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N/A N=29 Randomized Treatment

Engaging Black Youth in Depression and Suicide Prevention Treatment Within Urban Schools

Depression · Suicidal Ideation

Enrolled (actual)
29
Serious AEs
0.0%
Results posted
Sep 2025
Primary outcome: Primary: Center for Epidemiological Studies-Depression Scale — 36.84; 40.90 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Making Connections Intervention (Behavioral); IPT-A (Behavioral)
Age
Pediatric, Adult · 12+ yrs
Sex
All
Sponsor
New York University
Primary completion
Dec 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Center for Epidemiological Studies-Depression Scale
36.84; 40.90
PRIMARY
Hamilton Rating Scale for Depression
14.47; 16.60
PRIMARY
Demographic Form
17; 9; 2; 1; 13; 10
PRIMARY
Columbia-Suicide Severity Rating Scale
0.94; 1.1
PRIMARY
Barriers for Adolescents Seeking Health
62.52; 66.5
PRIMARY
Child Help-Seeking Scale
38.68; 39.6; 16.78; 16.44
PRIMARY
Attitudes Toward Psychological Help Scale
6.21; 6.8
PRIMARY
Stages of Change
9.78; 9.8; 13.05; 13.5; 15.26; 14.5
PRIMARY
Barriers to Treatment Participation Scale
64.6; 54.14; 35.06; 27.28; 16.46; 13.42
PRIMARY
Understanding Mood Disorders Questionnaire
18.73; 17
PRIMARY
Therapy Survey
14.8; 12.14
PRIMARY
Suicidal Ideation Questionnaire-Junior
25.68; 29.3
PRIMARY
Global Assessment Scale for Children
57.84; 53.7
PRIMARY
Interpersonal Needs
51.26; 61.5
PRIMARY
Penn Helping Alliance Revised
30.87; 29.2

Summary

Completing evidence-based treatments for depression has been shown to be particularly problematic for Black adolescents. If Black adolescents' depression treatment needs are to be met, the engagement challenges and the factors that lessen the success of treatment in the "real world" must be addressed. The investigators will examine the effectiveness of the Making Connections Intervention (MCI) and investigate key mediators of both engagement and response to treatment for depression. The MCI is a 1-2 session, evidence-based intervention designed to improve engagement, perceived relevance, and treatment satisfaction among depressed, Black adolescents. The study also uses tailored outreach strategies for adolescents and parents by including innovative digital content such as a web page/app along with other digital products. This study will address an important public health issue: How best to connect Black adolescents with depression to treatment in clinically meaningful ways, and how best to deliver evidence-based treatment to them through school-based services.

Eligibility Criteria

Inclusion Criteria

  • Must identify as Black and/or African American
  • Must be enrolled in grades 6-12 (except 12th graders in their last semester)
  • Must be able to speak English
  • Must have received caregiver consent and have assented to participate
  • Must meet depression and global functioning levels indicated by a CES-D score ≥16, a Hamilton Rating Scale of Depression (HRSD) Score ≥ 10, and a Global Assessment Scale for Children (C-GAS) score ≤ 65 at baseline
  • Students who are currently on a stable dose of anti-depressant medication, but still meet inclusion criteria, can be enrolled in the study.

Exclusion Criteria

  • Actively suicidal with intent or plan
  • Intellectually disabled
  • Have a life threatening medical illness
  • Have a current primary substance abuse diagnosis in the moderate to severe range, schizophrenia, bipolar disorder, any evidence of psychosis, a primary diagnosis of anorexia
  • Currently in active treatment for depression (excluding medication) at baseline assessment
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03940508). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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