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Eating disorders

6 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for eating disorders

27 trials tracked for eating disorders: 5 in phase 3 or 4 and 1 with published results. The most-cited published study has 392 citations.

27Trials tracked
5Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 3 Phase 3 2 Phase 2 4 Phase 1 2 Other / NA 16
  1. Phase 4 Fluoxetine to Prevent Relapse and Enhance Psychological Recovery in Women With Anorexia Nervosa Completed · 392 cited
  2. Phase 4 Monoamine Contributions to Neurocircuitry in Eating Disorders Completed
  3. Phase 4 Effectiveness of Atypical Antipsychotic Medication for Outpatients With Anorexia Nervosa Completed
  4. Phase 3 Effects of Denosumab on Bone Mineral Density in Women With Anorexia Nervosa: A Pilot Study Completed
  5. Phase 3 Effects of Romosozumab on Bone Density in Women With Anorexia Nervosa Completed
  6. Phase 2 Effectiveness of Olanzapine Versus Placebo in Treating Outpatients With Anorexia Nervosa Completed
Show 21 more trials
  1. Phase 2 Hormonal Factors in the Treatment of Anorexia Nervosa Completed
  2. Phase 2 Effect of Growth Hormone on Bone Metabolism in Anorexia Nervosa Completed
  3. Phase 2 Effectiveness of Antibiotic Treatment for Reducing Binge Eating and Improving Digestive Function in Bulimia Nervosa Completed
  4. Phase 1 Leveraging Social Media to Identify and Connect Teens With Eating Disorders to a Mobile Guided Self-Help Mobile Intervention Completed
  5. Phase 1 Naltrexone Neuroimaging Completed
  6. N/A Treatment Uptake Chatbot for Eating Disorders Completed
  7. N/A An fMRI Study of Self-regulation in Adolescents With Bulimia Nervosa Completed
  8. N/A Comparing the Effectiveness of Two Therapies to Treat Signs of Anorexia Nervosa in Adolescents Completed
  9. N/A Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations Completed
  10. N/A Efficacy Trial of a Dissonance Based Eating Disorder Program Completed
  11. N/A Eating Disorder Prevention Program for Women With T1D Completed
  12. N/A Adding Guided Self-Help Group Therapy to the Alli Weight Loss Program in Treating Binge Eating Disorder Completed
  13. N/A The Body Project: Comparing the Effectiveness of an In-person and Virtually Delivered Intervention. Completed
  14. N/A Multi-Family Group Therapy for Adult Eating Disorders Completed
  15. N/A Evaluation of the Communities of Healing Mentorship/Support Group Program: Assessment of Preliminary Efficacy Completed
  16. N/A Improving Weight Loss Outcomes for Binge Eating Disorder. Completed
  17. N/A Neuromodulation Enhanced Cognitive Restructuring: A Proof of Concept Study Completed
  18. N/A MUMMIBODIES. Eating Disorders, Pregnancy and Post Partum Period. Completed
  19. N/A Efficacy of the Female Athlete Body Project (FAB) Completed
  20. N/A Motivate: A Web-based Intervention Completed
  21. N/A Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health Completed

Showing the 27 most-cited and recently-updated of 27 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Eating disorders: what the trials found

Pharmacological interventions show varying results for specific conditions and symptoms. Fluoxetine was associated with a statistically significant reduction in psychological symptoms as measured by the Beck Anxiety Inventory (BAI) over treatment periods 2. Olanzapine was evaluated in multiple trials, including one specifically focused on its administration 10, though specific outcome metrics for these studies were not detailed beyond the intervention itself.

In bone health research, Romosozumab demonstrated a significant increase in postero-anterior lumbar spine bone mineral density at 12 months compared to the control group 5. Denosumab also showed statistically significant results in postero-anterior lumbar spine bone mineral density measurements 6, although its specific percentage change from baseline did not reach statistical significance.

Neuroimaging studies using [11C]raclopride identified significant differences in Dopamine D2/D3 receptor binding after amphetamine administration 3. Additionally, a study on weight management showed that Olanzapine was associated with a change in weight at 12 weeks compared to the control group 4.

Recent results — preliminary, needs further review

  • The 'Space From Body and Eating Concerns- Teen' intervention did not show statistically significant differences in eating disorder psychopathology, quality of life scores, or total time spent on the app 1.
  • Peer mentorship was associated with a significant reduction in binge days and lower body dissatisfaction scores on the EPSI scale 21.
  • Cognitive restructuring was associated with improved physiological emotion regulation and faster times to return to heart rate baseline during training periods 22.

For the clinician treating this condition

  • Fluoxetine is associated with significant improvements in anxiety symptoms (BAI) in relevant patient populations 2.
  • Romosozumab shows a statistically significant positive impact on lumbar spine bone mineral density at 12 months 5.
  • Cognitive restructuring and peer mentorship have shown statistically significant improvements in emotional regulation and eating disorder-specific symptoms, respectively [21, 22].

AI synthesis of 9 cited trials, updated Jun 29, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Questions about eating disorders

Do GLP-1 agents address eating disorders through appetite and gut-brain signaling pathways?

GLP-1 agents address eating disorders by targeting appetite and gut-brain signaling pathways that regulate food reward and intake.

Full answer →