Chemoimmunotherapy improves objective response rate and survival in advanced pulmonary large-cell neuroendocrine carcinoma
Combining Chemotherapy and Immune Therapy Improves Outcomes for Advanced Lung Cancer
This meta-analysis of 3537 patients with advanced pulmonary large-cell neuroendocrine carcinoma (LCNEC) found that chemoimmunotherapy signif…
Adding an immune-boosting drug to standard chemotherapy helps patients with a specific type of advanced lung cancer live longer.
Evaluating Bevacizumab Addition to Atezolizumab Carboplatin and Pemetrexed in Nonsquamous NSCLC
Trial shows bevacizumab addition has mixed results for lung cancer
A Phase III trial assessed adding bevacizumab to a standard triplet regimen for advanced nonsquamous NSCLC, showing no significant OS improv…
A Phase 3 trial found that adding bevacizumab to a standard drug combination did not improve overall survival for most patients with advance…
Rapid on-site evaluation achieves 88.1% sensitivity and 91.7% specificity for lung cancer detection
Rapid on-site testing improves lung cancer detection during bronchoscopy
This meta-analysis of diagnostic data evaluates the accuracy of rapid on-site evaluation (ROSE) during endobronchial ultrasound-guided bronc…
A new method of checking samples immediately during a procedure helps doctors more accurately identify lung cancer in specific cases.
Lily polysaccharide may mitigate radiation-induced pneumonitis by modulating the gut-lung axis and pulmonary signaling
Lily Polysaccharide May Help Manage Radiation-Induced Pneumonitis
This systematic review explores the potential of Lily polysaccharide (LP) to treat radiation-induced pneumonitis. The authors synthesize evi…
New research explores how lily polysaccharide might protect the lungs from radiation damage by influencing gut health and reducing inflammat…
Treatable traits protocol aims to reduce exacerbations in AECOPD patients
New trial to test personalized treatment for COPD flare-ups
This protocol describes a planned randomized controlled trial across 6 centers in China enrolling 314 patients with acute exacerbation of CO…
A new trial will test if personalized treatment based on 'treatable traits' can reduce COPD flare-ups and hospitalizations.
Early assessment at 4 weeks versus 8 weeks increases abstinence odds in tobacco users
Early Assessment May Improve Success Rates for Quitting Smoking
This randomized controlled trial of 636 daily smokers eligible for lung cancer screening found that a 4-week assessment interval was associa…
Checking progress at 4 weeks instead of 8 weeks may help people who smoke daily successfully quit using nicotine replacement therapy.
Low-dose N-acetylcysteine reduces acute exacerbation risk in patients with chronic obstructive pulmonary disease
N-acetylcysteine may reduce flare ups for people with COPD
This meta-analysis of randomized controlled trials involving 2,856 patients found that low-dose N-acetylcysteine (≤600 mg/day) significantly…
A specific dose of N-acetylcysteine could help lower the risk of sudden breathing problems for people living with chronic obstructive pulmon…
Polygenic risk scores and air pollutants associated with increased lung cancer risk
Genetic Scores and Air Pollution Linked to Lung Cancer Risk
This randomized controlled trial analyzed a cohort of 7,364 individuals to evaluate the impact of polygenic risk scores (PRS) and ambient ai…
New research shows that genetic risk scores and exposure to air pollutants are linked to higher lung cancer risk in a large screening group.
Health literacy-sensitive self-management programs improve exercise capacity and symptom burden in patients with COPD
Specialized self-management programs improve outcomes for people with COPD
This meta-analysis evaluated the impact of self-management interventions incorporating health literacy-sensitive components on adults with C…
New data shows that self-management programs designed to overcome health literacy barriers can improve walking distance and lung function fo…
Ensartinib improves 24-month disease-free survival to 86.4% in resected ALK-positive NSCLC
New drug shows promise for specific type of lung cancer
This Phase 3 randomized trial of 274 patients with resected, ALK-positive stage IB to IIIB NSCLC found that ensartinib (225 mg once daily) s…
A new medication called ensartinib significantly improved the time patients lived without their lung cancer returning after surgery.
Biologic therapies targeting T2 inflammatory pathways reduce exacerbation rates in COPD patients
Biologic Therapies Reduce Exacerbations in Specific COPD Patients
This meta-analysis evaluated biologic therapies targeting T2 inflammatory pathways in patients with COPD and biomarker-defined T2 inflammati…
New research shows that biologic therapies targeting specific inflammatory pathways can reduce severe flare-ups for patients with certain ty…
Organizational resilience and psychological support are key to improving ICU nurse teamwork during pandemics
Teamwork challenges and strengths for ICU nurses in COVID-19
This meta-synthesis of 48 qualitative studies examines the challenges and coping strategies of ICU nurses regarding team collaboration durin…
A review of 48 studies reveals what helped and hurt teamwork for ICU nurses during COVID-19.