Phase 4 N=60 Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. Anxiety
Anxiety Disorder
Primary: Magnitude of Startle Reflex During Safe Condition — 42.2880893; 42.39801; 43.61243; 44.1886408 millivolts (mV)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=59 A Single-Session Intervention for Families on Waitlists for Child Anxiety Treatment
Anxiety Disorders
Primary: Screen for Child Anxiety Related Emotional Disorders - Parent Version at Posttreatment — 35; 30 units on a scale
N/A N=918 Expectation of Unpleasant Events in Anxiety Disorders
Anxiety Disorders
Primary: Change in Percent of Correct Button Presses During Threat Compared to the Safe Condition (AAST) — -0.016; 0.008 Percentage of accurate responses
Phase 2 N=70 Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism in Anxious Alcoholics^
Alcohol-Related Disorders · Alcohol Dependence · Alcoholism
Primary: Alcohol Craving in Response to the Alcohol Cue Script — 12.7; 10.7 Units on a scale
N/A N=63 Digital Intervention to Treat Anxiety and Depression Among Persons Receiving Treatment for Opioid Use Disorder
Opioid-use Disorder · Anxiety Disorders · Depressive Disorder
Primary: Change in Anxiety Symptoms as Assessed by Generalized Anxiety Disorder- Q-IV Scale — -1.8; -1.04; -2.47; -1.53 units on a scale — p=.755
N/A N=64 Early Intervention for Children at Risk for Anxiety
Anxiety Disorder
Primary: Number of Responders Based on Clinician Global Impression-Anxiety Improvement — 20; 9 Participants — p=<.05
N/A N=89 Comparing Virtual Reality (VR) to Non-VR for Decreasing Preoperative/Procedural Anxiety
Preoperative Anxiety
Primary: Preoperative Anxiety Score in Pediatric Oncology Patients — 31.44; 28.26; 45.38; 32.81 score on a scale
N/A N=193 Pain Monitoring After Breast Biopsy: Benefit of E-health
Breast Cancer · Biopsy Wound
Primary: Number of Participants by Pain Intensity at Day 4 Post Breast Biopsy With a Benefit of Intervention by E-health (Phone Consultation With a Professional or Connected…
N/A N=93 The Effect of Vibration and Cold on Pain and Anxiety Associated With Chest Tube Removal Following CABG
Pain, Procedural · Pain, Postoperative · Coronary Artery Bypass Surgery
Primary: Mediastinal Chest Tube Pain — 1.38; 1.76; 1.43; 0.21 score on a scale
Phase 4 N=79 Intranasal Midazolam for Treatment of Anxiety in Children Undergoing Suturing in the Pediatric Emergency Department
Anxiety · Lacerations
Primary: Intention to Treat (ITT): Modified Yale Preoperative Anxiety Score (mYPAS) — 59.9201; 46.2871 units on a scale — p=0.026
N/A N=114 Relationship Between Preoperative Anxiety, Postoperative Pain, and Emergence Delirium in Pediatric Surgery
Postoperative Pain · Preoperative Anxiety · Emergence Delirium in Pediatric Anesthesia
Primary: Postoperative Pain Intensity — 1; 1; 3; 1 score
N/A N=117 Cartoon Distraction and Parental Presence on Anxiety in Pediatric Anesthesia
Anxiety, Separation · Psychomotor Agitation
Primary: Modified Yale Preoperative Anxiety Scale Scores at Baseline, Arrival in Operating Room, and Inhalation Induction — 28.4; 28.4; 23.4; 23.4 units on a scale
N/A N=1,419 Brief Digital Intervention to Increase COVID-19 Vaccination Among Individuals With Anxiety or Depression
Misinformation · Vaccine Hesitancy · Anxiety
Primary: Self-reported Receipt of COVID Vaccine Dose by 4 Weeks Post-intervention — 4; 7; 6; 462 Participants
N/A N=4,001 Chronic Obstructive Pulmonary Disease (COPD)-Related Outcomes and Costs for Patients on Combination Fluticasone Propionate-Salmeterol Xinafoate 250/50mcg Versus Anticholinergics in a COPD-Comorbid Depression/Anxiety Population
Pulmonary Disease, Chronic Obstructive
Primary: Number of Participants With Any Chronic Obstructive Pulmonary Disease (COPD)-Related Exacerbation — 200; 674 participants — p=0.002
N/A N=75 Assessing Mechanisms of Anxiety Reduction in Animal-assisted Interventions
Social Anxiety Disorder · Social Anxiety · Social Anxiety Disorder of Childhood
Primary: Self-reported Affective Experience — 10.19; 10.00; 10.28; 8.33 units on a scale — p=.723