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Phase 2 Completed N=24 Randomized Quadruple-blind Treatment

Treatment of Anxiety and Anorexia Nervosa in Adolescents

Source: ClinicalTrials.gov NCT01933243 ↗
Enrolled (actual)
24
Serious AEs
0.0%
Results posted
Apr 2018
Primary outcomePrimary: Medication Side Effects Score — 9.5; 6.2; 6.4; 4.1 Score on a scale

Summary

Adolescents with anorexia nervosa frequently have associated anxiety, and standard medications used for anxiety are unhelpful when patients are malnourished. This is a 12 week trial examining the safety, tolerability, and effectiveness of fish oil nutritional supplements for anxiety in adolescents with anorexia nervosa.

Outcome Measures

OutcomeResultp-value
PRIMARY
Medication Side Effects Score
9.5; 6.2; 6.4; 4.1
SECONDARY
Beck Anxiety Inventory-Trait (BAIT)
26.4; 19.3; 21.9; 11; 14.9; 6.5

Eligibility Criteria

Inclusion Criteria

Females admitted to Nationwide Children's Hospital Eating Disorder Partial Hospitalization Program

Exclusion Criteria

  • Inability to take pills
  • Co-morbid medical conditions affecting appetite and weight (e.g., inflammatory bowel disease, cancer, cystic fibrosis)
  • Co-morbid psychiatric conditions affecting appetite and weight (e.g., bipolar disorder, substance abuse)
  • Currently taking fish oil supplements
  • Inability to participate in study for 12 consecutive weeks.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01933243). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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