12,372 trials
Epilepsy
Primary: Percentage of Participants With Treatment-emergent Adverse Events (TEAEs) During the Study — 94.4; 93.3; 93.6; 92.3 percentage of participants
Cholestasis of Parenteral Nutrition
Primary: Number of Participants With Cholestasis — 1; 3; 7 Participants — p=0.590
Myasthenia Gravis · Myasthenia Gravis, Juvenile Form · Myasthenia Gravis, Generalized
Primary: Change From Baseline in the QMG Total Score at Week 26 Regardless of Rescue Treatment — -6.1 units on a scale — p=0.0004
Asthma
Primary: Area Under the Serial Forced Expiratory Volume in 1 Second (FEV1) — 4.4453; 4.2790; 1.6876 l * hr
Neuromyelitis Optica · Neuromyelitis Optica Spectrum Disorder
Primary: Number of Participants With Treatment Emergent Adverse Events and Serious Adverse Events — 41; 70; 14; 26 Participants
Painful Diabetic Neuropathy · Diabetic Neuropathy, Painful
Primary: Change in the Average 24 Hour Pain Score From Baseline to Day 90 — -1.80; -1.57 units on a scale
Rheumatoid Arthritis
Primary: Maximum Observed Serum Concentration (Cmax) of Adalimumab — 9.156; 8.974 Micrograms per milliliter
HIV Infection
Primary: Percentage of Participants With Human Immunodeficiency Virus 1 Ribonucleic Acid (HIV-1 RNA) ≥50 Copies/mL at Week 48 — 0.6; 0.3; 5.6; 5.3 Percentage of Participants…
Squamous Cell Carcinoma of the Oral Cavity · Squamous Cell Carcinoma of the Soft Palate
Primary: Overall Survival (OS) — 46.3; 58.1; 52.9 months — p=0.4051
Episodic Migraine
Primary: Overall Mean Change From Baseline in the Number of Monthly Migraine Headache Days (MHDs) During the Double-blind Treatment Phase. — -1.99; -3.81 days per month — p=<.0001
Hip Disease
Primary: Numerical Pain Rating System (NRS) Pain Scores — 3.3; 4.4; 4.5; 4.7 score on a scale
Infant, Newborn · Infant, Small for Gestational Age · Infant, Very Low Birth Weight
Primary: Survival Without Moderate/Severe Physiologic Bronchopulmonary Dysplasia (BPD) — 332; 349; 66; 53 Participants
Hepatorenal Syndrome
Primary: Percentage of Participants With Verified HRS Reversal — 29.1; 15.8 percentage of participants
Post-operative Pain · Post-partum Pain · Cesarean Section Complications
Primary: The Total Morphine Milligram Equivalents (MME) Used in the First 72 Postoperative Hours — 60.0; 30 MME
Opioid Addiction
Primary: Changes in Resting State Disorganization Between Baseline and One Week by Person by Lapsed Category — 0.315; 0.328; 0.384; 0.394 Mean default mode network (DMN) z-scores