COPD caregiver health literacy is low, assessment tools lacking, scoping review finds
Caregivers of COPD patients often have low health literacy
A scoping review of 7 studies found that health literacy among COPD caregivers is relatively low, influenced by sociodemographic, caregiving…
Many people caring for loved ones with chronic lung disease struggle to understand medical information and lack specialized support tools.
Elevated nocturnal respiratory rate is associated with increased odds of diabetes mellitus in large cohorts
Higher Nocturnal Respiratory Rates Linked to Increased Diabetes Risk
This meta-analysis of four observational cohorts involving over 25,000 individuals found that higher nocturnal respiratory rates (NRR) are a…
A large analysis shows that people with higher breathing rates at night have a higher likelihood of having diabetes.
Vitamin D deficiency increases odds of sepsis and mechanical ventilation in neonates
Vitamin D Deficiency Linked to Higher Sepsis Risk in Neonates
This meta-analysis of 18 studies involving 1981 patients found that Vitamin D deficiency is associated with a higher risk of sepsis and incr…
Low vitamin D levels are linked to higher rates of sepsis and longer hospital stays for babies in neonatal intensive care units.
FDA Approves Provocholine (methacholine chloride) for Bronchial Airway Hyperreactivity Diagnosis
FDA approves new test to help diagnose asthma in certain patients
The FDA approved Provocholine (methacholine chloride) for diagnosing bronchial airway hyperreactivity in adults and children aged 5 years an…
The FDA approved Provocholine, a drug used in a breathing test to diagnose airway hyperreactivity in people aged 5 and older who may have as…
Tislelizumab plus chemotherapy improves survival in extensive-stage small cell lung cancer
Immunotherapy combo extends survival in small cell lung cancer
This phase 3 RCT evaluated tislelizumab plus chemotherapy versus placebo plus chemotherapy in previously untreated extensive-stage small cel…
Adding tislelizumab to chemo helped people with extensive-stage small cell lung cancer live 2 months longer, a phase 3 trial shows.
Lower PEEP may increase ventilator-free days in ventilated patients without ARDS
Lower breathing pressure settings showed modest benefits for some critically ill patients without lung injury
This Bayesian re-analysis of an RCT in 980 invasively ventilated critically ill patients without ARDS found that lower PEEP (0-5 cm H2O) com…
A re-analysis of data found that using the lowest safe breathing pressure might help some patients breathe easier. However, the overall bene…
Machine learning models show moderate accuracy predicting neoadjuvant immunotherapy response in NSCLC
Machine learning models predict how well lung cancer patients respond to immunotherapy
This systematic review and meta-analysis of 44 models found that machine learning predicts neoadjuvant immunotherapy response in resectable …
A new analysis of 44 models shows computer programs can guess which lung cancer patients will benefit from immunotherapy, though the study h…
1 in 7 COPD patients decline or discontinue long-term PAP therapy, meta-analysis finds
1 in 7 COPD patients decline or stop breathing therapy
This systematic review and meta-analysis of patients with COPD newly prescribed long-term noninvasive positive airway pressure (PAP) therapy…
A new analysis finds 14% of COPD patients decline or stop long-term breathing therapy, often within six weeks.
COPD patients show heightened sympathetic nerve activity compared to healthy adults
COPD patients have much higher nerve activity than healthy adults
A meta-analysis finds COPD patients have significantly higher sympathetic nerve activity than controls, with no change from common therapies…
People with COPD show significantly higher sympathetic nerve activity compared to healthy adults, which may explain their heart and exercise…
Meta-analysis links baseline and dynamic ctDNA to survival in advanced NSCLC
ctDNA in blood predicts survival in advanced lung cancer
This systematic review and meta-analysis of 43 studies found that detectable or elevated baseline plasma ctDNA was associated with worse ove…
A blood test for tumor DNA can predict survival in advanced lung cancer, helping guide treatment decisions.
Pirfenidone reduces lung cancer incidence by 73% in IPF patients with a pooled risk ratio of 0.39
Antifibrotic drugs may lower lung cancer risk in patients with idiopathic pulmonary fibrosis
This systematic review and meta-analysis evaluated antifibrotic therapies in 15582 patients with idiopathic pulmonary fibrosis. The pooled a…
A large review suggests antifibrotic drugs like pirfenidone might lower lung cancer risk in people with idiopathic pulmonary fibrosis, but m…
Immune checkpoint inhibitors before lung cancer surgery show acceptable safety profile
Immunotherapy before lung cancer surgery is safe, study finds
This meta-analysis of patients with resectable non-small cell lung cancer found that neoadjuvant or perioperative immune checkpoint inhibito…
A new analysis of 2,691 patients shows that immunotherapy before lung cancer surgery is feasible, but comes with specific surgical challenge…