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Pulmonology & Critical Care

211 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
FDA Approves Tyvaso (treprostinil) for Pulmonary Arterial Hypertension and Pulmonary Hypertension Associated with Interstitial Lung Disease
Pulmonology & Critical Care FDA Approval
FDA Approves Tyvaso (treprostinil) for Pulmonary Arterial Hypertension and Pulmonary Hypertension Associated with Interstitial Lung Disease FDA approves new inhaled drug called Tyvaso for two serious lung conditions
The FDA approved Tyvaso (treprostinil) for pulmonary arterial hypertension (PAH; WHO Group 1) and pulmonary hypertension associated with int…
FDA approves new inhaled drug Tyvaso to help adults with serious lung conditions improve their ability to exercise and do daily activities.
Prophylactic rhG-CSF with platinum chemotherapy improves immune markers and response rates in advanced lung cancer patients
Pulmonology & Critical Care RCT
Prophylactic rhG-CSF with platinum chemotherapy improves immune markers and response rates in advanced lung cancer patients New drug boost may help some advanced lung cancer patients respond better to treatment
This randomized controlled trial enrolled 150 patients with advanced lung cancer at a hospital in Yuhang District.
A new drug boost helps advanced lung cancer patients maintain stronger white blood cell counts and fight infections better during standard c…
Mindfulness interventions show mixed effects on breathlessness and pulmonary function in lung cancer patients
Pulmonology & Critical Care Meta-analysis
Mindfulness interventions show mixed effects on breathlessness and pulmonary function in lung cancer patients Mindfulness helps lung function and mood in lung cancer patients, but not breathlessness
A meta-analysis of 14 RCTs involving 1,190 lung cancer patients found mindfulness-based interventions did not significantly improve breathle…
Mindfulness improved lung function and mood for cancer patients, but it did not reduce the feeling of breathlessness.
First-line osimertinib shows high response rates in EGFR-mutated NSCLC with active brain metastases
Pulmonology & Critical Care Phase II
First-line osimertinib shows high response rates in EGFR-mutated NSCLC with active brain metastases Untreated Brain Metastases Respond Well to Osimertinib
This single-arm phase II trial evaluated first-line osimertinib in 100 patients with EGFR-mutated non-small cell lung cancer, including thos…
Osimertinib, a lung cancer drug, effectively treats untreated brain metastases, with an 81.8% response rate for measurable brain spots in a …
Virtual wards and hospital at home show no survival or readmission benefit for ECOPD patients compared to hospital admission
Pulmonology & Critical Care Meta-analysis
Virtual wards and hospital at home show no survival or readmission benefit for ECOPD patients compared to hospital admission Home Hospital Care for COPD Flares Shows No Clear Win
This systematic review and meta-analysis evaluated virtual wards (VW) and hospital at home (HaH) versus hospital admission for adults with e…
Sending COPD patients home with remote monitoring did not reduce deaths or readmissions, but it also did not cause harm.
Non-cirrhotic portal fibrosis identified in 32.6% of pre-cirrhotic primary biliary cholangitis patients in a retrospective analysis
Pulmonology & Critical Care Cohort
Non-cirrhotic portal fibrosis identified in 32.6% of pre-cirrhotic primary biliary cholangitis patients in a retrospective analysis Hidden Liver Damage Found in Early PBC
This retrospective analysis examined 92 biopsy-proven pre-cirrhotic primary biliary cholangitis (PBC) patients to characterize non-cirrhotic…
Many people with primary biliary cholangitis develop hidden liver damage called non-cirrhotic portal fibrosis before permanent scarring begi…
Phase Ib/II trial of nintedanib plus nivolumab in pretreated NSCLC adenocarcinoma shows 25% 6-month PFS rate
Pulmonology & Critical Care Phase I
Phase Ib/II trial of nintedanib plus nivolumab in pretreated NSCLC adenocarcinoma shows 25% 6-month PFS rate New Drug Combo Helps Some Lung Cancer Patients Live Longer
A single-arm, open-label phase Ib/II trial in 52 patients with pretreated stage IIIB/IV NSCLC adenocarcinoma found a 6-month progression-fre…
A new drug pair safely extends life for some advanced lung cancer patients who previously tried immunotherapy or have high PD-L1 markers.
EMG measurement is feasible in primary care for stable mild to moderate COPD patients
Pulmonology & Critical Care RCT
EMG measurement is feasible in primary care for stable mild to moderate COPD patients A Simple Test Can Now Track Your COPD’s Hidden Strain
This randomized controlled trial assessed the feasibility of parasternal electromyography (EMG) in 40 participants with stable mild to moder…
A new, easy-to-use sensor can detect the extra work your breathing muscles are doing because of COPD, giving doctors a clearer picture of yo…
Age-period-cohort analysis shows declining bacteriologically confirmed pulmonary tuberculosis incidence in Hunan Province, China, 2009–2023
Pulmonology & Critical Care Cohort
Age-period-cohort analysis shows declining bacteriologically confirmed pulmonary tuberculosis incidence in Hunan Province, China, 2009–2023 For decades, the fight against tuberculosis (TB) has followed a familiar script. But new data reveals the story is changing. The faces of those most vulnerable are shifting in surprising ways
This review analyzed population-based surveillance data from Hunan Province, China, from 2009 to 2023 to assess trends in bacteriologically …
Tuberculosis risk now peaks in young adults and the elderly, with the sharpest rise in the oldest age group, signaling a shift in who needs …
Meta-analysis finds inhaled corticosteroids associated with reduced cardiovascular mortality in COPD patients
Pulmonology & Critical Care Meta-analysis
Meta-analysis finds inhaled corticosteroids associated with reduced cardiovascular mortality in COPD patients A Common COPD Medicine May Also Protect Your Heart
A systematic review and meta-analysis of 74,004 COPD patients found inhaled corticosteroid-containing formulations were associated with redu…
For people with COPD, a medication they already use to breathe easier might also offer a hidden layer of protection for their heart.
Meta-analysis finds limited evidence for CPET variables in COPD mortality prediction
Pulmonology & Critical Care Meta-analysis
Meta-analysis finds limited evidence for CPET variables in COPD mortality prediction CPET variables linked to COPD mortality but routine use not yet supported
A systematic review and meta-analysis of 16 studies in COPD patients examined cardiopulmonary exercise testing (CPET) variables for predicti…
Peak oxygen uptake and ventilatory efficiency from exercise tests predict death in chronic obstructive pulmonary disease, though routine use…
Monthly phone counseling increased willingness to set lifestyle goals in patients with chronic obstructive pulmonary disease
Pulmonology & Critical Care RCT
Monthly phone counseling increased willingness to set lifestyle goals in patients with chronic obstructive pulmonary disease Most COPD patients willing to set lifestyle goals after counseling
This randomized controlled trial evaluated monthly phone calls offering lifestyle counseling on diet and physical activity using motivationa…
Most COPD patients are willing to set lifestyle goals after counseling, with 71% focusing on physical activity and adjusting targets as need…