Phase 2
Completed N=21
Effect of Growth Hormone on Bone Metabolism in Anorexia Nervosa
Source: ClinicalTrials.gov NCT00283595 ↗Enrolled (actual)
21
Serious AEs
0.0%
Results posted
Oct 2012
Primary outcomePrimary: Bone Metabolism — 34.3; 10.4 ng/ml
Summary
Decreased bone strength is a serious medical problem present in many women with Anorexia Nervosa, or disordered eating. Women with weaker bones are more likely to suffer broken bones than women with normal bone strength.
We are investigating whether a hormone that is naturally produced by the human body, called growth hormone, can help strengthen the bones of women with this type of disordered eating.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Bone Metabolism |
34.3; 10.4 | — |
| SECONDARY IGF-1 Level |
6.5; 10 | — |
Eligibility Criteria
Inclusion Criteria
- women between 14 to 45 years with anorexia nervosa
Exclusion Criteria
- pregnancy
- previous history of malignancy.
- oral contraceptive pills or other hormones within last 8 - 12 weeks
- medications known to affect bone within last 12 weeks
- fracture within last 6 months
Data sourced from ClinicalTrials.gov (NCT00283595). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.