Phase 4 N=84 Does Rosuvastatin Delay Progression of Atherosclerosis in HIV
HIV · Cardiovascular Disease
Primary: Progression of Carotid Intima Media Thickness — 0.0062; 0.004 mm — p=0.684
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=60 Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac Surgery
Delirium
Primary: The Incidence of Delirium (Number of Patients (in Digits)) — 1; 2 participants
Phase 4 N=58 Minocycline Pharmacokinetics (ACUMIN)
Bacterial Infection
Primary: Calculated Exposure Measures for Area Under the Curve 0 to 24 Hours After a Dose (AUC0-24) — 24.3 mg·hr/L
Phase 4 N=15 Immunologic Response to Secukinumab in Plaque Psoriasis
Psoriasis
Primary: Change in Percentage of CD4+ T Effector Cells Expressing IL17 Compared to Baseline — -1.42 percent change from week 0
Phase 4 N=20 The Effect of Enstilar Versus Vehicle on Target Lesions in Moderate Plaque Type Psoriasis Patients
Plaque Psoriasis
Primary: Change in Physicians Global Assessment (PGA) From Baseline to Week 2 and Week 4 — 20; 0; 0; 0 Participants
Phase 4 N=60 Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?
Knee Osteoarthritis · Knee Rheumatism
Primary: Morphine Equivalence Consumption — 12.6; 18.85 MME
Phase 4 N=11 Long-Duration Stimulant Treatment Study of ADHD in Young Children
Attention Deficit Disorder With Hyperactivity
Primary: Swanson, Nolan, and Pelham Questionnaire (SNAP-IV) — -1.09 score on a scale — p=0.01
Phase 4 N=130 Vorapaxar in Patients With Prior Myocardial Infarction Treated With Prasugrel and Ticagrelor
Myocardial Infarction
Primary: Maximal Platelet Aggregation — 52; 64; 74 percent aggregation — p=0.011
Phase 4 N=10 Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage
Cervical Incompetence
Primary: Duration of Motor Block — 75; 99 minutes
Phase 4 N=14 Studying the Effects of Antihypertensives on Individuals at Risk for Alzheimer's
Alzheimer's Disease · Hypertension
Primary: Change in Cerebrospinal Fluid (CSF) Amyloid Beta-42 (Aβ42) Levels Between Baseline and Month 4 in Subjects Taking Ramipril vs Subjects on Placebo — -22.5; -31.71 pg/ml…
Phase 4 N=50 Comparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture Headache
Headache
Primary: Number of Patients (in Digits) Got Earlier Relief of PDPH (in Hours) After Use of Hydrocortisone or Mannitol. — 25; 25 Participants
Phase 4 N=40 Recovery Profile Comparison Between Remifentanil-propofol or Desflurane Anesthesia Monitored With Bispectral Index.
Delayed Emergence From Anesthesia
Primary: Extubation Time — 9.5; 6.2 minutes
Phase 4 N=47 Metformin and Its Impact on the Substances Associated With NO Production in Prediabetes Patients.
PreDiabetes · Impaired Fasting Glucose (IFG) · Impaired Glucose Tolerance (IGT)
Primary: Serum Levels of Metformin at Different Time Points — 4.36; 4.25; 5.09; 7.42 µM
Phase 4 N=310 Effects of Bupivacaine Induced Motor Blockade During the Second Stage of Labor
Pregnancy
Primary: The Duration of the Second Stage of Labor — 75; 73 minutes — p=0.17
Phase 4 N=10 Renal Transplants in Hepatitis C Negative Recipients With Nucleic Acid Positive Donors
End Stage Renal Disease · Hepatitis C
Primary: Viral Response at Week 12 — 10 Participants