N/A Completed N=4,005 Randomized Single-blind Screening

Indiana University Dementia Screening Trial

Dementia · Alzheimer's Disease · Mild Cognitive Impairment

Source: ClinicalTrials.gov NCT01699503 ↗

Enrolled (actual)

4,005

Serious AEs

2.9%

Results posted

Jan 2019

Primary outcomePrimary: Health Related Quality of Life (HRQOL) — 0.71; 0.69; 0.69; 0.70 units on a scale

Summary

The purpose of the study is to conduct a randomized clinical trial assessing the harms and benefits of screening for dementia, compared to no screening for dementia, among 4,000 older adults, cared for in typical, primary care practices.

Outcome Measures

Outcome	Result	p-value
PRIMARY Health Related Quality of Life (HRQOL)	0.71; 0.69; 0.69; 0.70; 0.67; 0.68	—
PRIMARY Patient Health Questionnaire (PHQ-9)	2.33; 2.46; 2.50; 2.45; 2.74; 2.82	—
PRIMARY Generalized Anxiety Disorder Scale (GAD-7)	1.16; 1.24; 1.24; 1.13; 1.31; 1.45	—
SECONDARY Number of Participants With Health Care Utilization	510; 512; 336; 333	—
SECONDARY Number of Participants With an Advance Directive at 12 Months	653; 644	—

Eligibility Criteria

Inclusion Criteria

adults age 65 and older;
at least one office visit to their primary care physician within the previous year;
no previous diagnosis of dementia or memory problem as determined by ICD-9 codes or the presence of prescription for anti-dementia medications (cholinesterase inhibitors or memantine);
ability to consent to participate in the study; and
ability to communicate in English

Exclusion Criteria

adults who are a permanent resident of a nursing facility;
a serious mental illness such as bipolar disorder or schizophrenia as determined by the presence of related ICD-9 codes indicative of such an illness; or
a pre-existing diagnosis of dementia or cognitive impairment

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01699503). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.