Alzheimer's disease. It combines two medicines into one pill. This …
Systematic review and meta-analysis of vaping prevention messages for adolescents and young adults
Vaping prevention messages help teens feel less likely to try nicotine products
This meta-analysis synthesized evidence from 11,235 adolescents and young adults on campaign-related vaping prevention messages. It found a …
A review of prevention campaigns shows these messages make young people feel vaping is riskier. They also lower how likely teens say they ar…
Schizophrenia linked to higher heart rate and QT dispersion in meta-analysis
Adults with schizophrenia show higher heart rates and different heart electrical signals compared to healthy people in this large review
A meta-analysis of 5,648 schizophrenia patients and 23,636 controls found significantly higher heart rate and QT dispersion, suggesting incr…
A big review of studies found that adults with schizophrenia have faster heart rates and different electrical signals than healthy people. T…
Meta-analysis finds high anxiety and depression prevalence in pediatric inflammatory bowel disease
Anxiety and depression are common in young people with inflammatory bowel disease
This meta-analysis synthesized data on anxiety and depression in children and adolescents with inflammatory bowel disease. It found pooled p…
About one in eight young people with IBD have anxiety symptoms, and one in seven have depression symptoms, a new analysis shows.
Scoping review examines home-based digital health in rural Canadian healthcare settings
Digital health at home could close Canada’s rural care gap
This scoping review synthesizes evidence from sixteen studies regarding home-based digital health technologies in rural or remote Canadian c…
For millions in remote Canada, slow internet and long drives to clinics have made health care a struggle, but new home tech could finally br…
GLP-1RAs reduce weight and HbA1c in severe mental illness with low discontinuation rates
New drugs help people with severe mental illness lose weight safely
This systematic review and meta-analysis evaluated glucagon-like peptide-1 receptor agonists in individuals with severe mental illness who h…
New weight loss drugs work well and stay safe for people with severe mental illness who struggle with obesity and high blood sugar.
Diffusion tensor imaging shows lower fractional anisotropy in bipolar disorder white matter tracts
Bipolar Brain Wiring Shows Clear Damage in Key Emotional Pathways
This systematic review and meta-analysis of diffusion tensor imaging studies compared 5,372 individuals with bipolar disorder to 6,240 healt…
Brain scans reveal consistent white matter damage in bipolar disorder, especially in tracts that regulate emotion and connect brain hemisphe…
Clozapine Use Linked to Higher SARS-CoV-2 Infection Risk in Severe Mental Disorders
Clozapine users faced higher risk of severe COVID-19 in large study
A meta-analysis of 155,945 outpatients with severe mental disorders found that clozapine users had a higher rate of SARS-CoV-2 infection com…
A massive analysis of over 155,000 people found that those taking clozapine had higher rates of infection and worse outcomes from COVID-19.
Preoperative psychological factors are associated with postoperative cognitive outcomes in older adults
Psychological factors linked to cognitive issues after surgery in older adults
This systematic review and meta-analysis examined preoperative psychological factors in older adults aged 60 years or older.
A large review links preoperative anxiety and stress to worse cognitive outcomes after surgery for older patients.
Semaglutide improves physical quality of life in schizophrenia with prediabetes
Semaglutide improves physical quality of life in adults with schizophrenia and obesity
This secondary analysis of a randomized trial in 154 adults with schizophrenia, prediabetes, and overweight or obesity found that once-weekl…
A secondary analysis of a trial found that once-weekly semaglutide improved physical quality of life in adults with schizophrenia and obesit…
Meta-analysis finds decreased GDNF levels in bipolar disorder but high heterogeneity limits conclusions
Brain chemical levels differ in bipolar disorder compared to healthy people
This meta-analysis of 825 patients with bipolar disorder (BD) and 885 healthy controls found significantly lower circulating GDNF levels in …
A large review found lower levels of a specific brain chemical in people with bipolar disorder. This difference was clear even when comparin…