N/A
Completed N=79
Functional Rehabilitation of Older Patients With Schizophrenia
Source: ClinicalTrials.gov NCT00237796 ↗Enrolled (actual)
79
Serious AEs
19.0%
Results posted
Apr 2015
Primary outcomePrimary: Independent Living Skills Survey (ILSS) — 0.66; 0.70; 0.68; 0.71 units on a scale
Summary
The primary purpose of this project is to evaluate the efficacy of a group therapy intervention, cognitive behavioral social skills training (CBSST), that teaches social functioning skills and cognitive-behavioral compensatory aids to older patients with schizophrenia. CBSST, therefore, targets the multidimensional deficits that lead to disability in aging veterans with severe mental illness.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Independent Living Skills Survey (ILSS) |
0.66; 0.70; 0.68; 0.71; 0.68; 0.71 | — |
| SECONDARY Comprehensive Module Test (CMT) |
6.2; 4.8; 8.6; 6.2; 12.0; 5.5 | — |
| SECONDARY Positive and Negative Syndrome Scale (PANSS) - Positive Subscale |
18.3; 17.8; 17.4; 15.5; 15.5; 16.1 | — |
| SECONDARY Scale for the Assessment of Negative Symptoms (SANS) - Diminished Expression |
1.63; 1.79; 1.72; 1.48; 1.21; 1.38 | — |
| SECONDARY The Scale for the Assessment of Negative Symptoms (SANS) - Diminished Motivation |
2.02; 2.46; 2.09; 2.15; 1.90; 1.83 | — |
| SECONDARY Beck Depression Inventory-II (BDI-II) |
16.3; 16.4; 17.2; 13.8; 15.0; 14.3 | — |
| SECONDARY Beck Anxiety Inventory (BAI) |
16.4; 14.5; 14.2; 12.4; 15.7; 10.6 | — |
Eligibility Criteria
Inclusion Criteria
- 45 years of age and older
- DSM-IV diagnosis of Schizophrenia or Schizoaffective Disorder
- Fluent in speaking, reading, and writing English
- Physically and psychiatrically stable enough to undergo various assessments in this study
Exclusion Criteria
Has not received Cognitive Behavioral Therapy (CBT) or Social Skills Training (SST) or Dialectical Behavioral Therapy (DBT) in the past 5 years
Data sourced from ClinicalTrials.gov (NCT00237796). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.