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N/A N=79 Randomized Single-blind Treatment

Functional Rehabilitation of Older Patients With Schizophrenia

Psychotic Disorders · Schizoaffective Disorder · Schizophrenia

Enrolled (actual)
79
Serious AEs
19.0%
Results posted
Apr 2015
Primary outcome: Primary: Independent Living Skills Survey (ILSS) — 0.66; 0.70; 0.68; 0.71 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Cognitive Behavioral Social Skills Training (CBSST) (Behavioral); Goal Focused Supportive Contact (GFSC) (Behavioral)
Age
Adult, Older Adult · 45+ yrs
Sex
All
Sponsor
US Department of Veterans Affairs
Primary completion
Jan 2009

Outcome Measures

OutcomeResultp-value
PRIMARY
Independent Living Skills Survey (ILSS)
0.66; 0.70; 0.68; 0.71; 0.68; 0.71
SECONDARY
Comprehensive Module Test (CMT)
6.2; 4.8; 8.6; 6.2; 12.0; 5.5
SECONDARY
Positive and Negative Syndrome Scale (PANSS) - Positive Subscale
18.3; 17.8; 17.4; 15.5; 15.5; 16.1
SECONDARY
Scale for the Assessment of Negative Symptoms (SANS) - Diminished Expression
1.63; 1.79; 1.72; 1.48; 1.21; 1.38
SECONDARY
The Scale for the Assessment of Negative Symptoms (SANS) - Diminished Motivation
2.02; 2.46; 2.09; 2.15; 1.90; 1.83
SECONDARY
Beck Depression Inventory-II (BDI-II)
16.3; 16.4; 17.2; 13.8; 15.0; 14.3
SECONDARY
Beck Anxiety Inventory (BAI)
16.4; 14.5; 14.2; 12.4; 15.7; 10.6

Summary

The primary purpose of this project is to evaluate the efficacy of a group therapy intervention, cognitive behavioral social skills training (CBSST), that teaches social functioning skills and cognitive-behavioral compensatory aids to older patients with schizophrenia. CBSST, therefore, targets the multidimensional deficits that lead to disability in aging veterans with severe mental illness.

Eligibility Criteria

Inclusion Criteria

  • 45 years of age and older
  • DSM-IV diagnosis of Schizophrenia or Schizoaffective Disorder
  • Fluent in speaking, reading, and writing English
  • Physically and psychiatrically stable enough to undergo various assessments in this study

Exclusion Criteria

Has not received Cognitive Behavioral Therapy (CBT) or Social Skills Training (SST) or Dialectical Behavioral Therapy (DBT) in the past 5 years

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00237796). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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