N/A
N=110
Home-Based Exercise and Weight Control Program for Pain Control in Overweight Elderly With Osteoarthritis of the Knee
Chronic Diseases · Obesity · Osteoarthritis · Pain
Bottom Line
View on ClinicalTrials.gov: NCT00126737 ↗Enrolled (actual)
110
Serious AEs
0.0%
Results posted
Jan 2015
Primary outcome: Primary: WOMAC Function — -10.4; -4.8; -4.9; -1.6 Change in Score — p=0.0129
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Weight Control Nutritional Program (Other); Home-based exercise program (Other)
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- US Department of Veterans Affairs
- Primary completion
- Feb 2008
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY WOMAC Function |
-10.4; -4.8; -4.9; -1.6 | 0.0129 sig |
| PRIMARY Physical Scale SF-36v |
5.51; 0.56; 3.58; 0.34 | 0.0307 sig |
| PRIMARY Mental Scale SF-36v |
0.28; 2.62; -0.23; -2.64 | — |
| SECONDARY Walking Distance |
71.64; 17.42; 42.08; 6.55 | 0.0158 sig |
| SECONDARY Stair Total (Climb, Descend) |
39.75; 23.61; 40.48; 9.06 | 0.0018 sig |
Summary
The purpose of this study is to determine whether a home-based exercise and weight control program applied to elderly overweight individuals with painful osteoarthritis of the knee, would result in pain reduction.
Eligibility Criteria
Inclusion Criteria
- Male & female 50 years old
- Diagnosis of osteoarthritis by American College of Rheumatology criteria
- Knee radiographs of Kellgren and Lawrence grade 2-4
- American Arthritis Association functional class 1-3
- Body mass index of 27
Exclusion Criteria
- Knee arthritis which did not meet American College of Rheumatology (ACR) OA criteria
- Unable to engage in exercise or follow instruction
- Limited shoulder range of motion
Data sourced from ClinicalTrials.gov (NCT00126737). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.