Minnesota Community-Based Cognitive Training in Early Psychosis

Inclusion Criteria

• Clinical diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder, major depressive disorder with psychotic features, bipolar disorder with psychotic features, psychosis disorder not otherwise specified, or unspecified schizophrenia spectrum disorder, and started receiving treatment services at a First Episode Psychosis Program within the last two years
• Good general physical health
• Aged between 16 and 35 years (inclusive)
• Fluent in spoken and written English
• No neurological disorder (diagnosis of Autism Spectrum Disorder is allowed)
• Achieved clinical stability, defined as outpatient status for at least one month prior to study participation, stable doses of psychiatric medications for at least one month prior to study participation
• Women who are pregnant or breastfeeding may participate in this study.

Exclusion Criteria

• Unable to provide informed consent
• Participated in significant cognitive training programs within the last three years
• Clinically significant substance abuse that is impeding the subject's ability to participate fully during recruitment, assessment, or training (is unable to remain sober for assessments and training).
• Prescribed >0.5mg daily benztropine (Congentin), >25mg daily diphenhydramine, or high doses of clozapine (>500 mg po qd) or olanzapine (to be determined on a case by case basis).
• Active suicidal ideation at screening or baseline, or previous intent to act on suicidal ideation with a specific plan, preparatory acts, or an actual suicide attempt within the last 6 months, as indicated by the C-SSRS