Multicomponent breathing and exercise program improves breathlessness mastery in moderate to severe COPD
New Breathing Program Helps COPD Patients Regain Control Over Daily Life
In this randomized controlled trial of 113 patients with moderate to severe COPD and disabling breathlessness, an 8-week multicomponent inte…
An 8-week coaching program helps severe COPD patients control breathlessness and reduce daily discomfort without relying only on medication.
Narrative review examines lung microbiome and mucosal IgA in chronic inflammatory lung diseases
Your Lungs Have Their Own Microbiome — and It Affects Your Immune Defenses
This narrative review explores the interplay between the lung microbiome and mucosal immunoglobulin A system in chronic inflammatory lung di…
The lung's microbiome and immune protein IgA work together to protect health, and their breakdown drives chronic lung diseases like asthma a…
Review of preclinical EVs for sepsis-associated acute lung injury
Lungs Heal Themselves Using Body’s Own Repair System
This narrative review examines extracellular vesicles (EVs) and EV-inspired biomimetic nanosystems as a potential therapeutic approach for…
Tiny cell bubbles calm deadly lung inflammation in sepsis, offering a new way to help the body fix its own lungs during severe infections.
Feasibility study abstract evaluates home spirometry and FeNO for asthma diagnosis in adults
Home Testing Tools Show Potential for Asthma Diagnosis in Adults
This abstract reports a feasibility study evaluating home spirometry and fractional exhaled nitric oxide (FeNO) monitoring for asthma diagno…
Home breathing and airway tests showed high accuracy for diagnosing asthma in adults, potentially cutting the need for invasive clinic chall…
Umbilical cord-derived mesenchymal stromal cells for severe COVID-19 ARDS show qualitative improvement and tolerability
Fresh Cells Help Severe Lungs Recover
This randomized controlled trial summary included 37 patients with severe COVID-19 acute respiratory distress syndrome receiving freshly cul…
Freshly cultured cells from umbilical cords helped patients with severe COVID-19 lung damage recover faster and feel better for months.
Hospitalized COVID-19 patients receiving antiviral, antiretroviral, or immunosuppressive treatments showed variable outcomes
What helps hospitalized COVID-19 patients survive? A new model offers clues
This cohort study of 711 hospitalized subjects with coronavirus evaluated antiviral, antiretroviral, and immunosuppressive treatments.
When COVID-19 hits hard, doctors need better tools to predict who might get worse.
LSTM-based model showed improved ventilator triggering metrics compared to Auto-Trak in a small trial
Smarter Ventilators May Finally Breathe in Sync With You
This clinical trial evaluated an LSTM-based model versus an Auto-Trak model for ventilator triggering control in 10 volunteers and 5 patient…
A new AI-powered breathing machine controller may reduce the dangerous mismatch between a ventilator's rhythm and a patient's own breathing …
![In a phase 2 trial, [Ga]Ga-SSO120 PET/CT detected malignancies in 18 of 19 patients with small cell or large cell neuroendocrine lung cancer](https://images.unsplash.com/photo-1766297247924-6638d54e7c89?crop=entropy&cs=tinysrgb&fit=max&fm=jpg&ixid=M3w5MDg5NDR8MHwxfHNlYXJjaHw5fHxtZWRpY2FsJTIwcmVzZWFyY2glMjBzY2llbmNlfGVufDF8MHx8fDE3NzU4ODUyMzd8MA&ixlib=rb-4.1.0&q=80&w=1080)
In a phase 2 trial, [Ga]Ga-SSO120 PET/CT detected malignancies in 18 of 19 patients with small cell or large cell neuroendocrine lung cancer
A New Scan That Lights Up Hidden Lung Cancer Spread
This prospective, phase 2, cross-sectional imaging trial evaluated [Ga]Ga-SSO120 PET/CT versus CT in 19 patients with small cell lung cancer…
A new kind of PET scan found hidden tumors in patients with aggressive lung cancer, including bone and brain spread that standard imaging mi…
SABR shows 46% 5-year overall survival in unfit NSCLC patients in phase 2 trial
Precision Radiation Offers a Real Option for Lung Cancer Patients Who Can't Do Chemo
A non-randomized phase 2 trial of 50 patients with unresectable locally advanced NSCLC unfit for concurrent chemoradiation found 5-year over…
Nearly half of patients treated with precision radiation were still alive at five years, offering hope for lung cancer patients too frail fo…
AI nomogram predicts malignancy risk in surgically resected pulmonary nodules ≤3 cm
AI tool predicts cancer risk in lung nodules removed for surgery
This retrospective cohort study internally validated an AI-assisted clinico-quantitative imaging nomogram in 951 patients undergoing resecti…
An AI tool predicts cancer risk in lung nodules removed for surgery, showing a 95% chance of malignancy for high-risk cases and a 43% chance…
Spirometry restriction linked to higher interstitial lung disease and mortality risk in a large cohort
Does normal breathing test results hide serious lung disease that leads to higher death rates?
This retrospective cohort study of 47,597 patients with normal spirometry from four pulmonary diagnostic labs found that spirometry restrict…
A normal breathing test might hide a serious lung problem that makes you three times more likely to develop scarring and 45% more likely to …
Nine patients with PPFE and DGUOK-associated mitochondriopathy show specific genetic and cellular findings
Lung Scarring Linked to Rare Gene Defect
This review of nine cases describes patients with pleuroparenchymal fibroelastosis (PPFE) and DGUOK-associated mitochondriopathy.
A rare gene defect causes severe lung scarring in adults and children, explaining why some patients suffer from progressive shortness of bre…