N/A
N=43
Neural Changes Associated With a Mindfulness-based Intervention for Young Adults With Childhood Maltreatment
Depression · Anxiety · PTSD · Trauma, Psychological
Bottom Line
View on ClinicalTrials.gov: NCT02447744 ↗Enrolled (actual)
43
Serious AEs
0.0%
Results posted
Mar 2021
Primary outcome: Primary: Changes in Subjects' Perceived Stress Level — -5.526; 1.000 score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Mindfulness based intervention (Behavioral)
- Age
- Adult · 19+ yrs
- Sex
- All
- Sponsor
- Massachusetts General Hospital
- Primary completion
- Jul 2016
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Changes in Subjects' Perceived Stress Level |
-5.526; 1.000 | — |
| SECONDARY Changes of Mindfulness |
0.337; 0.049 | — |
Summary
Childhood trauma is remarkably prevalent, and it has long lasting impact on mental health and neural development. This trial aims to see whether the 8-week mindfulness based intervention can reduce stress related psychological symptoms for young adults with childhood maltreatment, and whether it can promote neural plasticity.
Eligibility Criteria
Inclusion Criteria
- Experience of childhood maltreatment
- With current age between 19 to 35 years old
- With current symptoms of depression or anxiety or PTSD or significant general stress.
Exclusion Criteria
- History of psychiatric disorders with psychotic features
- Suicidal attempts during the past six months
- Neurological disorders
- And common MRI exclusion criteria
- Prior history with the mindfulness based stress reduction program or other systematic meditation programs.
Data sourced from ClinicalTrials.gov (NCT02447744). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.