Case-control study links impaired decision-making tasks to suicide attempts in depressed patients
Can't weigh risks and rewards? Suicide attempters show different decision-making patterns
This case-control study assessed 132 depressed patients with suicide attempts, patient controls, and healthy controls using clinical decisio…
People who attempted suicide weigh risks differently, showing less fear of loss and more impulsive errors that link directly to higher suici…
Narrative review of TRD epidemiology and CYP2C19 genotypes in Pakistan
New Clue Reveals Why Depression Meds Fail Some People
This narrative review summarizes a genetic epidemiological study in Pakistan involving 3677 adults with major depressive disorder.
A major study shows that genes and family support are key to treating depression.
Comparative evaluation of simulated reasoning and self-verification for LLM psychiatric diagnosis
Study evaluates AI models for psychiatric diagnosis using case vignettes
This comparative evaluation assessed simulated reasoning and self-verification prompts for large language models using 106 psychiatric case …
AI models that check their own reasoning improved accuracy in diagnosing psychiatric disorders from case vignettes, though sensitivity gains…
Longitudinal MRI study links brain morphometry to treatment in schizophrenia spectrum disorders
Long-Term Schizophrenia Treatment May Reshape Brain Structure, Study Shows
This observational cohort study analyzed longitudinal structural MRI data from 350 individuals with schizophrenia spectrum disorders and 193…
Time spent on schizophrenia medication physically reshapes brain structure, linking treatment duration to lasting changes in the mind's orga…
Narrative review explores psychobiotics and lifestyle changes for chronic constipation-depression comorbidity
Your Gut and Your Mood Are Talking — Here's What They're Saying
This narrative review examines potential strategies for managing chronic constipation and depression comorbidity, including psychobiotics, f…
Chronic constipation and depression often share a common cause: gut bacteria imbalances that disrupt the signals between your digestive syst…
Meta-analysis reviews parent-mediated intervention for infants at elevated autism risk
Teaching Parents a Skill That Could Change Their Baby's Developmental Path
This meta-analysis synthesizes evidence from eleven studies regarding parent-mediated early intervention for infants and toddlers at elevate…
Giving parents specific tools to engage with their infants before an autism diagnosis may help shape how the brain develops during the most …
Chinese female patients with anorexia nervosa showed no significant gut microbiota differences versus healthy controls
The Gut-Brain Link in Anorexia Is Real — But More Complicated Than Expected
This cohort study compared gut microbiota profiles in 30 female patients with anorexia nervosa (AN) and 30 sex- and age-matched healthy cont…
Women with anorexia nervosa have different gut bacteria than healthy people, but these microbes don't predict illness severity or childhood …
Preoperative anxiety/depression linked to poorer outcomes in equinocavovarus foot surgery
Your Mindset Before Surgery Can Change How Well You Heal
A cohort study of 103 adult patients with equinocavovarus foot deformity at Xi'an Honghui Hospital found those with preoperative anxiety/dep…
Nearly half of foot surgery patients had anxiety or depression before the operation, and those patients ended up with more pain and less phy…
Twice-weekly telemedicine home ultrasound reduces anxiety in pregnant patients with prior late pregnancy loss
Seeing your baby move on a screen in your own living room can change everything. For many women who have lost a late pregnancy, the fear of losing that baby again is a heavy weight. This study shows that bringing the ultrasound home helps lift that weight
This quasi-randomized trial evaluated twice-weekly telemedicine home ultrasound sessions versus standard high-risk care in 50 pregnant patie…
Women who lost a late pregnancy feel less fear and worry more about their baby when they see it moving on a home ultrasound twice a week.
Veggie Van mobile produce market model evaluated in lower-income US communities over 12 months
Can mobile markets bring fresh food to lower-income neighborhoods in the United States?
This protocol describes a process evaluation of the Veggie Van (VV) model, a mobile produce market intervention, in lower-income communities…
A mobile market project tested how well fresh produce vans operate in new locations across the United States to help lower-income neighborho…
FDA Approves Spravato (esketamine) for Treatment-Resistant Depression and Depressive Symptoms with Acute Suicidal Ideation in Adults
The FDA approved a new nasal spray called Spravato for severe depression
The FDA approved Spravato (esketamine) for treatment-resistant depression in adults as monotherapy or with an oral antidepressant, and for d…
FDA approved a new nasal spray for severe depression when other treatments fail or when patients face acute suicidal thoughts.
PETRUSHKA decision-support tool reduced treatment discontinuation and improved symptoms in major depressive disorder
The Algorithm That Helps Doctors Pick the Right Antidepressant for You
This randomized clinical trial evaluated an evidence-based clinical decision-support system called PETRUSHKA against usual care in adults wi…
A new web-based tool helps doctors pick the right antidepressant, cutting discontinuation rates by nearly 40% and helping patients stay on t…